Results 171 to 180 of about 243,139 (310)

Human cytomegalovirus deploys molecular mimicry to recruit VPS4A to sites of virus assembly. [PDF]

PLoS Pathog
Butt BG, Fischer D, Rep AR, Schauflinger M, Read C, Böck T, Hirner M, Wienen F, Graham SC, von Einem J.   +9 more
europepmc   +2 more sources

From disorder to icosahedral symmetry: How conformation-switching subunits enable RNA virus assembly. [PDF]

Sci Adv
Li S, Tresset G, Zandi R.
europepmc   +1 more source

Machine-learning a virus assembly fitness landscape. [PDF]

PLoS One, 2021
Dechant PP, He YH.
europepmc   +1 more source

Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant

, 2023
Yaning Li, Yaping Shen, Ziwei Hu, Renhong Yan   +3 more
openalex   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Nipah virus matrix protein uses cortical actin to stabilize the virus assembly sites and promote budding. [PDF]

Sci Adv
Wang J, Kliemke V, Zhang M, Liu J, Matta GL, Wang Q, Luo Y, Liu G, Liu Q.   +8 more
europepmc   +1 more source

Structures of a large prolate virus capsid in unexpanded and expanded states generate insights into the icosahedral virus assembly. [PDF]

Proc Natl Acad Sci U S A, 2022
Fang Q, Tang WC, Fokine A, Mahalingam M, Shao Q, Rossmann MG, Rao VB.   +6 more
europepmc   +1 more source

Cytoplasmic Motifs in the Nipah Virus Fusion Protein Modulate Virus Particle Assembly and Egress [PDF]

, 2017
Gunner P. Johnston, Erik Contreras, Jeffrey Dabundo, Bryce A. Henderson, Keesha M. Matz, Victoria Ortega, Alfredo Ramı́rez, Arnold Park, Hector C. Aguilar   +8 more
openalex   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Rational design of self-assembled RNA nanostructures for HIV-1 virus assembly blockade. [PDF]

Nucleic Acids Res, 2022
Qu N, Ying Y, Qin J, Chen AK.
europepmc   +1 more source