Results 61 to 70 of about 559 (125)

Ventilator-induced diaphragmatic dysfunction: pathophysiology, monitoring and advances in potential treatment and prevention

European Respiratory Review
Mechanical ventilation is a life-saving method for those critically ill patients with acute or chronic respiratory failure without assistance. However, even short-term mechanical ventilation can lead to alterations in the fibrous structure and reduced ...
Wei Fu, Lili Guan, Qi Liu, Zhefan Xie, Junting You, Rongchang Chen   +5 more
doaj   +1 more source

PINK1/Parkin-mediated mitophagy in mechanical ventilation-induced diaphragmatic dysfunction

Therapeutic Advances in Respiratory Disease, 2021
Background: Mechanical ventilation (MV) often leads to ventilation-induced diaphragm dysfunction (VIDD). Although the development of this disorder had been linked to oxidative stress, mitochondrial energy deficiency, autophagy activation, and apoptosis ...
Hui Yong, Yun Zhou, Wanlin Ye, Tianmei Li, Gangming Wu, Jingyuan Chen, Li Liu, Jicheng Wei   +7 more
doaj   +1 more source

Preferences for pre‐exposure prophylaxis delivery via online pharmacy among potential users in Kenya: a discrete choice experiment

Journal of the International AIDS Society, Volume 27, Issue 10, October 2024.
Abstract Introduction Oral pre‐exposure prophylaxis (PrEP) is highly effective, but coverage remains low in high HIV prevalence settings. Initiating and continuing PrEP remotely via online pharmacies is a promising strategy to expand PrEP uptake, but little is known about potential users’ preferences.
Enrique M. Saldarriaga, Yilin Chen, Michalina A. Montaño, Nicholas Thuo, Catherine Kiptinness, Fern Terris‐Prestholt, Andy Stergachis, Melissa Latigo Mugambi, Kenneth Ngure, Katrina F. Ortblad, Monisha Sharma   +10 more
wiley   +1 more source

Tissue Doppler imaging of the diaphragm and outcome of weaning from mechanical ventilation

Australasian Journal of Ultrasound in Medicine, Volume 27, Issue 3, Page 159-166, August 2024.
Abstract Purpose This study aimed to employ tissue Doppler imaging to monitor diaphragmatic peak velocity and acceleration during contraction and relaxation in mechanically ventilated patients, with the objective of assessing the potential utility of this technique in predicting weaning outcomes.
Shaobo Xin, Yingjia Li, Rui Liu, Xiaozhen Liu, Shaoqing Cai   +4 more
wiley   +1 more source

Mechanical ventilation causes diaphragm dysfunction in newborn lambs

Critical Care, 2019
Background Diaphragm weakness occurs rapidly in adult animals treated with mechanical ventilation (MV), but the effects of MV on the neonatal diaphragm have not been determined.
Feng Liang, Guillaume Emeriaud, Dilson E. Rassier, Dong Shang, Ekaterina Gusev, Sabah N. A. Hussain, Michael Sage, Benjamin Crulli, Etienne Fortin-Pellerin, Jean-Paul Praud, Basil J. Petrof   +10 more
doaj   +1 more source

Diaphragm atrophy during invasive mechanical ventilation is related to extubation failure in preterm infants: An ultrasound study

Pediatric Pulmonology, Volume 59, Issue 4, Page 855-862, April 2024.
Abstract Background Diaphragm dysfunction is associated with poor outcomes in critically ill patients. Ventilator‐induced diaphragmatic dysfunction (VIDD), including diaphragm atrophy (DA), is poorly studied in newborns. We aimed to assess VIDD and its associations in newborns. Methods Single‐center prospective study.
Stefano Nobile, Annamaria Sbordone, Nicola Salce, Maria Letizia Patti, Alessandro Perri, Simona Fattore, Giorgia Prontera, Lucia Giordano, Milena Tana, Giovanni Vento   +9 more
wiley   +1 more source

Ultrasonography to Access Diaphragm Dysfunction and Predict the Success of Mechanical Ventilation Weaning in Critical Care

Journal of Ultrasound in Medicine, Volume 43, Issue 2, Page 223-236, February 2024.
Introduction Weaning failure is common in mechanically ventilated patients, and whether ultrasound (US) can predict weaning outcome remains controversial. This review aims to evaluate the diaphragmatic function measured by US as a predictor of weaning outcome.
Marta Rafael Marques, José Manuel Pereira, José Artur Paiva, Gonzalo García de Casasola‐Sánchez, Yale Tung‐Chen   +4 more
wiley   +1 more source

Hemorrhagic Shock Sensitized the Diaphragm to Ventilator-Induced Dysfunction through the Activation of IL-6/JAK/STAT Signaling-Mediated Autophagy in Rats

Mediators of Inflammation, 2019
Mechanical ventilation (MV) is a major life support technique for the management of trauma-associated hemorrhagic shock (HS). Ventilator-induced diaphragm dysfunction (VIDD), one of the most common complications of MV, has been well demonstrated in ...
Li-Juan Zhang, Shao-Zhou Ni, Xian-Long Zhou, Yan Zhao   +3 more
doaj   +1 more source

Angiotensin-(1–7) exerts a protective action in a rat model of ventilator-induced diaphragmatic dysfunction

Intensive Care Medicine Experimental, 2019
Background Ventilator-induced diaphragmatic dysfunction (VIDD) is a common event during mechanical ventilation (MV) leading to rapid muscular atrophy and contractile dysfunction. Recent data show that renin-angiotensin system is involved in diaphragmatic
Vanessa Zambelli, Anna Sigurtà, Laura Rizzi, Letizia Zucca, Paolo Delvecchio, Elena Bresciani, Antonio Torsello, Giacomo Bellani   +7 more
doaj   +1 more source

Abstracts from HIVR4P 2024, the 5th HIV Research for Prevention Conference, 6 – 10 October, Lima, Peru & Virtual

Journal of the International AIDS Society, Volume 27, Issue S5, October 2024.
wiley   +1 more source