Results 81 to 90 of about 8,038 (173)

ADAMTS5 Orchestrates Cell Lineage Specific Patterning and Extracellular Matrix Organization During Semilunar Valve Development

Journal of Cardiovascular Development and Disease
Aortic valve (AV) disease affects about 5% of the aging population, with AV replacement as the only treatment option. Histopathology indicates that accumulation of extracellular matrix (ECM) proteoglycans correlates with dysfunctional AVs.
Loren E. Dupuis, Joshua J. Mifflin, Amy L. Marston, Jeremy P. Laxner, Christine B. Kern   +4 more
doaj   +1 more source

Overexpression of TGF-β Inducible microRNA-143 in Zebrafish Leads to Impairment of the Glomerular Filtration Barrier by Targeting Proteoglycans

Cellular Physiology and Biochemistry, 2016
Background: TGF-β is known as an important stress factor of podocytes in glomerular diseases. Apart from activation of direct pro-apoptotic pathways we wanted to analyze micro-RNA (miRs) driven regulation of components involved in the integrity of the ...
Janina Müller-Deile, Finn Gellrich, Heiko Schenk, Patricia Schroder, Jenny Nyström, Johan Lorenzen, Hermann Haller, Mario Schiffer   +7 more
doaj   +1 more source

Versican、CTGF、TGFβ1在子宫内膜样腺癌及子宫内膜上皮内瘤变中的表达和意义

Zhongguo shiyan zhenduanxue, 2016
目的探讨多功能蛋白聚糖（Versican）、结缔组织生长因子（CTGF）、转化生长因子β1（TGFβ1）在子宫内膜样腺癌（EA）及子宫内膜上皮内瘤变（EIN）中的表达及三者相关性。方法采用免疫组织化学方法对76例EA和35例EIN中Versican、CTGF、TGFβ1的表达情况进行了分析,阐述其在EA及EIN中的表达特征及相互关系。结果在76例EA中Versican、CTGF、TGFβ1阳性表达率分别为75%,65.8%,69.7%,在35例EIN中阳性表达率分别为42.9%,37.1%,37.1 ...
汪锋, 宋晓燕, 胡玉崇, 贺慧杰, 武慧, 张帆, 钗丽干   +6 more
doaj  

Versican V0/V1 Is Essential For The Proliferation Of Mdpcs

International Dental Journal
Aim or purpose: To evaluate the effect of Versican V0/V1 isoforms on the proliferation of mouse dental papilla cells (mDPCs). Materials and methods: Immunofluorescence staining was performed to observe the expression of GAG-β, GAG-α and EdU.
Jiayan Wu, Beizhan Jiang
doaj   +1 more source

Versican modulates cellular responses [PDF]

Respiratory Research, 2001
Ammit Alaina J, Hirose J, Kawashima H, Yoshie O, Tashiro K, Miyasaka M   +5 more
openaire   +2 more sources

Influencia de componentes de la matriz extracelular en la agresividad y potencial invasor del cáncer cérvicouterino: ¿Qué hay de nuevo?

Revista Chilena de Obstetricia y Ginecología, 2011
El cáncer cérvico uterino (CCU) es una patología de alta incidencia y mortalidad. La investigación hasta ahora se ha enfocado en estudiar su asociación con virus papiloma.
Paula Segura H, Leonor Moyano S
doaj  

Versican Core Protein [PDF]

, 2020
openaire   +1 more source

Genetic variants in the exon region of versican predict survival of patients with resected early-stage hepatitis B virus-associated hepatocellular carcinoma

Cancer Management and Research, 2018
Xiaoguang Liu,* Chuangye Han,* Xiwen Liao, Long Yu, Guangzhi Zhu, Hao Su, Wei Qin, Sicong Lu, Xinping Ye, Tao Peng Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region,
Liu X, Han C, Liao X, Yu L, Zhu G, Su H, Qin W, Lu S, Ye X, Peng T   +9 more
doaj  

Proteoglycans as Biomarkers of Medial Degeneration in Acute Stanford Type A Aortic Dissection. [PDF]

Rev Cardiovasc Med
Bagaber G, Song W, Fu G, Hu K, Wang Z, Hu Y, Wei L, Chen J.   +7 more
europepmc   +1 more source

The ADAMTS family: from extracellular matrix proteases to orchestrators of fibrosis. [PDF]

Cell Commun Signal
Yuan Y, Guo P, Song Y, Yu Z, Song B.
europepmc   +1 more source