Results 41 to 50 of about 559 (125)

Impact of amino acids on diaphragmatic dysfunction induced by mechanical ventilation:a post⁃hoc analysis of a multicenter,prospective,observational study

open access: yesZhongguo linchuang yanjiu
"Objective To explore the impact of amino acid intake on the occurrence of diaphragmatic dysfunction(VIDD)in patients with mechanical ventilation(MV)exceeding 48 hours. Methods A post⁃hoc analysis of a prospective,multicenter clinical trial was conducted.
ZHAN Yewen*,TANG Can,WU Xiaoxiao,PU Hong
doaj   +1 more source

Ferd og frakt over fjell og vidde

open access: yesPrimitive Tider, 2019
This study demonstrates how routes over mountain plateaus and passes connected farms, hamlets and regions. The routes enabled wide social and economic networks and were a prerequisite for regional surplus production in the Norwegian inland areas from the Viking Age.Iron, furs, skins and antlers were among the important commodities for farmers in the ...
openaire   +4 more sources

Asynchrony Related to Mechanical Ventilation Exacerbates Diaphragm Dysfunction in a Mouse Model of Duchenne Muscular Dystrophy

open access: yesMuscle &Nerve, Volume 74, Issue 1, Page 255-264, July 2026.
ABSTRACT Introduction/Aims In dystrophic mice (mdx, a genetic homolog of Duchenne muscular dystrophy: DMD), previous studies showed that mechanical ventilation (MV) induces ventilator‐induced diaphragmatic dysfunction (VIDD). However, susceptibility to mechanical stress caused by asynchrony remains unknown.
Mohamad Yehya   +7 more
wiley   +1 more source

Impact of Frailty and Diaphragmatic Dysfunction on Outcomes in ARDS: Focusing on Perioperative Respiratory Management

open access: yesThe Clinical Respiratory Journal, Volume 20, Issue 7, July 2026.
This study demonstrates that frailty and diaphragmatic dysfunction independently and synergistically increase mortality risk in ARDS patients, with concurrent conditions amplifying 28‐day mortality to 55.6%. A combined CFS‐DTF‐APACHE II predictive model (AUC = 0.851–0.889) effectively identifies high‐risk patients, supporting routine integration of ...
Mengmei Ma   +5 more
wiley   +1 more source

0546 : Mitochondrial induced oxidative stress triggers Ca2+-dependent proteolysis and underlie VIDD

open access: yesArchives of Cardiovascular Diseases Supplements, 2016
Rationale In rodents, prolonged controlled mechanical ventilation (CMV) and associated diaphragm inactivity elicits complex pathologic changes referred to as ventilator-induced diaphragm dysfunction (VIDD). Previous workers have demonstrated that VIDD is characterized by increased mitochondrial generation of reactive oxygen species (ROS) and redox ...
openaire   +1 more source

Ventilator-Induced Diaphragm Dysfunction (Review)

open access: yesОбщая реаниматология, 2018
Mechanical ventilation is associated with a number of complications that increase the cost of treatment and the hospital mortality rate. In 2004, the term «ventilator-induced diaphragm dysfunction» (VIDD) was proposed to explain one of the reasons for ...
M. A. Babaev   +4 more
doaj   +1 more source

Diaphragmatic Ultrasonography as a Predictor of Extubation Success in Children: Systematic Review and Meta‐Analysis

open access: yesPediatric Pulmonology, Volume 61, Issue 2, February 2026.
ABSTRACT Background This study aimed to determine the diagnostic accuracy of the Diaphragmatic Thickening Fraction (DTF) and Diaphragmatic Excursion (DE) in predicting extubation success. Methods This study was a systematic review with meta‐analysis of observational studies.
Diego Santos de Oliveira   +3 more
wiley   +1 more source

Altered expression of microRNAs in the rat diaphragm in a model of ventilator-induced diaphragm dysfunction after controlled mechanical ventilation

open access: yesBMC Genomics, 2021
Background Ventilator-induced diaphragm dysfunction (VIDD) is a common complication of life support by mechanical ventilation observed in critical patients in clinical practice and may predispose patients to severe complications such as ventilator ...
Pengcheng Wang   +5 more
doaj   +1 more source

Targeting heat shock proteins mitigates ventilator induced diaphragm muscle dysfunction in an age-dependent manner

open access: yesFrontiers in Physiology, 2016
Intensive care unit (ICU) patients are often overtly subjected to mechanical ventilation and immobilization, which leads to impaired limb and respiratory muscle function.
Hannah Ogilvie   +5 more
doaj   +1 more source

Multi-omics reveals age-related differences in the diaphragm response to mechanical ventilation: a pilot study

open access: yesSkeletal Muscle, 2021
Background Old age is associated with a significantly increased mortality in COVID-19 patients exposed to long-term controlled mechanical ventilation (CMV) and suggested to be due to the hyperinflammatory response associated with the viral infection ...
Qiong Lyu   +5 more
doaj   +1 more source

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