Results 1 to 10 of about 484,497 (156)

B Cell Receptor's function in virus entry: Anti-SARS-CoV-2 B cell receptors can mediate viral entry in an ACE2-independent mechanism. [PDF]

PLoS Pathogens
B cells play a crucial role in humoral immunity, acting as sentinels against viral infections by using their B cell receptors (BCRs) to recognize viral proteins.
Rene Larios, Md Belal Hossain, Rebecca Brown, Arjit Vijey Jeyachandran, Angel Elma Abu, Anne Kathrin Zaiss, Christina M Ramirez, Masakazu Kamata, Steve Cole, Ting-Ting Wu, Kenneth Dorshkind, Vaithilingaraja Arumugaswami, Kouki Morizono   +12 more
doaj   +2 more sources

Viral entry shapes HCMV latency establishment [PDF]

Nature Communications
Human cytomegalovirus (HCMV) infection results in either productive or latent infection, the latter enabling life-long viral persistence. Monocytes support latent infection but become permissive to productive infection upon differentiation into ...
Yaarit Kitsberg, Aharon Nachshon, Tamar Arazi, Karin Broennimann, Tal Fisher, Alexander Wainstein, Yaara Finkel, Noam Stern-Ginossar, Michal Schwartz   +8 more
doaj   +2 more sources

SLC38A9 regulates SARS-CoV-2 viral entry [PDF]

iScience
Summary: SARS-CoV-2 viral entry into host cells depends on the cleavage of spike (S) protein into S1 and S2 proteins. Such proteolytic cleavage by furin results in the exposure of a multibasic motif on S1, which is critical for SARS-CoV-2 viral infection
Gaurav Datta, Neda Rezagholizadeh, Wendie A. Hasler, Nabab Khan, Xuesong Chen   +4 more
doaj   +2 more sources

mGem: The complexity of viral entry—one virus, many receptors [PDF]

mBio
Binding to cellular receptors initiates viral replication and dictates sites in the host infected by the virus. As illustrated by mammalian orthoreovirus (reovirus), viruses can bind several types of receptors using distinct capsid components to ...
Terence S. Dermody, Danica M. Sutherland
doaj   +2 more sources

The Role of Orthobunyavirus Glycoprotein Gc in the Viral Life Cycle: From Viral Entry to Egress [PDF]

Molecules
Orthobunyavirus refers to the virus members within the Genus Orthobunyavirus, which is the largest virus genus in the Family Peribunyaviridae and even Class Bunyaviricetes.
Han Gao, Dengshuai Zhao, Canyuan Li, Menghua Deng, Gan Li, Shengfeng Chen, Mengmeng Zhao, Limei Qin, Keshan Zhang   +8 more
doaj   +2 more sources

To Include or Occlude: Rational Engineering of HCV Vaccines for Humoral Immunity

Viruses, 2021
Direct-acting antiviral agents have proven highly effective at treating existing hepatitis C infections but despite their availability most countries will not reach the World Health Organization targets for elimination of HCV by 2030.
Felicia Schlotthauer, Joey McGregor, Heidi E Drummer   +2 more
doaj   +1 more source

The Viral Capsid: A Master Key to Access the Host Nucleus

Viruses, 2021
Viruses are pathogens that have evolved to hijack the cellular machinery to replicate themselves and spread to new cells. During the course of evolution, viruses developed different strategies to overcome the cellular defenses and create new progeny ...
Guillermo Blanco-Rodriguez, Francesca Di Nunzio   +1 more
doaj   +1 more source

Blocking entry of hepatitis B and D viruses to hepatocytes as a novel immunotherapy for treating chronic infections [PDF]

, 2021
Background. Chronic hepatitis B and D virus (HBV/HDV) infections can cause cancer. Current HBV therapy using nucleoside analogues (NAs) is life-long and reduces but does not eliminate the risk of cancer.
Ahlén, G, Frelin, L, Jagya, N, Johansson, M, Maravelia, P, Meuleman, Philip, Ni, Y, Pasetto, A, Pater, L, Pérez, NC, Sällberg, M, Urban, S, Verch, G, Verhoye, Lieven   +13 more
core   +1 more source

Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents [PDF]

, 2014
Hepatitis C virus (HCV) is transmitted between hepatocytes via classical cell entry but also uses direct cell-cell transfer to infect neighboring hepatocytes.
A Owsianka, A Sigal, Aleem Siddiqui, Arvind H. Patel, AS Lok, AW Tarr, B Bartolini, B Sainz Jr, C Hezode, C Lee, C Nathan, C Sarrazin, CL Brimacombe, CM Lange, CT Jones, D Masson, D Trono, EJ Gane, Eric Soulier, F Kuonen, F Poordad, F Poordad, Fei Xiao, François Habersetzer, G Koutsoudakis, H Kwon, H Yan, H Zhu, Heidi Barth, I Fofana, I Fofana, I Fofana, IA Abela, IM Jacobson, Isabel Fofana, J Grove, J Lupberger, J Witteveldt, J Zhong, Jens Bukh, JG McHutchison, JM Gottwein, JM Gottwein, JM Pawlotsky, JM Pawlotsky, JM Pawlotsky, JM Timpe, L Rong, L Zona, Laura Heydmann, LW Meredith, MB Zeisel, MB Zeisel, Michel Doffoël, Mirjam B. Zeisel, MN Zahid, MS Sulkowski, MT Catanese, N Shi, O Lenz, P Zhong, PM Trembling, Q Sattentau, S Haid, T Pietschmann, T Pietschmann, T Wakita, Thomas F. Baumert, TJ Liang, TK Scheel, V Soriano, VD Cataldo, ZY Keck   +72 more
core   +16 more sources

The Process of Filopodia Induction during HPV Infection

Viruses, 2022
Human Papillomavirus 16 (HPV16) infects mucosal and epithelial cells and has been identified as a high-risk HPV type that is an etiologic agent of human cancers.
Alyssa Biondo, Patricio I. Meneses
doaj   +1 more source