Results 31 to 40 of about 900,097 (207)

Hierarchical structure controls nanomechanical properties of vimentin intermediate filaments. [PDF]

PLoS ONE, 2009
Intermediate filaments (IFs), in addition to microtubules and microfilaments, are one of the three major components of the cytoskeleton in eukaryotic cells, playing a vital role in mechanotransduction and in providing mechanical stability to cells ...
Zhao Qin, Laurent Kreplak, Markus J Buehler   +2 more
doaj   +1 more source

Direct observation of subunit exchange along mature vimentin intermediate filaments. [PDF]

Biophys J, 2014
Actin filaments, microtubules, and intermediate filaments (IFs) are central elements of the metazoan cytoskeleton. At the molecular level, the assembly mechanism for actin filaments and microtubules is fundamentally different from that of IFs. The former
Nöding B, Herrmann H, Köster S.
europepmc   +2 more sources

Stiffening and inelastic fluidization in vimentin intermediate filament networks [PDF]

Soft Matter, 2019
Nonlinear shear rheology reveals that intermediate filaments balance two contradictory roles: mechanoprotection by stiffening and dynamic cellular processes through softening.
Anders Aufderhorst-Roberts, Gijsje H. Koenderink   +1 more
openaire   +3 more sources

The role of vimentin intermediate filaments in cortical and cytoplasmic mechanics. [PDF]

Biophys J, 2013
The mechanical properties of a cell determine many aspects of its behavior, and these mechanics are largely determined by the cytoskeleton. Although the contribution of actin filaments and microtubules to the mechanics of cells has been investigated in great detail, relatively little is known about the contribution of the third major cytoskeletal ...
Guo M, Ehrlicher AJ, Mahammad S, Fabich H, Jensen MH, Moore JR, Fredberg JJ, Goldman RD, Weitz DA.   +8 more
europepmc   +4 more sources

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis [PDF]

, 2005
Several kinases phosphorylate vimentin, the most common intermediate filament protein, in mitosis. Aurora-B and Rho-kinase regulate vimentin filament separation through the cleavage furrow-specific vimentin phosphorylation.
Erich A. Nigg, Andreas Uldschmid, Hanisch, Anja, Uldschmid, Andreas, Takashi Oguri, Takai, Yasushi, Tomoya Yamaguchi, Yasushi Takai, Masaki Inagaki, Goto, Hidemasa, Tomoya Yokoyama, Anja Hanisch, Hidemasa Goto, Silljé, Herman, Herman Silljé, Oguri, Takashi, Yamaguchi, Tomoya, Nigg, Erich A., Inagaki, Masaki, Yokoyama, Tomoya   +19 more
core   +1 more source

Coil 2 of intermediate filaments: its complete structure and impact of desminopathy-related mutations. [PDF]

, 2011
The eukaryotic cytoskeleton consists of three major filamentous networks. The thinnest filament network of about 6 nm diameter is made up of globular actin subunits, whereas the thicker microtubule network of about 22 nm diameter contains 13 ...
Nicolet, Stefan
core   +1 more source

Characterization of cells of amniotic fluids by immunological identification of intermediate-sized filaments: Presence of cells of different tissue origin [PDF]

, 1981
Antibodies against intermediate-sized filaments, of the prekeratin or vimentin type, were used to investigate the presence of these filaments by indirect immunofluorescence microscopy in cultured and non-cultured amniotic fluid cells, in frozen sections ...
Cremer, Thomas, Treiss, I., Cremer, Marion, Franke, W. W., Hager, D.   +4 more
core   +1 more source

DYNAMICS OF INTERMEDIATE FILAMENT PROTEIN EXPRESSION IN THE BUFFALO UTERUS DURING THE FOLLICULAR AND LUTEAL PHASE OF THE ESTROUS CYCLE [PDF]

Exploratory Animal and Medical Research
Laminin and vimentin are two intermediate filaments that play a pivotal role in uterine cellular proliferation, differentiation, maintaining cellular integrity or stability, receptivity, and the implantation process.
Sagarika Dehury
doaj   +1 more source

Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

Redox Biology, 2019
The intermediate filament protein vimentin constitutes a critical sensor for electrophilic and oxidative stress, which induce extensive reorganization of the vimentin cytoskeletal network.
Andreia Mónico, Sofia Duarte, María A. Pajares, Dolores Pérez-Sala   +3 more
doaj   +1 more source

Withania somnifera Root Extract Inhibits Mammary Cancer Metastasis and Epithelial to Mesenchymal Transition [PDF]

, 2013
Though clinicians can predict which patients are at risk for developing metastases, traditional therapies often prove ineffective and metastatic disease is the primary cause of cancer patient death; therefore, there is a need to develop anti-metastatic ...
Adam I. Marcus, Songli Xu (457629), Anapatricia Garcia (457628), Paula M. Vertino (457631), Klymkowsky, Michael, Doris R Powell, Marcus Adam I., Vertino, PM, Anapatricia Garcia, Shivendra Singh (457632), Singh Shivendra, Yang, Zhen, Doris R. Powell (457630), Paula M Vertino, Garcia Anapatricia, Vertino Paula M., Singh, Shivendra, Paula M. Vertino, Adam I Marcus, Marcus, Adam I., Garcia, A, Powell, DR, Shivendra Singh, Singh, S, Zhen Yang (107412), Powell, Doris R., Zhen Yang, Yang, Z, Yang Zhen, Vertino, Paula M., Songli Xu, Xu, S, Garcia, Anapatricia, Xu, Songli, Doris R. Powell, Zhen Yang, Adam I. Marcus (457633), Powell Doris R., Marcus, AI, Xu Songli   +39 more
core   +2 more sources