Formation of large viroplasms and virulence of Cauliflower mosaic virus in turnip plants depend on the N-terminal EKI sequence of viral protein TAV. [PDF]
PLoS ONE, 2017 Cauliflower mosaic virus (CaMV) TAV protein (TransActivator/Viroplasmin) plays a pivotal role during the infection cycle since it activates translation reinitiation of viral polycistronic RNAs and suppresses RNA silencing.
Angèle Geldreich +8 more
doaj +4 more sources
Development of Nanobodies against Mal de Río Cuarto virus major viroplasm protein P9-1 for diagnostic sandwich ELISA and immunodetection [PDF]
Scientific Reports, 2021 Mal de Río Cuarto virus (MRCV) is a member of the genus Fijivirus of the family Reoviridae that causes a devastating disease in maize and is persistently and propagatively transmitted by planthopper vectors.
Gabriela Llauger +10 more
doaj +3 more sources
Requirements of Rotavirus Viroplasm Formation in Species A to J [PDF]
Rotavirus (RV) is a major cause of severe gastroenteritis in infants and young children. It causes an estimated 128'000 deaths annually, mainly in low- and middle-income countries.
Lee, Melissa Carina
core +2 more sources
Rotavirus Particle Disassembly and Assembly In Vivo and In Vitro. [PDF]
Viruses, 2023 Rotaviruses (RVs) are non-enveloped multilayered dsRNA viruses that are major etiologic agents of diarrheal disease in humans and in the young in a large number of animal species.
Asensio-Cob D, Rodríguez JM, Luque D.
europepmc +3 more sources
Rotavirus Viroplasm Proteins Interact with the Cellular SUMOylation System: Implications for Viroplasm-Like Structure Formation [PDF]
Journal of Virology, 2013 ABSTRACT Posttranslational modification by SUMO provides functional flexibility to target proteins. Viruses interact extensively with the cellular SUMO modification system in order to improve their replication, and there are numerous examples of viral proteins that are SUMOylated.
M. Campagna +10 more
openaire +3 more sources
Rice black-streaked dwarf virus P6 self-interacts to form punctate, viroplasm-like structures in the cytoplasm and recruits viroplasm-associated protein P9-1 [PDF]
Virology Journal, 2011 Abstract Background Rice black-streaked dwarf virus (RBSDV), a member of the genus Fijivirus within the family Reoviridae, can infect several graminaceous plant species including rice, maize and wheat, and is transmitted by planthoppers.
Yu Jialin +6 more
openaire +3 more sources
Development of a minigenome cassette for Lettuce necrotic yellows virus: A first step in rescuing a plant cytorhabdovirus [PDF]
, 2020 Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta ...
Drake, P +3 more
core +1 more source
Liquid-liquid phase separation is essential for reovirus viroplasm formation and immune evasion. [PDF]
J VirolABSTRACT Grass carp reovirus (GCRV) is the most virulent pathogen in the genus Aquareovirus , belonging to the family Spinareoviridae . Members of the Spinareoviridae family are known to replicate and assemble in ...
He L +9 more
europepmc +3 more sources
Coordination of Zika Virus Infection and Viroplasm Organization by Microtubules and Microtubule-Organizing Centers. [PDF]
Cells, 2021 Zika virus (ZIKV) became a global health concern in 2016 due to its links to congenital microcephaly and other birth defects. Flaviviruses, including ZIKV, reorganize the endoplasmic reticulum (ER) to form a viroplasm, a compartment where virus particles are assembled.
Buchwalter RA +11 more
europepmc +5 more sources
Defensive‐lipid droplets: Cellular organelles designed for antimicrobial immunity
Immunological Reviews, Volume 317, Issue 1, Page 113-136, August 2023., 2023 Summary Microbes have developed many strategies to subvert host organisms, which, in turn, evolved several innate immune responses. As major lipid storage organelles of eukaryotes, lipid droplets (LDs) are an attractive source of nutrients for invaders.
Rémi Safi +5 more
wiley +1 more source