Results 51 to 60 of about 900,097 (207)
Tension Causes Unfolding of Intracellular Vimentin Intermediate Filaments [PDF]
Advanced Biosystems, 2020 Abstract Intermediate filament (IF) proteins are a class of proteins that constitute different filamentous structures in mammalian cells. As such, IF proteins are part of the load‐bearing cytoskeleton and support the nuclear envelope.
Frederik Fleissner +7 more
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The intermediate filament protein, vimentin, is a regulator of NOD2 activity [PDF]
Gut, 2012 Objective Mutations in the nucleotide-binding oligomerisation domain-containing protein 2 (NOD2) gene remain the strongest genetic determinants for Crohn's disease (CD). Having previously identified vimentin as a novel NOD2-interacting protein, the authors aimed to investigate the ...
Craig, Stevens +8 more
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Vimentin intermediate filaments in cancer cells [PDF]
, 2023 Introducere. Cancerul este una dintre cele mai grave și răspândite boli. Cercetările în domeniul histopatologiei cancerului joacă un rol important în căutarea unor noi metode de diagnostic, tratament și prevenire a acestei patologii.
Mitcov, Maxim
core +1 more source
PLoS ONE, 2011 Quantitative imaging of intermediate filaments (IF) during the advanced phase of the assembly process is technically difficult, since the structures are several µm long and therefore they exceed the field of view of many electron (EM) or atomic force ...
Stefan Winheim +7 more
doaj +1 more source
In vitro translation of the intermediate filament proteins desmin and vimentin. [PDF]
Molecular and Cellular Biology, 1981 Polyadenylated ribonucleic acid (RNA) was isolated from chicken skeletal and smooth muscle and translated in a cell-free rabbit reticulocyte system. Both types of muscle tissue contain messenger RNAs that code for the intermediate filament proteins desmin and vimentin, and the relative concentrations of the two translation products reflect the ...
C M, O'Connor +3 more
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Fragmentation and Entanglement Limit Vimentin Intermediate Filament Assembly
Physical Review X, 2022 Networks of intermediate filaments (IFs) need to constantly reorganize to fulfil their functions at different locations within the cell. The mechanism of IF assembly is well described and involves filament end-to-end annealing. By contrast, the mechanisms involved in IF disassembly are far less understood. In vitro
Tran, Quang +4 more
openaire +3 more sources
Vimentin Diversity in Health and Disease
Cells, 2018 Vimentin is a protein that has been linked to a large variety of pathophysiological conditions, including cataracts, Crohn’s disease, rheumatoid arthritis, HIV and cancer.
Frida Danielsson +4 more
doaj +1 more source
Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion
Cell Adhesion & Migration, 2021 Atypical protein kinase C (aPKC) are involved in progression of many human cancers. Vimentin is expressed during epithelial to mesenchymal transition (EMT). Molecular dynamics of Vimentin intermediate filaments (VIFs) play a key role in metastasis.
Wishrawana S. Ratnayake +5 more
doaj +1 more source
Cells, 2022 Airway smooth muscle cell migration plays a role in the progression of airway remodeling, a hallmark of allergic asthma. However, the mechanisms that regulate cell migration are not yet entirely understood.
Ruping Wang +4 more
doaj +1 more source
Nanomechanics of vimentin intermediate filament networks
Soft Matter, 2010 Intermediate filaments are one of three classes of fibrous proteins in the cytoskeleton of eukaryotes, the others being actin filaments and microtubules. The dense filamentous networks and bundles provide important mechanical stability for the cell. Here we directly measure both the structure and mechanical properties of an in vitro model system for ...
Köster, Sarah +3 more
openaire +2 more sources