Results 71 to 80 of about 6,573 (255)

A simple method to isolate fatty acids and fatty alcohols from wax esters in a wax-ester rich marine oil.

PLoS ONE, 2023
Calanus finmarchicus is one of the most important zooplankton species in the North Atlantic. The zooplankton is currently being harvested and industrially processed to a marine oil product for human consumption as a marine nutraceutical containing long ...
Pauke Carlijn Schots, Guro Kristine Edvinsen, Ragnar Ludvig Olsen   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Can early intake of dietary omega-3 predict childhood externalizing behaviour? [PDF]

, 2009
Aim: To determine whether maternal and child intake of dietary omega-3 (n-3) fatty acids (FA), together with the presence or absence of breast-feeding, predicted psychiatric diagnosis of externalizing disorders in childhood.
Samara, Muthanna, Waylen , Andrea E., Goodman, R, Waylen, Andrea E., Samara, M., Waylen, A., Samara, M, Ford, T., Ford, Tamsin, Wolke, D., Wolke, Dieter, Goodman, Robert, Waylen, A, Wolke, D, Goodman, Robert, MRCPsych, Ford, T, Goodman, R.   +16 more
core   +1 more source

Circulating Very Long‐Chain Saturated Fatty Acids and Heart Failure: The Cardiovascular Health Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Circulating very‐long‐chain saturated fatty acids (VLSFAs) are integrated biomarkers of diet and metabolism that may point to new risk pathways and potential targets for heart failure (HF) prevention.
Rozenn N. Lemaitre, Barbara McKnight, Nona Sotoodehnia, Amanda M. Fretts, Waqas T. Qureshi, Xiaoling Song, Irena B. King, Colleen M. Sitlani, David S. Siscovick, Bruce M. Psaty, Dariush Mozaffarian   +10 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Very-long-chain fatty acids are required for cell plate formation during cytokinesis in Arabidopsis thaliana

, 2011
Acyl chain length is thought to be crucial for biophysical properties of the membrane, in particular during cell division, when active vesicular fusion is necessary.
Lionel Gissot, Tellier, F., Jessica Marion, Napier, Johnathan A., Jean-Denis Faure, Johnathan A. Napier, Moreau, P., Liên Bach, Gissot, Lionel, Faure, J-D., Béatrice Satiat-Jeunemaître, Patrick Moreau, Satiat-Jeunemaitre, B., Jean-Christophe Palauqui, Bach, L., Palauqui, Jean-Christophe, Marion, Jessica, Tellier, Frédérique, Marion, J., Frédérique Tellier, Satiat-Jeunemaître, Béatrice, Bach, Liên, Moreau, Patrick, Faure, Jean-Denis, Napier, J. A., Gissot, L., Palauqui, J-C.   +26 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Effects of induced subacute ruminal acidosis on milk fat content and milk fatty acid profile [PDF]

, 2008
Two lactating dairy cows fitted with a rumen cannula received successively diets containing 0%, 20%, 34% and again 0% of wheat on a dry matter basis. After 5, 10 and 11 days, ruminal pH was measured between 8:00 and 16:00 hours, and milk was analysed for
Troegeler-Meynadier, Annabelle, Videau, Yannick, Enjalbert, Francis, Nicot, Marie-Claude   +3 more
core   +1 more source

Cholesteryl esters as a depot for very long chain fatty acids in human meibum*

Journal of Lipid Research, 2009
Human meibomian gland secretions (also known as meibum) were analyzed for the presence of cholesteryl esters (Chl-E) using HPLC in combination with atmospheric pressure chemical ionization mass spectrometry.
Igor A. Butovich
doaj   +1 more source