Results 31 to 40 of about 397,979 (354)
The regulation of vascular smooth muscle cell apoptosis [PDF]
Cardiovascular Research, 2000 Apoptosis describes the morphological changes that identify a specific form of regulated cell death. Over recent years, the importance of either aberrant onset or suppression of apoptosis within tissues has become apparent and is associated with the development of several terminal diseases. Here we describe the relevance of apoptosis to the maintenance
Nicola McCarthy, Martin R. Bennett
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Journal of Extracellular Vesicles, 2020 The vascular endothelium and smooth muscle form adjacent cellular layers that comprise part of the vascular wall. Each cell type can regulate the other’s structure and function through a variety of paracrine effectors.
Michael J. Boyer +7 more
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Journal of Clinical Investigation, 1989 Endothelium-derived relaxing factor has been recently identified as nitric oxide. The purpose of this study was to determine if vasodilator drugs that generate nitric oxide inhibit vascular smooth muscle mitogenesis and proliferation in culture.
U. Garg, A. Hassid
semanticscholar +1 more source
Role of smooth muscle progenitor cells in vascular mechanical injury and repair
Medicine in Novel Technology and Devices, 2022 Smooth muscle progenitor cells are precursor cells that express both smooth muscle cell and stem cell markers, and can differentiate into smooth muscle cells under specific condition.
Zhu-feng Dong +7 more
doaj
Caveolin-3 promotes a vascular smooth muscle contractile phenotype
Frontiers in Cardiovascular Medicine, 2015 Epidemiological studies have demonstrated the importance of cardiovascular diseases in Western countries. Among the cell types associated with a dysfunctional vasculature, smooth muscle cells are believed to play an essential role in the development of ...
Jorge L. Gutierrez-Pajares +8 more
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Notch2 and Notch3 function together to regulate vascular smooth muscle development. [PDF]
PLoS ONE, 2012 Notch signaling has been implicated in the regulation of smooth muscle differentiation, but the precise role of Notch receptors is ill defined. Although Notch3 receptor expression is high in smooth muscle, Notch3 mutant mice are viable and display only ...
Qingqing Wang +3 more
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α-Smooth Muscle Actin and ACTA2 Gene Expressions in Vasculopathies
Brazilian Journal of Cardiovascular Surgery, 2015 α-smooth muscle actin, encoded by ACTA2 gene, is an isoform of the vascular smooth muscle actins, typically expressed in the vascular smooth muscle cells contributing to vascular motility and contraction. ACTA2 gene mutations cause a diversity of diffuse
Shi-Min Yuan
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AIMS Bioengineering, 2014 Numerous studies have shown that the proliferation and apoptosis of vascular smooth muscle cells play a key role in restenosis. Artesunate is a triterpenoid with a peroxide structure and its antimalarial, antitumor, and antiangiogenetic activities can ...
Jingwen Zhang +7 more
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Vascular Smooth Muscle Cells and Arterial Stiffening: Relevance in Development, Aging, and Disease.
Physiological Reviews, 2017 The cushioning function of large arteries encompasses distension during systole and recoil during diastole which transforms pulsatile flow into a steady flow in the microcirculation.
P. Lacolley +3 more
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Smooth Muscle-Targeted Overexpression of Peroxisome Proliferator Activated Receptor-γ Disrupts Vascular Wall Structure and Function. [PDF]
PLoS ONE, 2015 Activation of the nuclear hormone receptor, PPARγ, with pharmacological agonists promotes a contractile vascular smooth muscle cell phenotype and reduces oxidative stress and cell proliferation, particularly under pathological conditions including ...
Jennifer M Kleinhenz +10 more
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