Results 11 to 20 of about 484,497 (156)

Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration

open access: yeseLife, 2020
The Spike protein of SARS-CoV-2, its receptor-binding domain (RBD), and its primary receptor ACE2 are extensively glycosylated. The impact of this post-translational modification on viral entry is yet unestablished.
Qi Yang   +8 more
doaj   +1 more source

Membrane Rafts: Portals for Viral Entry

open access: yesFrontiers in Microbiology, 2021
Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to the lifecycle of different viral families including virus entry, assembly ...
Inés Ripa   +7 more
doaj   +1 more source

Monitoring Viral Entry in Real-Time Using a Luciferase Recombinant Vesicular Stomatitis Virus Producing SARS-CoV-2, EBOV, LASV, CHIKV, and VSV Glycoproteins

open access: yesViruses, 2020
Viral entry is the first stage in the virus replication cycle and, for enveloped viruses, is mediated by virally encoded glycoproteins. Viral glycoproteins have different receptor affinities and triggering mechanisms.
Maria Fernanda Lay Mendoza   +4 more
doaj   +1 more source

Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. [PDF]

open access: yes, 2011
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) emerged as the causal agent of an endemic atypical pneumonia, infecting thousands of people worldwide.
Agudelo, Juliet   +10 more
core   +1 more source

SARS-CoV-2 Spike Glycoprotein and ACE2 Interaction Reveals Modulation of Viral Entry in Wild and Domestic Animals

open access: yesFrontiers in Medicine, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a viral pathogen causing life-threatening diseases in humans. Interaction between the spike protein of SARS-CoV-2 and angiotensin-converting enzyme 2 (ACE2) is a potential factor in the ...
Manas Ranjan Praharaj   +14 more
doaj   +1 more source

Keratinocyte differentiation-dependent human papillomavirus gene regulation [PDF]

open access: yes, 2017
Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive cancers. HPVs infect epithelial cells and their replication cycle is tightly linked with the differentiation process of the infected keratinocyte.
Graham, Sheila V.
core   +1 more source

An aquatic virus exploits the IL6-STAT3-HSP90 signaling axis to promote viral entry.

open access: yesPLoS Pathogens, 2023
Viral seasonality in the aquaculture industry is an important scientific issue for decades. While the molecular mechanisms underpinning the temperature-dependent pathogenesis of aquatic viral diseases remain largely unknown.
Guoli Hou   +13 more
doaj   +1 more source

Caveolin-1 Associated Adenovirus Entry into Human Corneal Cells [PDF]

open access: yes, 2014
The cellular entry of viruses represents a critical area of study, not only for viral tropism, but also because viral entry dictates the nature of the immune response elicited upon infection.
Chintakuntlawar, Ashish V.   +7 more
core   +1 more source

Surfactant protein D inhibits HIV-1 infection of target cells via interference with gp120-CD4 interaction and modulates pro-inflammatory cytokine production [PDF]

open access: yes, 2014
© 2014 Pandit et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Al-Mozaini, MA   +12 more
core   +7 more sources

Caveolin-1 associated adenovirus entry into human corneal cells. [PDF]

open access: yesPLoS ONE, 2013
The cellular entry of viruses represents a critical area of study, not only for viral tropism, but also because viral entry dictates the nature of the immune response elicited upon infection.
Mohammad A Yousuf   +7 more
doaj   +1 more source

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