Results 21 to 30 of about 583,625 (325)
Self diffusion of particles in complex fluids: temporary cages and permanent barriers [PDF]
, 2008 We study the self diffusion of individual particles in dense (non-)uniform complex fluids within dynamic density functional theory and explicitly account for their coupling to the temporally fluctuating background particles. Applying the formalism to rod-
H. Risken +6 more
core +5 more sources
The 3Ds in virus‐like particle based‐vaccines: “Design, Delivery and Dynamics”
Immunological Reviews, 2020 Vaccines need to be rationally designed in order be delivered to the immune system for maximizing induction of dynamic immune responses. Virus‐like particles (VLPs) are ideal platforms for such 3D vaccines, as they allow the display of complex and native
Mona O. Mohsen, G. Augusto, M. Bachmann
semanticscholar +1 more source
A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]
, 2012 Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Corey W. Hecksel +6 more
core +12 more sources
Virology Journal, 2023 Vaccine efficacy of conventional influenza vaccines depend on the antigenic similarity between the selected vaccine strain and annual epidemic strain. Since the influenza virus evolves yearly, a vaccine which is independent from viral antigenic mutation ...
Toshifumi Imagawa +4 more
doaj +1 more source
The potential for reassortment between Oropouche and Schmallenberg Orthobunyaviruses [PDF]
, 2017 A number of viruses within the Peribunyaviridae family are naturally occurring reassortants, a common phenomenon for segmented viruses. Using a minigenome-reporter and virus-like particle (VLP) production assay, we have accessed the potential of ...
Elliott, Richard M. +3 more
core +1 more source
Antibody Opsonization of a TLR9 Agonist–Containing Virus-like Particle Enhances In Situ Immunization
Journal of Immunology, 2020 Key Points Immunostimulation by CMP-001 requires anti-Qβ Ab. In mice, IT CMP-001 induces lymphoma regression that is enhanced by anti–PD-1. The immunologic and therapeutic effects of intratumoral (IT) delivery of a novel virus-like particle as a lymphoma
Caitlin D. Lemke-Miltner +6 more
semanticscholar +1 more source
Vaccines, 2021 Capsid-like particle (CLP) displays can be used to enhance the immunogenicity of vaccine antigens, but a better understanding of how CLP vaccines are best formulated and delivered is needed.
Christoph M. Janitzek +10 more
doaj +1 more source
Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies [PDF]
, 2016 There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and
Callewaert, Nico +9 more
core +2 more sources
BMC Research Notes, 2023 Objective Studies have shown that Flavivirus infection remodels the host cell to favour viral replication. In particular, the host cell lipid profile is altered, and it has been proposed that this process alters membrane fluidity to allow wrapping of the
Suwipa Ramphan +8 more
doaj +1 more source
Virus-like Particles: Measures and Biological Functions
Viruses, 2022 Virus-like particles resemble infectious virus particles in size, shape, and molecular composition; however, they fail to productively infect host cells.
Tara Bhat, Amy Cao, John Yin
doaj +1 more source