Results 111 to 120 of about 58,013 (257)

Rydberg-London Potential for Diatomic Molecules and Unbonded Atom Pairs

, 2004
We propose and test a pair potential that is accurate at all relevant distances and simple enough for use in large-scale computer simulations. A combination of the Rydberg potential from spectroscopy and the London inverse-sixth-power energy, the ...
Axilrod, Aziz, Aziz, Cheng, Dham, Douketis, Ermler, Ferrante, Hulbert, Kevin Cahill, Klein, Krupenie, Lofthus, Morse, Muto, Rees, Rydberg, Steele, Tang, V. Adrian Parsegian, Varnshi, Viegas, Weissman   +22 more
core   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

PCR detection of hemolysin (vhh) gene in Vibrio harveyi

The Journal of General and Applied Microbiology, 2004
The Vibrio harveyi hemolysin gene (vhh), which encodes for a virulence factor involved in pathogenicity to fish and shellfish species, may be targeted for species detection or strain differentiation. Primers designed for this gene were used in detection studies of V. harveyi strains from various hosts.
Mia Judith U, Conejero, Cynthia T, Hedreyda   +1 more
openaire   +3 more sources

Impact of Interprofessional Simulation on Health Students' Self‐Reported Attitudes Towards Older Adults: A Pre‐Post Questionnaire‐Based Study

European Journal of Dental Education, EarlyView.
ABSTRACT Background Aging simulation may promote the knowledge and skills of healthcare providers and students. We hypothesized that interprofessional simulation related to the care of older adults could influence healthcare students' self‐reported attitudes towards older patients. Materials and Methods Interprofessional role‐play simulations dedicated
Sophie Prissette, Vanessa Bloch, Olivier Bourdon, Sandrine Masseron, Aline Hartmann, Marie‐Violaine Berteretche, Hélène Van Hille, Sophie Leignel, Nejma Batikhy, Teddy Jametal, Adeline Braud   +10 more
wiley   +1 more source

Land reform, poverty reduction and growth : evidence from India [PDF]

, 1998
In recent times there has been a renewed interest in relationships between redistribution, growth and welfare. Land reforms have been central to strategies to improve the asset base of the poor in developing countries thought their effectiveness has been
Besley, Timothy, Burgess, Robin
core  

FVIIIa Mimetics: New Approaches and Next‐Generation Initiatives

Haemophilia, EarlyView.
ABSTRACT Emicizumab has revolutionized hemophilia A care, yet limitations regarding the “ceiling” of hemostatic efficacy (equivalent to mild hemophilia) and global access persist. This review critically examines two distinct paradigms shaping the future of care: Innovation and Access. Regarding innovation, we synthesize the latest clinical data on next‐
Tadashi Matsushita, Keiji Nogami, Chandrakala Shanmukhaiah   +2 more
wiley   +1 more source

A modified single-domain antibody candidate for the treatment of botulism caused by botulinum toxin type A

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Currently, the primary treatment method for botulism is the use of botulinum antitoxin, which causes a number of side effects, including allergic reactions.
A. A. Derkaev, E. I. Ryabova, I. B. Esmagambetov, D. V. Shcheblyakov, A. N. Noskov, I. D. Vinogradova, V. V. Prokofiev, D. S. Polyansky, D. Y. Logunov, A. L. Gintsburg   +9 more
doaj   +1 more source

Biophysical and biochemical characterization of a VHH-based IgG-like bi- and trispecific antibody platform

mAbs, 2020
Here, we report the characterization of a VHH-derived IgG-like bi- and trispecific antibody platform that essentially relies on the replacement of the VH and VL regions of a conventional antibody by two independently functioning VHH domains. Consequently,
Lukas Pekar, Michael Busch, Bernhard Valldorf, Steffen C. Hinz, Lars Toleikis, Simon Krah, Stefan Zielonka   +6 more
doaj   +1 more source

A new catfish species of Microcambeva Costa & Bockmann, 1994 (Siluriformes: Trichomycteridae) from southern Brazil, with a redescription of M. ribeirae Costa, Lima & Bizerril, 2004

Journal of Fish Biology, EarlyView.
Abstract Among the few species of Microcambeva reported as occurring in more than one hydrographic basin, M. ribeirae has been previously listed from both the Ribeira de Iguape and the Guaraqueçaba basins. However, morphological and molecular analyses revealed that the specimens from Guaraqueçaba represent a new species, which is described in this ...
Lucas S. de Medeiros, Igor C. A. Souto‐Santos, Paulo A. Buckup, Juliano Ferrer, Vinicius J. C. Reis, Mario de Pinna, Sergio M. Q. Lima   +6 more
wiley   +1 more source