Results 111 to 120 of about 4,749 (194)
Viroporins and inflammasomes: A key to understand virus-induced inflammation
The International Journal of Biochemistry & Cell Biology, 2020 Viroporins are virus encoded proteins that alter membrane permeability and can trigger subsequent cellular signals. Oligomerization of viroporin subunits results in formation of a hydrophilic pore which facilitates ion transport across host cell membranes.
Farag, N.S. +3 more
openaire +2 more sources
Hepatology Research, Volume 54, Issue 8, Page 1-30, August 2024.Abstract Acute hepatitis E was considered rare until reports emerged affirming the existence of hepatitis E virus (HEV) genotypes 3 and 4 infections in Japan in the early 2000s. Extensive studies by Japanese researchers have highlighted the pivotal role of pigs and wild animals, such as wild boars and deer, as reservoirs for HEV, linking them to ...
Tatsuo Kanda +48 more
wiley +1 more source
Frontiers in Microbiology, 2020 Classical swine fever (CSF) is a highly contagious viral disease causing severe economic losses to the swine industry. As viroporins of viruses modulate the cellular ion balance and then take over the cellular machinery, blocking the activity of ...
Jindai Fan +41 more
doaj +1 more source
Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma [PDF]
, 2017 Hepatitis C virus (HCV) infection is one of the leading causes of hepatocellular carcinoma (HCC) worldwide but the mechanistic basis as to how chronic HCV infection furthers the HCC process remains only poorly understood.
Fuhler, G.M. (Gwenny) +4 more
core +1 more source
Journal of Medical Virology, Volume 96, Issue 7, July 2024.Abstract Antiviral signaling, immune response and cell metabolism are dysregulated by SARS‐CoV‐2, the causative agent of COVID‐19. Here, we show that SARS‐CoV‐2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10 induce a significant mitochondrial and metabolic reprogramming in A549 lung epithelial cells.
Blanca D. López‐Ayllón +22 more
wiley +1 more source
The minimalist architectures of viroporins and their therapeutic implications
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2014 Many viral genomes encode small, integral membrane proteins that form homo-oligomeric channels in membrane, and they transport protons, cations, and other molecules across the membrane barrier to aid various steps of viral entry and maturation. These viral proteins, collectively named viroporins, are crucial for viral pathogenicity.
OuYang, Bo, Chou, James J.
openaire +2 more sources
Annals of the New York Academy of Sciences, Volume 1535, Issue 1, Page 31-41, May 2024.Abstract In 2023, the Keystone Symposia held the first international scientific conference convening research leaders investigating the pathology of post‐acute sequelae of COVID‐19 (PASC) or Long COVID, a growing and urgent public health priority.
Matthew S. Durstenfeld +5 more
wiley +1 more source
Plant-derived antivirals against hepatitis c virus infection [PDF]
, 2018 Hepatitis C virus (HCV) infection is a worldwide public health burden and it is estimated that 185 million people are or have previously been infected worldwide.
Harris, M +3 more
core +1 more source
The Human Polyoma JC Virus Agnoprotein Acts as a Viroporin
PLoS Pathogens, 2010 Virus infections can result in a range of cellular injuries and commonly this involves both the plasma and intracellular membranes, resulting in enhanced permeability. Viroporins are a group of proteins that interact with plasma membranes modifying permeability and can promote the release of viral particles.
Suzuki, Tadaki +8 more
openaire +5 more sources
Review on the role of the human Polyomavirus JC in the development of tumors [PDF]
, 2017 Almost one fifth of human cancers worldwide are associated with infectious agents, either bacteria or viruses, and this makes the possible association between infections and tumors a relevant research issue.
Manola Comar +2 more
core +1 more source