Results 21 to 30 of about 480 (154)

Testing the properties of beam-dose monitors for VHEE-FLASH radiation therapy [PDF]

, 2022
Very High Energy Electrons (VHEE) of 50 - 250 MeV are an attractive choice for FLASH radiation therapy (RT). Before VHEE-FLASH RT can be considered for clinical use, a reliable dosimetric and beam monitoring system needs to be developed, able to measure ...
Burrows, Philip, Silari, Marco, Heracleous, N., Salvachua, B., Korysko, Pierre, Burrows, P. N., Dosanjh, M., Korysko, P., Gerbershagen, Alexander, Bateman, Joseph, Farabolini, Wilfrid, Rieker, V. F., Corsini, Roberto, Corsini, R., Silari, M., Heracleous, Natalie, Dosanjh, Manjit, Morales, S., Salvachúa, Belen, Zorloni, G., Farabolini, W., Zorloni, Gabriele, Morales Vigo, Sara, Dyks, L. A., Bateman, J. J., Dyks, Luke, Murtas, Fabrizio, Gerbershagen, A.; id_orcid, Murtas, F., Rieker, Vilde   +29 more
core   +6 more sources

Beam optics study for a potential VHEE beam delivery system [PDF]

Journal of Physics: Conference Series, 2023
VHEE (Very High Energy Electron) therapy can be superior to conventional radiotherapy for the treatment of deep seated tumours, whilst not necessarily requiring the space and cost of proton or heavy ion facilities.
Robertson, C. S., Burrows, P. N., Dosanjh, M., Latina, A., Gerbershagen, A.; id_orcid, P N Burrows, A Gerbershagen, C S Robertson, A Latina, M Dosanjh   +9 more
core   +4 more sources

Status of VHEE Radiotherapy Related Studies at the CLEAR User Facility at CERN [PDF]

, 2021
Despite the increase in interest in using Very High Energy Electron (VHEE) beams for cancer radiotherapy many unanswered questions in its development remain. The use of test facilities will be an essential tool used to solve these issues.
Farabolini, Wilfrid, Corsini, Roberto, Dyks, Luke, Korysko, Pierre, Gilardi, Antonio, Sjobak, Kyrre   +5 more
core   +2 more sources

Evaluating very high energy electron RBE from nanodosimetric pBR322 plasmid DNA damage

Scientific Reports, 2021
This paper presents the first plasmid DNA irradiations carried out with Very High Energy Electrons (VHEE) over 100–200 MeV at the CLEAR user facility at CERN to determine the Relative Biological Effectiveness (RBE) of VHEE.
K. L. Small, N. T. Henthorn, D. Angal-Kalinin, A. L. Chadwick, E. Santina, A. Aitkenhead, K. J. Kirkby, R. J. Smith, M. Surman, J. Jones, W. Farabolini, R. Corsini, D. Gamba, A. Gilardi, M. J. Merchant, R. M. Jones   +15 more
doaj   +3 more sources

VHEE High Dose Rate Dosimetry Studies in CLEAR

, 2022
International audienceThe 200 MeV electron beam of the CERN Linear Accelerator for Research (CLEAR) user facility at CERN has been intensively used to study the potential use of Very High Energy Electrons (VHEE) in cancer radiotherapy.
Bateman, Joseph, Farabolini, Wilfrid, Corsini, Roberto, Dyks, Luke, Korysko, Pierre, Rieker, Vilde   +5 more
core   +2 more sources

SAFEST. A compact C-band linear accelerator for VHEE-FLASH radiotherapy [PDF]

, 2023
FLASH Radiotherapy is a revolutionary new technique in the cancer cure. Several pre-clinical studies have demonstrated that treatment with electron radiation delivered with mean dose rates above 100Gy/s, an ultra-high instantaneous dose rate > 106Gy/s,
L. Palumbo, R. Di Raddo, A. Sarti, G. Milluzzo, A. De Gregorio, B. Spataro, L. Faillace, F. Romano, A. Gallo, L. Ficcadenti, F. Di Martino, G. Silvi, F. Cardelli, L. Giuliano, M. Migliorati, G. Cuttone, G. Torrisi, D. Alesini, G. Franzini, G. Sorbello, L. Piersanti, V. Patera, A. Vannozzi, A. Mostacci, M. Magi, F. Bosco, M. Bisogni, M. Carillo, D. De Arcangelis, G. Mauro, G. Cirrone, D. Francescone, E. Chiadroni, G. Franciosini   +33 more
core   +2 more sources

New insights on clinical perspectives of FLASH radiotherapy: from low- to very high electron energy [PDF]

Frontiers in Oncology, 2023
Radiotherapy (RT) is performed in approximately 75% of patients with cancer, and its efficacy is often hampered by the low tolerance of the surrounding normal tissues.
Stefano Ursino, Stefano Ursino, Stefano Ursino, Giovanni Gadducci, Giovanni Gadducci, Noemi Giannini, Noemi Giannini, Alessandra Gonnelli, Alessandra Gonnelli, Taiushia Fuentes, Taiushia Fuentes, Fabio Di Martino, Fabio Di Martino, Fabiola Paiar, Fabiola Paiar, Fabiola Paiar   +15 more
doaj   +2 more sources

Etude et modélisation de la radiothérapie par électrons de très haute énergie (VHEE)

Le développement de méthodes innovantes susceptibles de réduire la sensibilité des tissus sains aux radiations, tout en maintenant l'efficacité du traitement sur la tumeur, est un aspect central de l'amélioration de l'efficacité de la radiothérapie pour ...
Ronga, Maria Grazia
core   +5 more sources

Characterization of Titanium Effects on Very High Energy Electron (VHEE) Beams [PDF]

E3S Web of Conferences
Very High Energy Electron (VHEE) therapy is gaining attention as an innovative approach for treating deep-seated tumors, combining favorable dose deposition, sharp lateral penumbra, and compatibility with ultra-high dose rate (FLASH) delivery. A critical
Essaidi El Mehdi, Krim Mustapha, Didi Abdessamad, Tantaoui Meriem, Kaanouch Othmane   +4 more
doaj   +2 more sources

Extending deterministic transport capabilities for very-high and ultra-high energy electron beams [PDF]

Scientific Reports
Focused Very-High Energy Electron (VHEE, 50–300 MeV) and Ultra-High Energy Electron (UHEE, > 300 MeV) beams can accurately target both large and deeply seated human tumors with high sparing properties, while avoiding the spatial requirements and cost of ...
Ahmed Naceur, Charles Bienvenue, Paul Romano, Cornelia Chilian, Jean-François Carrier   +4 more
doaj   +2 more sources