Results 71 to 80 of about 29,745,998 (266)
Brazilian Journal of Medical and Biological Research, 2018 Neonatal asphyxia occurs due to reduction in oxygen supply to vital organs in the newborn. Rapid restoration of oxygen to the lungs after a long period of asphyxia can cause lung injury and decline of respiratory function, which result from the activity ...
R.L. Figueira +6 more
doaj +1 more source
The Molecular Basis of VEGFR-1 Signal Transduction Pathways in Primary Human Monocytes [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2008 Objective— Arteriogenesis, the growth of preexisting arterioles into functional arteries, is dependent on the proper function of monocytes. Likewise, wound healing is monocyte-dependent. The activation of vascular endothelial growth factor receptor-1 (VEGFR-1) in monocytes induces a chemotactic ...
Vadim, Tchaikovski +2 more
openaire +2 more sources
Activation of VEGFR-1 and VEGFR-2 by UVA involves activation of PKC and SFK.
, 2013 (a) Western blotting detection of P-VEGFR-1 and P-VEGFR-2 in keratinocytes 12 h after treatment of 10 J/cm2 UVA with or without pre-incubation of Go6976 (0.5 µM), or rottlerin (5.0 µM) for 1 h. (b) The densitometric analysis of P-VEGFR-1 and P-VEGFR-2 in
Zhong-Fa Lu (285979) +5 more
core +1 more source
VEGFR–1 and VEGFR–2 expression in native ECs of HD1 and HD2.
, 2022 Median and standard error was evaluated at day 1, 5, 15, 25 and 50 of cultivation. By using Mann–Whitney U test for unpaired data, it was shown that VEGFR–2 was higher expressed than VEGFR–1 at every point of investigation in both cultures (p (DOCX)
Christina Herre (12475755) +4 more
core +1 more source
Clinical and Genetic Factors Associated With Regression in Children With Autism Spectrum Disorders
Autism Research, EarlyView.ABSTRACT Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition with complex genetic and environmental underpinnings. A clinically significant subset of children with ASD experience developmental regression (regASD), characterized by the acute loss of previously acquired skills. The mechanisms, predictors, and molecular basis of
Anna Maruani +7 more
wiley +1 more source
Indonesian Journal of Obstetrics and Gynecology, 2012 Objectives: To understand the expression of placental vascular endothelial growth factor receptor (VEGFR-1) in severe preeclampsia with complication (eclampsia and HELLP syndrome). Methods: The study was an observational study with cross sectional design,
Efendi Lukas
doaj +1 more source
Down-regulation of Gab1 inhibits cell proliferation and migration in hilar cholangiocarcinoma. [PDF]
PLoS ONE, 2013 Hilar cholangiocarcinoma is a highly aggressive malignancy originating from the hilar biliary duct epithelium. Due to few effective comprehensive treatments, the prognosis of hilar cholangiocarcinoma is poor. In this study, immunohistochemistry was first
Haiquan Sang +3 more
doaj +1 more source
UVA promoted tyrosine phosphorylation of VEGFR-1 and VEGFR-2 in normal human keratinocytes.
, 2013 (a) The time-dependent phosphorylation of VEGFR-1 and VEGFR-2 in keratinocytes induced by 10 J/cm2 UVA. Cells were harvested 0, 2, 4, 8, 12, 24 h after irradiation. (b) The densitometric analysis of (a).
Zhong-Fa Lu (285979) +5 more
core +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation [PDF]
Cardiovascular Research, 2016 In developing blood vessel networks, the overall level of vessel branching often correlates with angiogenic sprout initiations, but in some pathological situations, increased sprout initiations paradoxically lead to reduced vessel branching and impaired vascular function. We examine the hypothesis that defects in the discrete stages of angiogenesis can
John C, Chappell +10 more
openaire +2 more sources