Adesão, proliferação e migração de células de astrocitoma humano U-87 em fibronectina, laminina e colágeno IV e a expressão e organização de vimentina e GFAP [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasO microambiente extracelular é capaz de modular a organização e expressão dos filamentos intermediários (vimentina ...
Garcez, Ricardo Castilho
core
Reconstitution of intermediate-sized filaments from denatured monomeric vimentin
Vimentin, a major cytoskeletal protein of many cells of mesenchymal tissues as well as of cultured cells of various kinds, is the constituent protein of a special class of intermediate-sized (7 to 11 nm) filaments.
Franke , W. +5 more
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Intermediate Filaments in Motion: Observations of Intermediate Filaments in Cells Using Green Fluorescent Protein-Vimentin [PDF]
In the movies presented in this essay we have demonstrated that IFs are dynamic in nature. Movements of IFs include both extension and retraction and are dependent on the presence of intact MTs. Furthermore, we have characterized a possible intermediate of IF turnover, IF fragments.
J L, Martys +3 more
openaire +2 more sources
Intermediate Filaments at the Junction of Mechanotransduction, Migration, and Development
Mechanically induced signal transduction has an essential role in development. Cells actively transduce and respond to mechanical signals and their internal architecture must manage the associated forces while also being dynamically responsive.
Rucha Sanghvi-Shah, Gregory F. Weber
doaj +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin [PDF]
The cornified envelope is a layer of transglutaminase cross-linked protein that is assembled under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Christiana Ruhrberg +7 more
core +1 more source
Vimentin intermediate filaments undergo irreversible conformational changes during cyclic loading
Intermediate filaments (IFs) are part of the cytoskeleton of eukaryotic cells and, therefore, are largely responsible for the cell's mechanical properties.
Janshoff, Andreas +9 more
core +3 more sources
Withaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivo. [PDF]
Type I collagen is the most abundant protein in the human body. Its excessive synthesis results in fibrosis of various organs. Fibrosis is a major medical problem without an existing cure.
Azariyas A Challa +3 more
doaj +1 more source
Abstract BACKGROUND Diet‐induced inflammation is a major cause of muscle degeneration impacting human and animal health. Owing to their anti‐inflammatory and antioxidant properties, polyphenols have attracted considerable interest as feed additives.
Graziella Orso +8 more
wiley +1 more source
Deciphering vimentin assembly: Bridging theoretical models and experimental approaches
: The intricate assembly process of vimentin intermediate filaments (IFs), key components of the eukaryotic cytoskeleton, has yet to be elucidated.
Soyeon Jeong, Nam-Chul Ha
doaj +1 more source

