Results 111 to 120 of about 15,633 (213)
VDAC and Mitochondrial Bioenergetics in Cancer Biology and Therapeutics [PDF]
, 2022 The contribution of mitochondria to cancer cell metabolism is a continuously growing research field. Enhanced glycolysis and partial suppression of mitochondrial metabolism, reciprocally dependent in many tumors, characterize the pro-survival and ...
Heslop, Kareem Akeam
core
The VDAC channel: Molecular basis for selectivity
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2016 The voltage dependent anion-selective channel, VDAC, is the major permeability pathway by which molecules and ion cross the mitochondrial outer membrane. This pathway has evolved to optimize the flow of these substances and to control this flow by a gating process that is influenced by a variety of factors including transmembrane voltage.
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To Include Plasmalemmal VDAC/Porin Pays
Journal of Biological Chemistry, 2012 The paper of Teijido et al. (1) will hopefully stimulate closer contacts between structure people and physiologists in the voltage-dependent anion channel (VDAC) community. It refines the VDAC model of Marco Colombini and also refers to the accessibility of the VDAC N-terminal end at mitochondria or the outer surface of the plasmalemma.
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VDAC Regulation by Cytosolic Proteins [PDF]
Biophysical Journal, 2009 Voltage-dependent anion channel VDAC, positioned on the interface between mitochondria and the cytosol, is at the control point of mitochondria life and death. This large channel plays the role of a “switch” that defines in which direction mitochondria will go: to normal respiration or to suppression of mitochondria metabolism that leads to apoptosis ...
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Specific VDAC inhibitors: phosphorothioate oligonucleotides
, 2020 VDAC channels are ancient, highly-conserved voltage-gated channels in the mitochondrial outer membrane. They are the pathways by which metabolites travel between the cytosol and mitochondria.
Marco Colombini, C A Stein
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Voltage-dependent anion-selective channel (VDAC) in the plasma membrane [PDF]
, 2010 Voltage-dependent anion channels (VDACs) have originally been characterized as mitochondrial porins. Starting in the late 1980s, however, evidence began to accumulate that VDACs can also be expressed in plasma membranes.
Lane, Darius J.R. +3 more
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A preregistration for a study on value-driven attentional capture (VDAC) in a sustained attention ...
Shivang Shelat
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BNIP3 induces MPT by interacting with VDAC.
, 2014 A, BNIP3-induced MPT. Calcein release was presented as the percentage of calcein escaped from mitochondria during the 30-minute incubation ...
Jiming Kong (143823) +2 more
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Ceramides disrupt hexokinase HKI-VDAC complex assembly and modulate VDAC tilting
Abstract Ceramides bind voltage-dependent anion channels (VDACs) to promote mitochondrial apoptosis. However, the underlying mechanism is unclear. Ceramide binding relies on a charged, bilayer-facing glutamate that also controls complex formation between VDACs and pro-survival hexokinase HKI, suggesting that ceramides may exert their ...
Michael Timme +2 more
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VDAC: the wizard of mitochondrial OM
, 2014 Voltage dependent anion channels (VDAC) are the most abundant proteins in the outer mitochondrial membrane. Although they are essential in metabolite exchange, cell defense and apoptosis, the molecular mechanism of these VDAC-mediated processes remains ...
Psakis, Georgios +3 more
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