Results 41 to 50 of about 13,721 (179)

Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis

mBio, 2022
Bordetella produces an array of virulence factors, including the adenylate cyclase toxin (ACT), which is essential, immunogenic in humans, and highly conserved.
Andrea M. DiVenere, Dzifa Amengor, Rui P. Silva, Jory A. Goldsmith, Jason S. McLellan, Jennifer A. Maynard   +5 more
doaj   +1 more source

Protection against pertussis in humans correlates to elevated serum antibodies and memory B cells [PDF]

, 2017
Pertussis is a respiratory infection caused by Bordetella pertussis that may be particularly severe and even lethal in the first months of life when infants are still too young to be vaccinated. Adults and adolescents experience mild symptoms and are the
Carsetti, Rita, Di Mattia, G., Fedele, Giorgio, Frassanito, A., Gesualdo, Francesco, Leone, Pasqualina, Marcellini, Valentina, Midulla, Fabio, Mortari, Eva Piano, Nenna, R., Pandolfi, Elisabetta, Stefanelli, Paola, The Pertussis Study, Gropu, Tozzi, Alberto Eugenio   +13 more
core   +1 more source

Virulence Associated Gene 8 of Bordetella pertussis Enhances Contact System Activity by Inhibiting the Regulatory Function of Complement Regulator C1 Inhibitor

Frontiers in Immunology, 2018
Bordetella pertussis is a Gram-negative bacterium and the causative agent of whooping cough. Whooping cough is currently re-emerging worldwide and, therefore, still poses a continuous global health threat. B. pertussis expresses several virulence factors
Elise S. Hovingh, Elise S. Hovingh, Steven de Maat, Alexandra P. M. Cloherty, Steven Johnson, Elena Pinelli, Coen Maas, Ilse Jongerius, Ilse Jongerius   +8 more
doaj   +1 more source

Genome characterization and population genetic structure of the zoonotic pathogen, streptococcus canis [PDF]

, 2012
Background - Streptococcus canis is an important opportunistic pathogen of dogs and cats that can also infect a wide range of additional mammals including cows where it can cause mastitis. It is also an emerging human pathogen.
Lang, P., Lefébure, T., Moroni, P., Pavinski Bitar, P.D., Richards, V.P., Stanhope, M.J., Tikofsky, L., Werner, B., Zadoks, R.N.   +8 more
core   +5 more sources

Molecular aspects of Bordetella pertussis pathogenesis [PDF]

, 2010
The molecular mechanisms of Bordetella virulence are now well understood, and many virulence factors have been identified and characterized at the molecular level.
Camille Locht
core   +2 more sources

Genetic relatedness and antimicrobial susceptibility of porcine respiratory tract pathogens Streptococcus suis, Bordetella bronchiseptica and Pasteurella multocida [PDF]

, 2019
Streptococcus suis is a Gram-positive bacterium and a commensal colonizing the porcine respiratory tract. However, some serotypes have a higher virulence and can cause pneumonia, meningitis, septicaemia, arthritis, endocarditis, polyserositis or abortion
Niemann, Lisa
core   +1 more source

From Lake Victoria to the Tap: Antibiotic Resistance and Pathogenic Contamination of Kisumu City Water Supply and Wastewater Network

Tropical Medicine &International Health, EarlyView.
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva, Anthony Sifuna, Francis Orata, Caroline Omolo, Jacob Stanley Iramiot, Mark C. Enright, Awelani Mutshembele, Jian Zhou, William A. Shivoga   +8 more
wiley   +1 more source

BopN is a Gatekeeper of the Bordetella Type III Secretion System

Microbiology Spectrum, 2023
The classical Bordetella species infect the respiratory tract of mammals. While B. bronchiseptica causes rather chronic respiratory infections in a variety of mammals, the human-adapted species B. pertussis and B.
Kevin Munoz Navarrete, Ladislav Bumba, Tatyana Prudnikova, Ivana Malcova, Tania Romero Allsop, Peter Sebo, Jana Kamanova   +6 more
doaj   +1 more source

Clinical and computed tomography findings of fatal poxviral vasculitis in a domestic shorthair cat

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract This report describes the clinical presentation, haematological abnormalities and imaging findings of systemic poxvirus infection in a cat that resulted in widespread severe dermal oedema and systemic inflammatory response syndrome. The cat lacked cutaneous lesions before the onset of dermal oedema, but developed crusting skin lesions and a ...
Mica Taylor, Harriet R. Hall, Hannah Wong, Lorraine Peschard, Emanuele Ricci, Katie E. McCallum   +5 more
wiley   +1 more source

PTX Instructs the Development of Lung-Resident Memory T Cells in Bordetella pertussis Infected Mice

Toxins, 2021
Whooping cough is a severe, highly contagious disease of the human respiratory tract, caused by Bordetellapertussis. The pathogenicity requires several virulence factors, including pertussis toxin (PTX), a key component of current available vaccines ...
Julie Tomas, Yoon Koo, Dimitri Popoff, Vilma Arce-Gorvel, Sean Hanniffy, Jean-Pierre Gorvel, Cyrille Mionnet   +6 more
doaj   +1 more source