Results 61 to 70 of about 2,155,361 (380)
Lipid Tales of Viral Replication and Transmission. [PDF]
Trends in Cell Biology, 2017 Positive-strand RNA viruses are the largest group of RNA viruses on Earth and cellular membranes are critical for all aspects of their life cycle, from entry and replication to exit. In particular, membranes serve as platforms for replication and as carriers to transmit these viruses to other cells, the latter either as an envelope surrounding a single
N. Altan-Bonnet
semanticscholar +4 more sources
Stress Granules in the Viral Replication Cycle [PDF]
Viruses, 2011 As intracellular parasites, viruses require a host cell in order to replicate. However, they face a series of cellular responses against infection. One of these responses is the activation of the double-stranded RNA (dsRNA)-activated protein kinase R (PKR). PKR phosphorylates the α subunit of eukaryotic translation initiation factor 2 (eIF2α), which in
Hilda Montero, Vicenta Trujillo-Alonso
openaire +4 more sources
Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA
Nature Communications, 2018 APOBEC3G (A3G) is a single-stranded DNA (ssDNA) cytidine deaminase that restricts HIV-1. Here the authors provide molecular insights into A3G substrate recognition by determining the 1.86 Å resolution crystal structure of its catalytic domain bound to ...
Atanu Maiti +7 more
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UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication. [PDF]
PLoS Pathogens, 2017 Positive-strand RNA virus infections can induce the stress-related unfolded protein response (UPR) in host cells. This study found that enterovirus A71 (EVA71) utilizes host UDP-glucose glycoprotein glucosyltransferase 1 (UGGT1), a key endoplasmic ...
Peng-Nien Huang +5 more
doaj +1 more source
Infection of human cytomegalovirus in cultured human gingival tissue. [PDF]
, 2006 BackgroundHuman cytomegalovirus (HCMV) infection in the oral cavity plays an important role in its horizontal transmission and in causing viral-associated oral diseases such as gingivitis.
Chu, Alice +5 more
core +3 more sources
Zika NS1–induced ER remodeling is essential for viral replication
Journal of Cell Biology, 2019 Zika virus induces the formation of vesicles from ER membrane that form viral replication factories in the ER lumen. Ci et al. show that the Zika NS1 protein plays a key role in this remodeling of the ER as the insertion of the hydrophobic regions of NS1
Y. Ci +8 more
semanticscholar +1 more source
Viral dew: Phase separation and the formation of viral replication compartments
PLOS Pathogens, 2023 PLoS pathogens 19(2), e1011145 - (2023).
Jens B. Bosse, Wolfram Brune
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Mutations in the C-terminus of HBoV NS1 affect the function of NP1
Scientific Reports, 2017 Human bocavirus 1 (HBoV1) is an autonomous parvovirus in the Bocaparvovirus genus. The multifunctional nuclear protein NP1 is involved in viral replication.
Junmei Zhang +6 more
doaj +1 more source
PLoS ONE, 2012 Although HCMV encodes many genes required for the replication of its DNA genome, no HCMV-encoded orthologue of the origin binding protein, which has been identified in other herpesviruses, has been identified.
Tamara Evans Braun +2 more
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FUSE binding protein FUBP3 is a potent regulator in Japanese encephalitis virus infection
Virology Journal, 2021 Background The JEV genome is a positive-sense RNA with a highly structured capped 5′UTR, 3′UTR and a large open reading frame. 3′UTR is the untranslated region of flavivirus and has various important functions during viral replication, such as ...
Peng Xu, Wei Tong, Young-Mao Chen
doaj +1 more source