Membranotropic peptides mediating viral entry [PDF]
Peptide Science, 2018 The means used by enveloped viruses to bypass cellular membranes are well characterized; however, the mechanisms used by non‐enveloped viruses to deliver their genome inside the cell remain unresolved and poorly defined.
A. Falanga +3 more
semanticscholar +4 more sources
Viral entry and the ubiquitin‐proteasome system [PDF]
Cellular Microbiology, 2020 Viruses confiscate cellular components of the ubiquitin‐proteasome system (UPS) to facilitate many aspects of the infectious cycle. The 26S proteasome is an ATP‐dependent, multisubunit proteolytic machine present in all eukaryotic cells.
Seth M. Schneider +2 more
semanticscholar +3 more sources
TRIM32 inhibits Venezuelan equine encephalitis virus infection by targeting a late step in viral entry. [PDF]
PLoS PathogXie Y +9 more
europepmc +3 more sources
To Include or Occlude: Rational Engineering of HCV Vaccines for Humoral Immunity
Viruses, 2021 Direct-acting antiviral agents have proven highly effective at treating existing hepatitis C infections but despite their availability most countries will not reach the World Health Organization targets for elimination of HCV by 2030.
Felicia Schlotthauer +2 more
doaj +1 more source
Nature Communications, 2023 Patients with cystic fibrosis are not reporting particularly sever outcomes upon SARS-CoV-2 infection. Here, the authors demonstrate decreased ACE2 levels is cystic fibrosis airway epithelia associated with impaired viral entry and replication.
V. Bezzerri +21 more
semanticscholar +1 more source
The Viral Capsid: A Master Key to Access the Host Nucleus
Viruses, 2021 Viruses are pathogens that have evolved to hijack the cellular machinery to replicate themselves and spread to new cells. During the course of evolution, viruses developed different strategies to overcome the cellular defenses and create new progeny ...
Guillermo Blanco-Rodriguez +1 more
doaj +1 more source
An Aquareovirus Exploits Membrane-Anchored HSP70 To Promote Viral Entry
Microbiology spectrum, 2023 The seasonality of viral diseases in ectotherms is a prevailing phenomenon in the aquatic environment, which causes huge economic losses every year worldwide and hinders sustainable development of the aquaculture industry. Nevertheless, our understanding
Guoli Hou +11 more
semanticscholar +1 more source
Blocking entry of hepatitis B and D viruses to hepatocytes as a novel immunotherapy for treating chronic infections [PDF]
, 2021 Background. Chronic hepatitis B and D virus (HBV/HDV) infections can cause cancer. Current HBV therapy using nucleoside analogues (NAs) is life-long and reduces but does not eliminate the risk of cancer.
Ahlén, G +13 more
core +1 more source
Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]
, 2011 Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Geraghty, R.J. +5 more
core +12 more sources
Antigen identification and high-throughput interaction mapping by reprogramming viral entry
Nature Methods, 2021 Deciphering immune recognition is critical for understanding a broad range of diseases and for the development of effective vaccines and immunotherapies.
C. Dobson +11 more
semanticscholar +1 more source