Results 61 to 70 of about 900,097 (207)

Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division

Nature Communications, 2019
The intermediate filament vimentin reorganizes during mitosis, but its molecular regulation and impact on the cell during cell division is unclear. Here, the authors show that vimentin filaments redistribute to the cell cortex during mitosis intertwining
Sofia Duarte, Álvaro Viedma-Poyatos, Elena Navarro-Carrasco, Alma E. Martínez, María A. Pajares, Dolores Pérez-Sala   +5 more
doaj   +1 more source

Testicular Localization and Potential Function of Vimentin Positive Cells during Spermatogonial Differentiation Stages

Animals, 2022
Vimentin is a type of intermediate filament (IF) and one of the first filaments expressed in spermatogenesis. Vimentin plays numerous roles, consisting of the determination of cell shape, differentiation, cell motility, the maintenance of cell junctions,
Amirreza Niazi Tabar, Hossein Azizi, Danial Hashemi Karoii, Thomas Skutella   +3 more
doaj   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

Advanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz, Matthieu Gelin, Lucas Pradeau‐Phélut, Arrate Muñoz‐Barrutia, Sandrine Etienne‐Manneville, Daniel Garcia‐Gonzalez   +5 more
wiley   +1 more source

Mechanics of Intermediate Filaments [PDF]

, 2014
The eukariotic cytoskeleton consists of three major filament types: actin filaments, microtubules and intermediate filaments. While the first two filament types are highly conserved, intermediate filaments vary between cell types.
Nöding, Bernd
core   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Morphological, histochemical and immunohistochemical studies of polar fox kidney

Folia Histochemica et Cytobiologica, 2012
The aim of the present study was to evaluate the morphology and intermediate filaments cytokeratin, desmin and vimentin expression in the kidneys of the polar fox (<em>Alopex lagopus</em>).
Wiesław Skrzypczak, Katarzyna Piotrowska, Sylwia Słuczanowska-Głąbowska, Marcin Wylot, Roman Szymeczko, Maria Laszczyńska, Małgorzata Ożgo   +6 more
doaj   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA. [PDF]

J Cell Sci, 2017
The actin and intermediate filament cytoskeletons contribute to numerous cellular processes, including morphogenesis, cytokinesis and migration. These two cytoskeletal systems associate with each other, but the underlying mechanisms of this interaction ...
Jiu Y, Peränen J, Schaible N, Cheng F, Eriksson JE, Krishnan R, Lappalainen P.   +6 more
europepmc   +2 more sources

Vimentin Intermediate Filament Rings Deform the Nucleus During the First Steps of Adhesion

Frontiers in Cell and Developmental Biology, 2019
During cell spreading, cells undergo many changes to their architecture and their mechanical properties. Vimentin, as an integral part of the cell architecture, and its mechanical stability must adapt to the new state of the cell.
Emmanuel Terriac, Susanne Schütz, Franziska Lautenschläger, Franziska Lautenschläger   +3 more
doaj   +1 more source

Sacsin Deletion Induces Aggregation of Glial Intermediate Filaments

Cells, 2022
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disorder commonly diagnosed in infants and characterized by progressive cerebellar ataxia, spasticity, motor sensory neuropathy and axonal demyelination.
Fernanda Murtinheira, Mafalda Migueis, Ricardo Letra-Vilela, Mickael Diallo, Andrea Quezada, Cláudia A. Valente, Abel Oliva, Carmen Rodriguez, Vanesa Martin, Federico Herrera   +9 more
doaj   +1 more source