Results 61 to 70 of about 13,721 (179)

A Deep Metagenomic Snapshot as a Proof‐of‐Concept for Resource Generation: Simultaneous Assembly of Host, Food, and Microbiome Genomes From Stingless Bee Larval Food

Ecology and Evolution, Volume 15, Issue 12, December 2025.
This study serves as a proof‐of‐concept, demonstrating that deep shotgun sequencing of a single complex sample—stingless bee larval food—can simultaneously generate multiple genomic resources. From this dataset, we assembled three genomes (a near‐complete bacterium, a draft host mitochondrion, and a fragmented plant chloroplast) with varying ...
Carlos Ueira‐Vieira, Ana Carolina Costa Santos, Thayane Nogueira Araújo, Solange Cristina Augusto, Natanael Borges de Avila, Ana Maria Bonetti, Anderson Rodrigues dos Santos   +6 more
wiley   +1 more source

The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model.

PLoS Pathogens, 2022
Pulmonary infections caused by Bordetella pertussis used to be the prime cause of infant mortality in the pre-vaccine era and mouse models of pertussis pneumonia served in characterization of B. pertussis virulence mechanisms.
Jana Holubova, Ondrej Stanek, Attila Juhasz, Illiassou Hamidou Soumana, Peter Makovicky, Peter Sebo   +5 more
doaj   +1 more source

Contribution of fibronectin-binding protein to pathogenesis of Streptococcus suis serotype 2 [PDF]

, 2002
In the present study we investigated the role of the fibronectin (FN)- and fibrinogen (FGN)-binding protein (FBPS) in the pathogenesis of Streptococcus suis serotype 2 in piglets. The complete gene encoding FBPS from S.
Greeff, A., de, Buys, H., Verhaar, R., Dijkstra, J., Alphen, L., van, Smit, H.E.   +5 more
core   +2 more sources

Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]

, 2020
The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
core   +2 more sources

Phylogeny, Synteny, and Distribution of Type III Secretion Systems in Burkholderia cenocepacia: A Closer Look Into Host Span

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
T3SS is a dedicated machinery that mediates interactions between bacteria and eukaryotic cells, providing a functional interface in pathogenic or symbiotic associations. Phylogenetic analyses and T3SS‐gene synteny revealed nine gene clusters, with no needle protein gene (sctF). However, an orphan CDS encoding a putative SctF was found.
Gabrielle Tomé Cordeiro, Hadassa Loth de Oliveira, Danielly C. O. Mariano, Yasmin Salazar Torres, Graciela Maria Dias, Bianca C. Neves   +5 more
wiley   +1 more source

Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates

Toxins, 2017
Bordetella pertussis and Bordetella parapertussis are the causal agents of whooping cough in humans. They produce diverse virulence factors, including adenylate cyclase-hemolysin (AC-Hly), a secreted toxin of the repeat in toxins (RTX) family with ...
Valérie Bouchez, Thibaut Douché, Mélody Dazas, Sophie Delaplane, Mariette Matondo, Julia Chamot-Rooke, Nicole Guiso   +6 more
doaj   +1 more source

The Bordetella Secreted Regulator BspR Is Translocated into the Nucleus of Host Cells via Its N-Terminal Moiety: Evaluation of Bacterial Effector Translocation by the Escherichia coli Type III Secretion System. [PDF]

PLoS ONE, 2015
Bordetella bronchiseptica is genetically related to B. pertussis and B. parapertussis, which cause respiratory tract infections in humans. These pathogens possess a large number of virulence factors, including the type III secretion system (T3SS), which ...
Akio Abe, Ryutaro Nishimura, Naomichi Tanaka, Jun Kurushima, Asaomi Kuwae   +4 more
doaj   +1 more source

Analysis of Bordetella pertussis populations in European countries with different vaccination policies. [PDF]

, 2005
Despite the widespread use of pertussis vaccines during the last decades, pertussis has remained an endemic disease with frequent epidemic outbreaks. Currently two types of vaccines are used: whole-cell vaccines (WCVs) and recently developed acellular ...
Amersfoorth, S C M van, Schouls, L M, Heide, H G J van der, Advani, A, Hallander, H O, Bondeson, K, König, C H W von, Riffelmann, M, Vahrenholz, C, Guiso, N, Caro, V, Njamkepo, E, He, Q, Mertsola, J, Mooi, F R   +14 more
core   +1 more source

Rebound of Respiratory Virus Activity and Seasonality to Pre‐Pandemic Patterns

Journal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT The emergence of SARS‐CoV‐2 and the implementation of non‐pharmaceutical interventions (NPIs) profoundly disrupted the transmission dynamics of respiratory viruses, altering their epidemiology and seasonality. However, comprehensive long‐term data on these shifts and their post‐pandemic implications remain limited.
Rainer Gosert, Klaudia Naegele, Marvin Weiss, Roland Bingisser, Christian H. Nickel, Jakob Meyer, Martin Siegemund, Stefano Bassetti, Sarah Dräger, Christoph T. Berger, Fabian Franzek, Ulrich Heininger, Julia Bielicki, Hans H. Hirsch, Peter M. Keller, Maja Weisser, Nina Khanna, Sarah Tschudin‐Sutter, Karoline Leuzinger   +18 more
wiley   +1 more source

New Data on Vaccine Antigen Deficient Bordetella pertussis Isolates

Vaccines, 2015
Evolution of Bordetella pertussis is driven by natural and vaccine pressures. Isolates circulating in regions with high vaccination coverage present multiple allelic and antigenic variations as compared to isolates collected before introduction of ...
Valérie Bouchez, Nicolas Hegerle, Francesco Strati, Elisabeth Njamkepo, Nicole Guiso   +4 more
doaj   +1 more source