Results 51 to 60 of about 447,313 (350)

BK polyomavirus diversity—Why viral variation matters

Reviews in Medical Virology, 2020
SummaryBK polyomavirus (BKPyV or BKV) is a non‐enveloped, circular double‐stranded DNA virus that may exceed 80% seroprevalence in adults. BKV infection typically occurs during childhood, and the majority of adults are latently infected. While BKV infection is rarely associated with clinical disease in most individuals, in immunosuppressed individuals,
Jason T. Blackard, Stella M. Davies, Benjamin L. Laskin   +2 more
openaire   +3 more sources

Viral Metagenomics Reveals Widely Diverse Viral Community of Freshwater Amazonian Lake

Frontiers in Public Health, 2022
Despite the importance of understanding the ecology of freshwater viruses, there are not many studies on the subject compared to marine viruses. The microbiological interactions in these environments are still poorly known, especially between bacteriophages and their host bacteria and between cyanophages and cyanobacteria.
Wylerson Guimarães Nogueira, Bruna Verônica Azevedo Gois, Kenny da Costa Pinheiro, Andressa de Oliveira Aragão, Ana Lídia Cavalcante Queiroz, Artur Luiz da Silva, Adriana Carneiro Folador, Rommel Thiago Jucá Ramos   +7 more
openaire   +3 more sources

Viral Diversity in Autochthonous Croatian Grapevine Cultivars [PDF]

Plant Disease, 2017
A survey was conducted on nine autochthonous grapevine cultivars grown along the Croatian coastal region. In total, 48 vines (44 from germplasm collection, 4 from vineyards) originating from 23 sites were tested for 26 viruses using molecular methods. Results revealed high infection rates with Grapevine leafroll-associated virus 3 (GLRaV-3); Grapevine
Vončina, Darko, Al Rwahnih, Maher, Rowhani, Adib, Gouran, Mona, Almeida, Rodrigo PP   +4 more
openaire   +4 more sources

RNA Viruses in Aquatic Ecosystems through the Lens of Ecological Genomics and Transcriptomics

Viruses, 2022
Massive amounts of data from nucleic acid sequencing have changed our perspective about diversity and dynamics of marine viral communities. Here, we summarize recent metatranscriptomic and metaviromic studies targeting predominantly RNA viral communities.
Sandra Kolundžija, Dong-Qiang Cheng, Federico M. Lauro   +2 more
doaj   +1 more source

Correlations in the T Cell Response to Altered Peptide Ligands

, 2004
The vertebrate immune system is a wonder of modern evolution. Occasionally, however, correlations within the immune system lead to inappropriate recruitment of preexisting T cells against novel viral diseases.
Arstila, Bachmann, Bachmann, Blattman, Bogarad, Chandler, Deem, Derrida, Derrida, Drossel, Garboczi, Garcia, Jeong-Man Park, Kauffman, Kedl, Kesmir, Klenerman, Lee, Lee, Martin, Michael W. Deem, Perelson, Perelson, Schodin, Singh, Sloan-Lancaster, Sourdive   +26 more
core   +1 more source

Viral population estimation using pyrosequencing [PDF]

, 2008
The diversity of virus populations within single infected hosts presents a major difficulty for the natural immune response as well as for vaccine design and antiviral drug therapy.
A Dempster, A Rambaut, AMN Tsibris, B Gaschen, Baback Gharizadeh, C Wang, Chunlin Wang, D O'Meara, DC Douek, E Domingo, E Halperin, EH Simpson, ES Lander, Glenn Tesler, GS Gottlieb, GW Tyson, H Fakhrai-Rad, I Malet, IM Rouzine, J Kececioglu, JE Hopcroft, JF Simons, K Chen, KJ Metzner, L Bacheler, L Doukhan, L Excoffier, Lior Pachter, LR Ford, M Breitbart, M Eigen, M Margulies, M Stephens, MA Nowak, MJ Gonzales, ML Collins, ML Sogin, Mostafa Ronaghi, MT Tammi, N Beerenwinkel, Nicholas Eriksson, Niko Beerenwinkel, P Jenkins, PA Pevzner, R Schmid, R Shankarappa, Robert W. Shafer, RP Dilworth, S Huse, S-Y Rhee, S-Y Rhee, Soo-Yon Rhee, VA Johnson, Yumi Mitsuya   +53 more
core   +7 more sources

Non‐invasive surveys of mammalian viruses using environmental DNA

Methods in Ecology and Evolution, 2021
Environmental DNA (eDNA) and invertebrate‐derived DNA (iDNA) are used to survey biodiversity non‐invasively to mitigate difficulties in obtaining wildlife samples, particularly in remote areas or for rare species. Recently, eDNA/iDNA were used to monitor
Niccolò Alfano, Anisha Dayaram, Jan Axtner, Kyriakos Tsangaras, Marie‐Louise Kampmann, Azlan Mohamed, Seth T. Wong, M. Thomas P. Gilbert, Andreas Wilting, Alex D. Greenwood   +9 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Diversity of viral photosystem-I psaA genes [PDF]

The ISME Journal, 2014
Abstract Marine photosynthesis is one of the major contributors to the global carbon cycle and the world’s oxygen supply. This process is largely driven by cyanobacteria, namely Synechococcus and Prochlorococcus. Genes encoding photosystem-II (PSII) reaction center proteins are found in many cyanophage genomes, and are expressed during ...
Gur Hevroni, Hagay Enav, Forest Rohwer, Oded Béjà   +3 more
openaire   +3 more sources

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source