Objective Systemic sclerosis (SSc) is a rare but severe autoimmune disease characterized by immune dysregulation, fibrosis, and vasculopathy. Although previous studies have highlighted the presence of functional autoantibodies targeting the angiotensin II receptor type 1 (AT1) and endothelin‐1 type A receptor (ETAR), leading to autoantibody‐mediated ...
Wieke M. van Oostveen+8 more
wiley +1 more source
Advances in Targeted and Chemotherapeutic Strategies for Colorectal Cancer: Current Insights and Future Directions. [PDF]
Shaham SH, Vij P, Tripathi MK.
europepmc +1 more source
Objective Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments. Methods Plasma proteomic profiling of 184 proteins was performed in two cohorts. Cohort 1 included
Robert T. Maughan+15 more
wiley +1 more source
A Darwinian approach to the development of the vascular system in the vertebrates. [PDF]
Ribatti D.
europepmc +1 more source
Peripheral Biomarker Signatures in Rheumatoid Arthritis–Associated Interstitial Lung Disease
Objective Rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) is a significant cause of morbidity and mortality among patients with RA, yet effective risk stratification for RA‐ILD is lacking. We sought to characterize unique peripheral blood biomarker signatures in RA that could improve RA‐ILD discrimination beyond clinical and genetic ...
Austin M. Wheeler+18 more
wiley +1 more source
Understanding Neovascularization in Glioblastoma: Insights from the Current Literature. [PDF]
Ballato M+16 more
europepmc +1 more source
Altered Expression Levels of Angiogenic Peptides in the Carotid Body of Spontaneously Hypertensive Rats. [PDF]
Atanasova DY+6 more
europepmc +1 more source
Sacrificial strategy towards the formation of vascular‐like networks in volumetric tissue constructs
This mini‐review highlights the latest progress in the sacrificial template‐enabled creation of patent vascular‐like networks, which can be incorporated into volumetric tissue constructs. Such microchannel networks can provide an immediate supply of nutrition and O2 to those cells residing next to the channels.
Christian Buckley+5 more
wiley +1 more source
Case report: Bevacizumab-induced cerebrovascular events: a case series report and literature review. [PDF]
Chen K, Jiang B, Yan H, Yang L, Chen Z.
europepmc +1 more source
The contribution of extracellular RNA and its derived biomaterials in disease management
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei+8 more
wiley +1 more source