Programmable polymorphism of a virus-like particle [PDF]
Communications Materials, 2022 Virus-like particles are promising for drug delivery systems and vaccine development, but controlling their size and morphology is challenging. Here, amino acid sequences are inserted into MS2 bacteriophage virus-like particles, with their size and shape
Artur P. Biela +4 more
doaj +8 more sources
Virus-like Particle Vaccines and Platforms for Vaccine Development [PDF]
Viruses, 2023 Virus-like particles (VLPs) have gained a lot of interest within the past two decades. The use of VLP-based vaccines to protect against three infectious agents—hepatitis B virus, human papillomavirus, and hepatitis E virus—has been approved; they are ...
Milad Kheirvari +2 more
doaj +3 more sources
Virus-like particle vaccinology, from bench to bedside [PDF]
Cellular & Molecular Immunology, 2022 Virus-like particles (VLPs) have become key tools in biology, medicine and even engineering. After their initial use to resolve viral structures at the atomic level, VLPs were rapidly harnessed to develop antiviral vaccines followed by their use as ...
Mona O. Mohsen, Martin F. Bachmann
semanticscholar +3 more sources
Versatile virus-like particle carrier for epitope based vaccines. [PDF]
PLoS ONE, 2010 BACKGROUND: Recombinant proteins and in particular single domains or peptides are often poorly immunogenic unless conjugated to a carrier protein. Virus-like-particles are a very efficient means to confer high immunogenicity to antigens.
Alain C Tissot +9 more
doaj +21 more sources
Zika virus-like particle (VLP) based vaccine. [PDF]
PLoS Neglected Tropical Diseases, 2017 The newly emerged mosquito-borne Zika virus poses a major public challenge due to its ability to cause significant birth defects and neurological disorders.
Hélène Boigard +5 more
doaj +2 more sources
Preclinical Development of a Novel Zika Virus-like Particle Vaccine in Combination with Tetravalent Dengue Virus-like Particle Vaccines [PDF]
VaccinesDeclared as a Public Health Emergency in 2016 by the World Health Organization (WHO), the Zika virus (ZIKV) continues to cause outbreaks that are linked to increased neurological complications.
Dominik A. Rothen +12 more
doaj +2 more sources
Translation of the L-species dsRNA genome of the killer-associated virus-like particles of Saccharomyces cerevisiae [PDF]
, 1977 Virus-like particles containing the L (P1)-species of double-stranded RNA (dsRNA) were isolated from Saccharomyces cerevisiae, and the translational activity of the virus-like particle-derived dsRNA was analyzed in the wheat germ cell-free system ...
Bostian, Keith A. +3 more
core +3 more sources
Virus-like Particle (VLP) Vaccines for Cancer Immunotherapy. [PDF]
Int J Mol Sci, 2023 Cancer vaccines are increasingly being studied as a possible strategy to prevent and treat cancers. While several prophylactic vaccines for virus-caused cancers are approved and efficiently used worldwide, the development of therapeutic cancer vaccines ...
Ruzzi F +8 more
europepmc +3 more sources
Asymmetrical Flow Field-Flow Fractionation on Virus and Virus-Like Particle Applications [PDF]
Microorganisms, 2019 Asymmetrical flow field-flow fractionation (AF4) separates sample components based on their sizes in the absence of a stationary phase. It is well suited for high molecular weight samples such as virus-sized particles.
K. Eskelin, M. Poranen, H. M. Oksanen
semanticscholar +6 more sources
Virus-Like Particle, Liposome, and Polymeric Particle-Based Vaccines against HIV-1
Frontiers in Immunology, 2018 It is acknowledged that vaccines remain the best hope for eliminating the HIV-1 epidemic. However, the failure to produce effective vaccine immunogens and the inability of conventional delivery strategies to elicit the desired immune responses remains a ...
Yong Gao +2 more
doaj +2 more sources