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Gut, 2020 Objective Since December 2019, a newly identified coronavirus (severe acute respiratory syndrome coronavirus (SARS-CoV-2)) has caused outbreaks of pneumonia in Wuhan, China.
Hao Zhang +13 more
semanticscholar +1 more source
Keratinocyte differentiation-dependent human papillomavirus gene regulation [PDF]
, 2017 Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive cancers. HPVs infect epithelial cells and their replication cycle is tightly linked with the differentiation process of the infected keratinocyte.
Graham, Sheila V.
core +1 more source
Viral entry mechanisms: the increasing diversity of paramyxovirus entry [PDF]
The FEBS Journal, 2009 The paramyxovirus family contains established human pathogens such as the measles virus and human respiratory syncytial virus, as well as emerging pathogens including the Hendra and Nipah viruses and the recently identified human metapneumovirus. Two major envelope glycoproteins, the attachment protein and the fusion protein, promote the processes of ...
Everett C, Smith +4 more
openaire +2 more sources
Virology Journal, 2018 Background Human enterovirus 71 (EV71) was previously known to enter cells through clathrin or caveolar mediated endocytic pathways. However, we observed chlorpromazine (CPZ) or dynasore (DNS), which inhibit clathrin and dynamin mediated endocytosis, did
Meichun Yuan +10 more
doaj +1 more source
Caveolin-1 Associated Adenovirus Entry into Human Corneal Cells [PDF]
, 2014 The cellular entry of viruses represents a critical area of study, not only for viral tropism, but also because viral entry dictates the nature of the immune response elicited upon infection.
Chintakuntlawar, Ashish V. +7 more
core +1 more source
PLoS Pathogens, 2020 Coronaviruses recognize a variety of receptors using different domains of their envelope-anchored spike protein. How these diverse receptor recognition patterns affect viral entry is unknown.
J. Shang +9 more
semanticscholar +1 more source
VPS29 Exerts Opposing Effects on Endocytic Viral Entry [PDF]
mBio, 2021 These data identify a host pathway by which VPS29 and associated factors control the endosomal environment in a manner that influences susceptibility to viral infection. This pathway could serve as a pharmaceutical target for intervention in zoonotic viral diseases, including those caused by coronaviruses, influenza viruses, and filoviruses, all of ...
Daniel Poston +3 more
openaire +3 more sources
Respiratory Syncytial Virus Entry Inhibitors Targeting the F Protein
Viruses, 2013 Human respiratory syncytial virus (RSV) is the main viral cause of respiratory tract infection in infants as well as some elderly and high-risk adults with chronic pulmonary disease and the severely immunocompromised.
Shibo Jiang +3 more
doaj +1 more source
Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection [PDF]
, 2017 Type I IFNs promote cellular responses to viruses, and IFN receptor (IFNAR) signaling regulates the responses of endothelial cells of the blood-brain barrier (BBB) during neurotropic viral infection.
Ali +23 more
core +3 more sources
Antiviral lectins: Selective inhibitors of viral entry
Antiviral Research, 2017 Many natural lectins have been reported to have antiviral activity. As some of these have been put forward as potential development candidates for preventing or treating viral infections, we have set out in this review to survey the literature on antiviral lectins.
C. Mitchell, K. Ramessar, B. O’Keefe
semanticscholar +3 more sources