Results 31 to 40 of about 4,557 (114)

The Brain‐Gut Axis in Parkinson's Disease Pathology

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Exposure to environmental toxins induces gut dysbiosis, increases intestinal epithelial barrier permeability, immune activation, and oxidative stress, promoting α‐syn misfolding and propagation. Brainstem DMV neurons exhibit α‐syn pathology, dysregulating neuronal excitability and vagal control of GI functions.
Kudret Selin Ozkaya, Kirsteen N. Browning   +1 more
wiley   +1 more source

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu, Xinyue Zhou, Ruotong Meng, Yanxi Chen, You Chen, Blake Highet, Maurice Curtis, Bernhard Hirt, Shunying Yu, Jin Zhou, Linya You   +10 more
wiley   +1 more source

Impact of HIV-1 tat protein on methamphetamine-induced inhibition of vesicular monoamine transporter2-mediated dopamine transport and methamphetamine conditioned place preference in HIV-1 tat transgenic mice

European Journal of Pharmacology
Perturbation of dopamine transmission has been implicated as a contributing factor in HIV-1 associated neurocognitive disorders with concurrent methamphetamine (METH) abuse. We have demonstrated that the HIV-1 protein, transactivator of transcription (Tat), decreases dopamine transport through inhibition of vesicular monoamine transporter2 (VMAT2 ...
Jun Zhu, Abagail B. Cirincione, Matthew J. Strauss, Sarah E. Davis, Shainnel O. Eans, Danielle K. Tribbitt, Nadine Alshakhshir, Jay P. McLaughlin   +7 more
openaire   +2 more sources

Erratum to: Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Children’s Oncology Group [PDF]

European Journal of Nuclear Medicine and Molecular Imaging, 2016
William Temple, Lori Mendelsohn, Grace E. Kim, Erin Nekritz, W. Clay Gustafson, Lawrence Lin, Kathy Giacomini, Arlene Naranjo, Collin Van Ryn, Marguerite T. Parisi, Barry L. Shulkin, Gregory A. Yanik, Susan G. Kreissman, Michael Hogarty, Katherine K. Matthay, Steven G. DuBois   +15 more
openaire   +1 more source

Dopamine-Derived Oxidative Stress in Attention-Deficit/Hyperactivity Disorder: A Narrative Review of Molecular Mechanisms, Neural Circuitry, and Therapeutic Implications. [PDF]

Antioxidants (Basel)
Țocu G, Ștefănescu BI, Țocu L, Dimofte F, Luțenco V, Stavăr Matei L, Dănilă MD, Marin MC, Matei MN, Mihailov OM, Iacobescu P, Mihailov R.   +11 more
europepmc   +1 more source

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions. [PDF]

Adv Sci (Weinh)
Zhao Y, Zhang H, Yang Y, Chen WD, Wang YD.   +4 more
europepmc   +1 more source

Engineering Nanocarriers for Dopamine Stabilization and Targeted Brain Delivery: Mechanisms, Approaches and Translational Challenges. [PDF]

Int J Nanomedicine
Patra S, Nathani A.
europepmc   +1 more source

Molecular basis of vesicular monoamine transport and neurological drug interactions. [PDF]

Cell Rep
Ye J, Chen H, Ammerman A, Wang Y, Wang K, Xu J, Liu B, Li W.   +7 more
europepmc   +1 more source

Tryptophan's Journey Through Pregnancy: The Role of Serotonin. [PDF]

Int J Tryptophan Res
Gendrot B, Vaillancourt C, Fouquet G.
europepmc   +1 more source

Disruption of Synaptic Vesicle Trafficking in Alzheimer's and Parkinson's Disease: Mechanisms and Therapeutic Implication. [PDF]

Int J Mol Sci
Zhu Y, Zhao L, Li Y, Tian M, Liao Y, Huang J, Guo P, Xie Y.   +7 more
europepmc   +1 more source