Results 61 to 70 of about 8,038 (173)
An update on the landscape of collagen bioactive fragments
The FEBS Journal, EarlyView.The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley +1 more source
Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy. [PDF]
PLoS ONE, 2011 Overexpression of EGFR and versican has been reported in association with breast cancers. Considered oncogenic, these molecules may be attractive therapeutic targets.
William Weidong Du +9 more
doaj +1 more source
Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health
The FEBS Journal, EarlyView.Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin +2 more
wiley +1 more source
Redox Report, 2022 Objective Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of genistein in modulating versican/platelet derived growth factor (PDGF ...
Yousra M. El-Far +4 more
doaj +1 more source
Periodontology 2000, EarlyView.Abstract This systematic review aimed to evaluate all available evidence across all fields of medicine regarding the comparative effectiveness of platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF). A comprehensive search was conducted in PubMed, Scopus, and Web of Science up to September 30, 2024.
Nima Farshidfar +6 more
wiley +1 more source
Axon Initial Segment: Structure, Biological Functions, Diseases, and Therapeutic Targets
MedComm, Volume 7, Issue 4, April 2026.The axon initial segment (AIS) is a specialized axonal domain critical for maintaining neuronal polarity, action potential initiation, and network stability. This review summarizes the necessary elements for maintaining AIS structure and plasticity, discussing crucial biological functions of AIS in neuronal signaling and the neural circuit homeostasis,
Dong‐Yan Song +4 more
wiley +1 more source
Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim +11 more
wiley +1 more source
BMC Cancer, 2012 Background Versican is detected in the interstitial tissues at the invasive margins of breast carcinoma, is predictive of relapse, and negatively impacts overall survival rates.
Du William +7 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 3, March 2026.This integrated clinical approach optimizes the reproductive cycle in several steps, starting with nutrition (A): restricting carbohydrates and inducing ketosis to reduce inflammation and improve insulin sensitivity, which benefits follicular development.
Tania G. Rojas‐Pérez +7 more
wiley +1 more source
Respiratory Research, 2018 Background Prenatal glucocorticoid treatment decreases alveolar tissue volumes and facilitates fetal lung maturation, however the mechanisms responsible are largely unknown. This study examines whether changes in versican levels or sulphation patterns of
Annie R. A. McDougall +6 more
doaj +1 more source