Results 121 to 130 of about 4,749 (194)
Hepatitis C: From inflammatory pathogenesis to anti-inflammatory/hepatoprotective therapy [PDF]
, 2018 Hepatitis C virus (HCV) infection commonly causes progressive liver diseases that deteriorate from chronic inflammation to fibrosis, cirrhosis and even to hepatocellular carcinoma.
Huang, Meng-Hao +3 more
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Review of current cell-penetrating antibody developments for HIV-1 therapy [PDF]
, 2018 The discovery of highly active antiretroviral therapy (HAART) in 1996 has significantly reduced the global mortality and morbidity caused by the acquired immunodeficiency syndrome (AIDS).
Muhamad Alif Che Nordin, +1 more
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Immune mechanisms of vaccine induced protection against chronic hepatitis C virus infection in chimpanzees [PDF]
, 2015 Hepatitis C virus (HCV) infection is characterized by a high propensity for development of life-long viral persistence. An estimated 170 million people suffer from chronic hepatitis caused by HCV.
Boonstra, P.A. (André) +2 more
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Regulation of hepatitis C virus replication via threonine phosphorylation of the NS5A protein
, 2018 The hepatitis C virus non-structural 5A (NS5A) protein is highly phosphorylated and plays roles in both virus genome replication and assembly of infectious virus particles. NS5A comprises three domains separated by low complexity sequences (LCS).
Douglas Ross-Thriepland +4 more
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Viroporin Activity of the Foot-and-Mouth Disease Virus Non-Structural 2B Protein.
PLoS ONE, 2015 Viroporins are a family of low-molecular-weight hydrophobic transmembrane proteins that are encoded by various animal viruses. Viroporins form transmembrane pores in host cells via oligomerization, thereby destroying cellular homeostasis and inducing ...
Da Ao +10 more
doaj +1 more source
Viroporin-mediated Membrane Permeabilization [PDF]
Journal of Biological Chemistry, 2002 Aitziber Agirre +3 more
openaire +1 more source
Investigation of Molecular Mechanism of JC virus Viroporin Activity
Uirusu, 2015 Viroporins are small and hydrophobic viral proteins that form pores on host cell membranes, and their expression can increase the permeability of cellular membranes and the production of progeny virus particles. JC virus (JCV) is the causative agent of progressive multifocal leukoenchephalopathy (PML).
openaire +3 more sources
Scientific Reports, 2017 The structure of the p7 viroporin, an oligomeric membrane protein ion channel involved in the assembly and release of the hepatitis C virus, was determined from proteins expressed and inserted directly into supported model lipid membranes using cell-free
Thomas Soranzo +3 more
doaj +1 more source
, 2010 Porcine reproductive and respiratory syndrome (PRRS) is an economically devastating viral disease affecting the swine industry worldwide. The etiological agent, PRRS virus (PRRSV), possesses a RNA viral genome with nine open reading frames (ORFs).
Albina +46 more
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Recent advances in pharmaceutical sciences VII [PDF]
, 2017 The E-book series Recent Advances in Pharmaceutical Sciences reports research contributions from different areas of the multidisciplinary field of Pharmaceutical Sciences.
Feliu José, Carlos +2 more
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