Results 51 to 60 of about 21,287,561 (278)

Differential expression of Vegfr-2 and its soluble form in preeclampsia.

PLoS ONE, 2012
BackgroundSeveral studies have suggested that the main features of preeclampsia (PE) are consequences of endothelial dysfunction related to excess circulating anti-angiogenic factors, most notably, soluble sVEGFR-1 (also known as sFlt-1) and soluble ...
Carine Munaut, Sophie Lorquet, Christel Pequeux, Capucine Coulon, Jeanne Le Goarant, Frédéric Chantraine, Agnès Noël, Frédéric Goffin, Vassilis Tsatsaris, Damien Subtil, Jean-Michel Foidart   +10 more
doaj   +1 more source

The role of the FLT1 gene alternative splicing in the fetal growth retardation development

Acta Biomedica Scientifica
Background. Fetal growth restriction (FGR) is a major pregnancy complication often associated with placental dysfunction and angiogenic imbalance. The FLT1 gene encodes VEGFR-1, producing both membrane receptors and soluble isoforms (sFlt-1) through ...
M. M. Gavrilenko, E. A. Trifonova, A. A. Babovskaya, M. G. Swarovskaya, E. V. Izhoykina, V. A. Stepanov   +5 more
doaj   +1 more source

Mediating EGFR-TKI Resistance by VEGF/VEGFR Autocrine Pathway in Non-Small Cell Lung Cancer

Cells, 2022
NSCLC treatment includes targeting of EGFR with tyrosine kinase inhibitors (TKIs) such as Erlotinib; however, resistance to TKIs is commonly acquired through T790M EGFR mutations or overexpression of vascular endothelial growth factor receptor-2 (VEGFR-2)
Chike Osude, Leo Lin, Meet Patel, Adam Eckburg, Joseph Berei, Adijan Kuckovic, Namrata Dube, Aayush Rastogi, Shruti Gautam, Thomas J. Smith, Shylendra B. Sreenivassappa, Neelu Puri   +11 more
doaj   +1 more source

Serum Levels of VEGF-A and Its Receptors in Patients in Different Phases of Hemorrhagic and Ischemic Strokes

Current Issues in Molecular Biology, 2022
Vascular endothelial growth factors (VEGFs) are important regulators of angiogenesis, neuroprotection, and neurogenesis. Studies have indicated the association of VEGF dysregulation with the development of neurodegenerative and cerebrovascular diseases ...
Anastasiya S. Babkina, Mikhail Ya. Yadgarov, Irina V. Ostrova, Vladislav E. Zakharchenko, Artem N. Kuzovlev, Andrey V. Grechko, Maxim A. Lyubomudrov, Arkady M. Golubev   +7 more
doaj   +1 more source

Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation [PDF]

Cardiovascular Research, 2016
In developing blood vessel networks, the overall level of vessel branching often correlates with angiogenic sprout initiations, but in some pathological situations, increased sprout initiations paradoxically lead to reduced vessel branching and impaired vascular function. We examine the hypothesis that defects in the discrete stages of angiogenesis can
John C, Chappell, Julia G, Cluceru, Jessica E, Nesmith, Kevin P, Mouillesseaux, Vanessa B, Bradley, Caitlin M, Hartland, Yasmin L, Hashambhoy-Ramsay, Joseph, Walpole, Shayn M, Peirce, Feilim, Mac Gabhann, Victoria L, Bautch   +10 more
openaire   +2 more sources

VEGFR-2 Expression in Glioblastoma Multiforme Depends on Inflammatory Tumor Microenvironment

International Journal of Inflammation, 2015
Glioblastoma multiforme (GBM) is one of the most angiogenic tumors. However, antiangiogenic therapy has not shown significant clinical efficacy. The aim of our study was to evaluate the impact of inflammatory tumor microenvironment on the expression of ...
Jana Jaal, Marju Kase, Ave Minajeva, Mikk Saretok, Aidi Adamson, Jelizaveta Junninen, Tõnis Metsaots, Tõnu Jõgi, Madis Joonsalu, Markus Vardja, Toomas Asser   +10 more
doaj   +1 more source

VEGF and VEGFR‐1 are coexpressed by epithelial and stromal cells of renal cell carcinoma [PDF]

Cancer, 2007
AbstractBACKGROUND.Tumor angiogenesis is a dynamic process that plays a major role in cancer progression. Vascular endothelial growth factor (VEGF) and its receptors play a pivotal role in angiogenesis. The expression of VEGF and its receptors VEGFR‐1 and VEGFR‐2 in renal cell carcinoma (RCC) was investigated in the perspective of anti‐VEGF treatments ...
Jacqueline, Rivet, Samia, Mourah, Hideyuki, Murata, Nicolas, Mounier, Helena, Pisonero, Pierre, Mongiat-Artus, Pierre, Teillac, Fabien, Calvo, Anne, Janin, Christine, Dosquet   +9 more
openaire   +2 more sources

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Expression and Significances of Contactin-1 in Human Gastric Cancer

Gastroenterology Research and Practice, 2013
Background. This study aimed at determining the relationship between vascular endothelial growth factor-C (VEGF-C), vascular endothelial growth factor receptor-3 (VEGFR-3), and contactin-1 (CNTN-1) expression in gastric cancer (GC ...
Ji-Wei Yu, Sheng-Hua Wu, Rui-qi Lu, Ju-gang Wu, Xiao-Chun Ni, Gou-cai Zhou, Hai-guang Jiang, Lin-Hai Zheng, Xiao-Qiang Li, Guang-Ye Du, Bo-Jian Jiang   +10 more
doaj   +1 more source

Lv-vegfr-10-Ig expression during BC transfating.

, 2019
(A) Control gastrula. Lv-vegfr-10-Ig is expressed at high levels by PMCs (arrow), as previously reported [9]. (B) PMC(−) embryo, 2 hpd. Expression of Lv-vegfr-10-Ig is evident in the invaginating vegetal plate (arrow), a region that includes presumptive ...
Ashrifia Adomako-Ankomah (7401002), Charles A. Ettensohn (5062514)   +1 more
core   +1 more source