Results 101 to 110 of about 54,904 (251)

Rydberg-London Potential for Diatomic Molecules and Unbonded Atom Pairs

, 2004
We propose and test a pair potential that is accurate at all relevant distances and simple enough for use in large-scale computer simulations. A combination of the Rydberg potential from spectroscopy and the London inverse-sixth-power energy, the ...
Axilrod, Aziz, Aziz, Cheng, Dham, Douketis, Ermler, Ferrante, Hulbert, Kevin Cahill, Klein, Krupenie, Lofthus, Morse, Muto, Rees, Rydberg, Steele, Tang, V. Adrian Parsegian, Varnshi, Viegas, Weissman   +22 more
core   +1 more source

Evaluation of ASC as a therapeutic target for Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract Neuroinflammation is increasingly recognized as a central contributor to the pathogenesis and progression of Alzheimer's disease (AD). The apoptosis‐associated speck‐like protein containing a CARD (ASC), encoded by the PYCARD gene, plays a critical role in the formation of multiple inflammasomes, including NLRP3, a key mediator of inflammation
W. Brent Clayton, Joshua A. Kulas, Jiahui Liu, Nidhi Walia, Claudia Rangel‐Barajas, Travis Johnson, Jie Zhang, Kun Huang, Andrew D. Mesecar, Jeffrey L. Dage, Bruce T. Lamb, Alan D. Palkowitz, Timothy I. Richardson   +12 more
wiley   +1 more source

Characterization of plant produced VHH antibodies against cobra venom toxins for antivenom therapy

Biotechnology Reports
Cobra (Naja kaouthia) venom contains many toxins including α-neurotoxin (αNTX) and phospholipase A2 (PLA2), which can cause neurodegeneration, respiratory failure, and even death.
Sarocha Vitayathikornnasak, Kaewta Rattanapisit, Ashwini Malla, Pipob Suwanchaikasem, Richard Strasser, Narach Khorattanakulchai, Kanokporn Pothisamutyothin, Wanatchaporn Arunmanee, Waranyoo Phoolcharoen   +8 more
doaj   +1 more source

Variance estimation for measures of change in probability sampling

, 2003
We propose to estimate the design variance of absolute changes between two cross-sectional estimators under rotating sampling schemes. We show that the variance estimator proposed is generally positive.
Berger, Yves G.
core  

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

Macromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar, Thomas Oliver, Alexander N. Baker   +2 more
wiley   +1 more source

Individual effects and dynamics in count data models [PDF]

, 1999
In this paper we examine the panel data estimation of dynamic models for count data that include correlated fixed effects and predetermined variables. Use of a linear feedback model ls proposed.
Blundell, R., Griffith, R., Windmeijer, F.   +2 more
core  

Inhibition of tau neuronal internalization using anti-tau single domain antibodies

Nature Communications
In Alzheimer’s disease, tau pathology spreads across brain regions as the disease progresses. Intracellular tau can be released and taken up by nearby neurons.
Clément Danis, Elian Dupré, Thomas Bouillet, Marine Denéchaud, Camille Lefebvre, Marine Nguyen, Justine Mortelecque, François-Xavier Cantrelle, Jean-Christophe Rain, Xavier Hanoulle, Morvane Colin, Luc Buée, Isabelle Landrieu   +12 more
doaj   +1 more source

A modified single-domain antibody candidate for the treatment of botulism caused by botulinum toxin type A

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Currently, the primary treatment method for botulism is the use of botulinum antitoxin, which causes a number of side effects, including allergic reactions.
A. A. Derkaev, E. I. Ryabova, I. B. Esmagambetov, D. V. Shcheblyakov, A. N. Noskov, I. D. Vinogradova, V. V. Prokofiev, D. S. Polyansky, D. Y. Logunov, A. L. Gintsburg   +9 more
doaj   +1 more source

VHH Nanobody Versatility against Pentameric Ligand-Gated Ion Channels

Journal of Medicinal Chemistry
Pentameric ligand-gated ion channels provide rapid chemical-electrical signal transmission between cells in the central and peripheral nervous system. Their dysfunction is associated with many nervous system disorders. They are composed of five identical (homomeric receptors) or homologous (heteromeric receptors) subunits.
Dorota Nemecz, Weronika A. Nowak, Ákos Nemecz   +2 more
openaire   +2 more sources

Theory of excitation transfer between two-dimensional semiconductor and molecular layers

, 2017
The geometry-dependent energy transfer rate from an electrically pumped inorganic semiconductor quantum well into an organic molecular layer is studied theoretically.
Bieniek, Björn, Knorr, Andreas, Richter, Marten, Rinke, Patrick, Specht, Judith, Verdenhalven, Eike   +5 more
core   +1 more source