Results 21 to 30 of about 722,631 (394)
Epitope-Specific Anti-hCG Vaccines on a Virus Like Particle Platform. [PDF]
PLoS ONE, 2015 The possibility of a contraceptive vaccine targeting human chorionic gonadotropin has long been recognized, but never fully realized. Here we describe an epitope-specific approach based on immunogenic display of hCG-derived peptides on virus-like ...
Jerri Caldeira +4 more
doaj +1 more source
Development of a Virus-Like Particle-Based Anti-HER2 Breast Cancer Vaccine
Cancers, 2021 Simple Summary Virus-like particles (VLPs) have attracted significant interest as immunotherapy platforms and cancer vaccines for inducing antigen-specific immune responses against tumors.
He Hu, N. Steinmetz
semanticscholar +1 more source
Vaccines, 2023 New vaccine delivery technologies, such as mRNA, have played a critical role in the rapid and efficient control of SARS-CoV-2, helping to end the COVID-19 pandemic.
Yongping Yang +23 more
doaj +1 more source
Development of Respiratory Syncytial Virus Vaccine Candidates for the Elderly
Viruses, 2023 Respiratory syncytial virus (RSV) is a significant threat to elderly populations and repeated infections that occur throughout life are poorly protective. To assess the role of prior RSV infections as well as elderly immune senescence on vaccine efficacy,
Jorge C. G. Blanco +5 more
doaj +1 more source
Cross-Protection Induced by Virus-like Particles Derived from the Influenza B Virus
Biomedicines, 2022 The mismatch between the circulating influenza B virus (IBV) and the vaccine strain contributes to the rapid emergence of IBV infection cases throughout the globe, which necessitates the development of effective vaccines conferring broad protection. Here,
Hae-Ji Kang +5 more
doaj +1 more source
Journal of the American Medical Association (JAMA), 2020 Importance Chikungunya virus (CHIKV) is a mosquito-borne Alphavirus prevalent worldwide. There are currently no licensed vaccines or therapies. Objective To evaluate the safety and tolerability of an investigational CHIKV virus-like particle (VLP ...
Grace L. Chen +35 more
semanticscholar +1 more source
The 3Ds in virus‐like particle based‐vaccines: “Design, Delivery and Dynamics”
Immunological Reviews, 2020 Vaccines need to be rationally designed in order be delivered to the immune system for maximizing induction of dynamic immune responses. Virus‐like particles (VLPs) are ideal platforms for such 3D vaccines, as they allow the display of complex and native
Mona O. Mohsen, G. Augusto, M. Bachmann
semanticscholar +1 more source
On the micro PIV accuracy and reliability utilizing suspension particles of large, non-Gaussian particle image [PDF]
Exp Fluids 62, 191 (2021), 2020 Optical investigations on the dynamics of dense suspensions are challenging due to reduced optical accessibility. Furthermore, the suspension particle image size can strongly deviate from the optimal particle image size for PIV measurements. Optical accessibility can be achieved by refractive index matching of surface labelled suspension particles ...
arxiv +1 more source
Antibody Opsonization of a TLR9 Agonist–Containing Virus-like Particle Enhances In Situ Immunization
Journal of Immunology, 2020 Key Points Immunostimulation by CMP-001 requires anti-Qβ Ab. In mice, IT CMP-001 induces lymphoma regression that is enhanced by anti–PD-1. The immunologic and therapeutic effects of intratumoral (IT) delivery of a novel virus-like particle as a lymphoma
Caitlin D. Lemke-Miltner +6 more
semanticscholar +1 more source
Genetic Engineering Technique in Virus-Like Particle Vaccine Construction [PDF]
, 2021 Vaccine becomes a very effective strategy to deal with various infectious diseases even to the point of eradication as in the smalpox virus. At present many conventional vaccines such as inactivated and live-attenuated vaccines.
Rizqoh, Debie
core +1 more source