Results 21 to 30 of about 513,814 (378)
Smooth muscle cells and vascular diseases [PDF]
Cardiovascular Research, 2012 Vascular smooth muscle cells (VSMCs) are the stromal cells of the vascular wall, and, due to their myosin/actin interactions, they are also responsible for arterial contractile tonus and regulating blood pressure and flow in relation to specific metabolic demands.
Jean-Baptiste Michel +2 more
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Cells, 2021 Among reactive oxygen species, superoxide mediates the critical vascular redox signaling, resulting in the regulation of the human cardiovascular system.
Kazumi Takaishi +3 more
doaj +1 more source
Smooth Muscle Cells for Vascular Engineering [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2011 In the first decade of this century, ever-increasing scientific and technological advances are revolutionizing our approaches to developing therapies that bring about the promise of personalized medicine and the possibility of regenerative interventions.
Y. Eugene Chen +2 more
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Vascular smooth muscle cell dysfunction in neurodegeneration
Frontiers in Neuroscience, 2022 Vascular smooth muscle cells (VSMCs) are the key moderators of cerebrovascular dynamics in response to the brain’s oxygen and nutrient demands. Crucially, VSMCs may provide a sensitive biomarker for neurodegenerative pathologies where vasculature is compromised.
Genevieve Hayes +7 more
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Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.
Circulation Research, 1994 The signaling pathways involved in the long-term metabolic effects of angiotensin II (Ang II) in vascular smooth muscle cells are incompletely understood but include the generation of molecules likely to affect oxidase activity.
K. Griendling +3 more
semanticscholar +1 more source
Regulation of vascular smooth muscle cell differentiation [PDF]
Journal of Vascular Surgery, 2007 Vascular smooth muscle cell (VSMC) differentiation is an essential component of vascular development. These cells perform biosynthetic, proliferative, and contractile roles in the vessel wall. VSMCs are not terminally differentiated and are able to modulate their phenotype in response to changing local environmental cues.
Kathleen A. Martin +2 more
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Proliferation and apoptosis of smooth muscle and endothelial cells with immune inflammation in cerebrovascular diseases on atherosclerosis background [PDF]
Romanian Journal of Neurology, 2022 The aim – to determine the role of vascular wall cells proliferation and apoptosis with the participation of immune inflammation, and their impact on the development of cerebrovascular disease (CVD) development on the atherosclerosis (AS) background ...
D.S. Mankovskiy +2 more
doaj +1 more source
BMC Cell Biology, 2010 Background Extracellular matrix receptors of the integrin family are known to regulate cell adhesion, shape and functions. The α8 integrin chain is expressed in glomerular mesangial cells and in vascular smooth muscle cells.
Hilgers Karl F +9 more
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iPLA2β overexpression in smooth muscle exacerbates angiotensin II-induced hypertension and vascular remodeling. [PDF]
PLoS ONE, 2012 Calcium independent group VIA phospholipase A(2) (iPLA(2)β) is up-regulated in vascular smooth muscle cells in some diseases, but whether the up-regulated iPLA(2)β affects vascular morphology and blood pressure is unknown.
Lindsay E Calderon +6 more
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The regulation of vascular smooth muscle cell apoptosis [PDF]
Cardiovascular Research, 2000 Apoptosis describes the morphological changes that identify a specific form of regulated cell death. Over recent years, the importance of either aberrant onset or suppression of apoptosis within tissues has become apparent and is associated with the development of several terminal diseases. Here we describe the relevance of apoptosis to the maintenance
Nicola McCarthy, Martin R. Bennett
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