Results 1 to 10 of about 699,687 (310)

Dynamic soluble changes in sVEGFR1, HGF, and VEGF promote chemotherapy and bevacizumab resistance: A prospective translational study in the BECOX (GEMCAD 09-01) trial [PDF]

Tumor Biology, 2017
Despite initial responsiveness, acquired resistance to both bevacizumab and chemotherapy in metastatic colorectal cancer is universal. We have recently published that in vitro, chronically oxaliplatin resistance upregulates soluble vascular endothelial ...
Estela Pineda, A Salud, E Vila-Navarro, MJ Safont, Beatriz Llorente, J Aparicio, R Vera, P Escudero, E Casado, C Bosch, U Bohn, R Pérez-Carrión, A Carmona, JR Ayuso, T Ripollés, R Bouzas, M Gironella, X García-Albéniz, J Feliu, J Maurel   +19 more
doaj   +3 more sources

Effects of diabetes on myocardial capillary density and serum angiogenesis biomarkers in male rats

Clinics, 2011
INTRODUCTION: Cardiovascular disease is one of the main causes of mortality and morbidity in diabetic patients. This study evaluated the effects of diabetes on myocardial capillary density and several serum angiogenic factors including nitric oxide ...
Majid Khazaei, Ali Reza Fallahzadeh, Mohammad Reza Sharifi, Noushin Afsharmoghaddam, Shaghayegh Haghjooy Javanmard, Ensieh Salehi   +5 more
doaj   +1 more source

Switch to aflibercept or ranibizumab after initial treatment with bevacizumab in eyes with neovascular AMD

BMC Ophthalmology, 2017
Background To evaluate changes in central macular thickness (CMT) and visual outcome in patients with neovascular age-related macular degeneration (AMD) treated initially with bevacizumab and subsequently switched to either aflibercept or ranibizumab ...
Maria Waizel, Margarita G. Todorova, Michael Masyk, Katharina Wolf, Annekatrin Rickmann, Khaled Helaiwa, Björn R. Blanke, Peter Szurman   +7 more
doaj   +1 more source

Clinical-functional and molecular characteristics of comorbid pathology (vibration disease combined with arterial hypertension)

Атеросклероз, 2022
Purpose of the study. Based on the assessment of endothelial and hemostasiological parameters, to study the possibilities of early diagnosis of vascular disorders in case of vibration disease in combination with arterial hypertension.
Oksana N. Gerasimenko, Lyubov A. Shpagina, Alena M. Gorbunova, Ilya S. Shpagin, Yanina S. Sergeeva   +4 more
doaj   +1 more source

Vascular Endothelial Growth Factor Induces Shc Association With Vascular Endothelial Cadherin [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2002
Vascular endothelial (VE)-cadherin is endothelium specific, mediates homophilic adhesion, and is clustered at intercellular junctions. VE-cadherin is required for normal development of the vasculature in the embryo and for angiogenesis in the adult.
Adriana, Zanetti, Maria Grazia, Lampugnani, Giovanna, Balconi, Ferruccio, Breviario, Monica, Corada, Luisa, Lanfrancone, Elisabetta, Dejana   +6 more
openaire   +2 more sources

Intravitreal Injections with Vascular Endothelial Growth Factor Inhibitors: A Practical Approach [PDF]

Ophthalmology and Therapy, 2020
Intravitreal injections with vascular endothelial growth factor inhibitors constitute the most prevalent ophthalmic procedure in developed countries. Historically, there has been steady growth in the number of treatments performed of this kind, and projection studies estimate further growth in such treatments in the future.
Petri, Anne-Sofie, Boysen, Kirstine, Cehofski, Lasse J, van Dijk, Elon H C, Dysli, Chantal, Fuchs, Josefine, Mastropasqua, Rodolfo, Subhi, Yousif   +7 more
openaire   +8 more sources

Vitreous concentrations of vascular endothelial growth factor as a potential biomarker for postoperative complications following pars plana vitrectomy

Archives of Medical Science, 2019
Introduction The aim of the study was to investigate the effects of vascular endothelial growth factor (VEGF) concentration in vitreous on postoperative complications after pars plana vitrectomy (PPV).
Faruk Nisic, Nina Jovanovic, Milka Mavija, Emina Alimanovic-Halilovic, Aida Nisic, Orhan Lepara, Adem Cemerlic   +6 more
doaj   +1 more source

Vascular Endothelial Growth Factor A Inhibition in Gastric Cancer [PDF]

Gastric Cancer, 2014
Angiogenesis is a vital process in the progression and metastasis of solids tumors including gastric adenocarcinoma. Tumors induce angiogenesis by secreting proangiogenic molecules such as vascular endothelial growth factor A (VEGF-A), and VEGF-A inhibition has become a common therapeutic strategy for many cancers.
Do Joong, Park, Nicholas J, Thomas, Changhwan, Yoon, Sam S, Yoon   +3 more
openaire   +2 more sources

In situ formation of poly(vinyl alcohol)–heparin hydrogels for mild encapsulation and prolonged release of basic fibroblast growth factor and vascular endothelial growth factor

Journal of Tissue Engineering, 2016
Heparin-based hydrogels are attractive for controlled growth factor delivery, due to the native ability of heparin to bind and stabilize growth factors.
Justine J Roberts, Brooke L Farrugia, Rylie A Green, Jelena Rnjak-Kovacina, Penny J Martens   +4 more
doaj   +1 more source

Gene Transfers of Vascular Endothelial Growth Factor-A, Vascular Endothelial Growth Factor-B, Vascular Endothelial Growth Factor-C, and Vascular Endothelial Growth Factor-D Have No Effects on Atherosclerosis in Hypercholesterolemic Low-Density Lipoprotein-Receptor/Apolipoprotein B48-Deficient Mice [PDF]

Circulation, 2005
Background— The role of vascular endothelial growth factors (VEGFs) in large arteries has been proposed to be either vasculoprotective or proatherogenic. Because VEGF family members are used for human therapy, it is important to know whether they could enhance atherogenesis.
Pia, Leppänen, Suvi, Koota, Ivana, Kholová, Jonna, Koponen, Christina, Fieber, Ulf, Eriksson, Kari, Alitalo, Seppo, Ylä-Herttuala   +7 more
openaire   +2 more sources