Results 31 to 40 of about 559 (125)

Recovery of diaphragm function following mechanical ventilation in a rodent model. [PDF]

PLoS ONE, 2014
BACKGROUND: Mechanical ventilation (MV) induces diaphragmatic muscle fiber atrophy and contractile dysfunction (ventilator induced diaphragmatic dysfunction, VIDD).
Christian S Bruells, Ingmar Bergs, Rolf Rossaint, Jun Du, Christian Bleilevens, Andreas Goetzenich, Joachim Weis, Michael P Wiggs, Scott K Powers, Marc Hein   +9 more
doaj   +1 more source

Coagulation and fibrinolysis in hyperparathyroidism secondary to vitamin D deficiency

Endocrinology, Diabetes & Metabolism Case Reports, 2018
Introduction: Abnormal coagulation tests have been observed in patients with primary hyperparathyroidism (HPT) suggesting a prothrombotic effect of parathyroid hormone (PTH). Vitamin D deficiency (VIDD) is the most frequent cause of secondary HPT. Aim of
Laura P B Elbers, Marije Wijnberge, Joost C M Meijer, Dennis C W Poland, Dees P M Brandjes, Eric Fliers, Victor E A Gerdes   +6 more
doaj   +1 more source

Diaphragm dysfunction induced by mechanical ventilation – pathophysiology and treatment options [PDF]

Liječnički vjesnik, 2022
Majority of mechanically ventilated patients in intensive care units (ICU) suffer from diaphragm dysfunction. It occurs in approximately 60 to 80 % of such patients.
Iva Pažur, Josipa Kovačić, Ognjen Ožegić   +2 more
doaj   +1 more source

Imaging of the Diaphragm Following Cardiac Surgery: Focus on Ultrasonographic Assessment

Journal of Ultrasound in Medicine, Volume 42, Issue 11, Page 2481-2490, November 2023., 2023
Diaphragm dysfunction is a common complication following cardiac surgery. Its clinical impact is variable, ranging from the absence of symptoms to the acute respiratory failure. Post‐operative diaphragm dysfunction may negatively affect patients' prognosis delaying the weaning from the mechanical ventilation (MV), extending the time of hospitalization ...
Vincenzo Rizza, Francesco Maranta, Lorenzo Cianfanelli, Iside Cartella, Ottavio Alfieri, Domenico Cianflone   +5 more
wiley   +1 more source

Ventilator-induced diaphragm dysfunction: translational mechanisms lead to therapeutical alternatives in the critically ill

Intensive Care Medicine Experimental, 2019
Mechanical ventilation [MV] is a life-saving technique delivered to critically ill patients incapable of adequately ventilating and/or oxygenating due to respiratory or other disease processes.
Oscar Peñuelas, Elena Keough, Lucía López-Rodríguez, Demetrio Carriedo, Gesly Gonçalves, Esther Barreiro, José Ángel Lorente   +6 more
doaj   +1 more source

Maintenance of spontaneous breathing at an intensity of 60%-80% may effectively prevent mechanical ventilation-induced diaphragmatic dysfunction.

PLoS ONE, 2020
Controlled mechanical ventilation (CMV) can cause diaphragmatic motionlessness to induce diaphragmatic dysfunction. Partial maintenance of spontaneous breathing (SB) can reduce ventilation-induced diaphragmatic dysfunction (VIDD). However, to what extent
Zujin Luo, Silu Han, Wei Sun, Yan Wang, Sijie Liu, Liu Yang, Baosen Pang, Jiawei Jin, Hong Chen, Zhixin Cao, Yingmin Ma   +10 more
doaj   +1 more source

Identification of the co-differentially expressed hub genes involved in the endogenous protective mechanism against ventilator-induced diaphragm dysfunction

Skeletal Muscle, 2022
Background In intensive care units (ICU), mechanical ventilation (MV) is commonly applied to save patients’ lives. However, ventilator-induced diaphragm dysfunction (VIDD) can complicate treatment by hindering weaning in critically ill patients and ...
Dong Zhang, Wenyan Hao, Qi Niu, Dongdong Xu, Xuejiao Duan   +4 more
doaj   +1 more source

Endoplasmic Reticulum Stress Contributes to Ventilator-Induced Diaphragm Atrophy and Weakness in Rats

Frontiers in Physiology, 2022
Background: Accumulating evidence indicates that endoplasmic reticulum (ER) stress plays a critical role in the regulation of skeletal muscle mass. In recent years, much attention has been given to ventilator-induced diaphragm dysfunction (VIDD) because ...
Shaoping Li, Guanguan Luo, Rong Zeng, Lian Lin, Xingnan Zou, Yu Yan, Haoli Ma, Jian Xia, Yan Zhao, Xianlong Zhou   +9 more
doaj   +1 more source

Lung-protective ventilation worsens ventilator-induced diaphragm atrophy and weakness

Respiratory Research, 2020
Background Lung–protective ventilation (LPV) has been found to minimize the risk of ventilator–induced lung injury (VILI). However, whether LPV is able to diminish ventilator–induced diaphragm dysfunction (VIDD) remains unknown.
Xian-Long Zhou, Xiao-Jun Wei, Shao-Ping Li, Hao-Li Ma, Yan Zhao   +4 more
doaj   +1 more source

Increased SOD2 in the diaphragm contributes to exercise-induced protection against ventilator-induced diaphragm dysfunction

Redox Biology, 2019
Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, prolonged MV results in rapid diaphragmatic atrophy and contractile dysfunction, collectively termed ventilator-induced diaphragm dysfunction (VIDD)
Aaron B. Morton, Ashley J. Smuder, Michael P. Wiggs, Stephanie E. Hall, Bumsoo Ahn, J. Matthew Hinkley, Noriko Ichinoseki-Sekine, Andres Mor Huertas, Mustafa Ozdemir, Toshinori Yoshihara, Nicholas R. Wawrzyniak, Scott K. Powers   +11 more
doaj   +1 more source