Results 11 to 20 of about 204,789 (305)
The phylogenomics of evolving virus virulence. [PDF]
Nat Rev Genet, 2018 How virulence evolves after a virus jumps to a new host species is central to disease emergence. Our current understanding of virulence evolution is based on insights drawn from two perspectives that have developed largely independently: long-standing evolutionary theory based on limited real data examples that often lack a genomic basis, and ...
Geoghegan JL, Holmes EC.
europepmc +4 more sources
Pathogenicity and virulence of hepatitis A virus [PDF]
Virulence, 2021 Hepatitis A is an acute infection of the liver, which is mostly asymptomatic in children and increases the severity with age. Although in most patients the infection resolves completely, in a few of them it may follow a prolonged or relapsed course or even a fulminant form.
Pintó, Rosa +6 more
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Viruses, 2022 African swine fever virus (ASFV) produces a lethal disease (ASF) in domestic pigs, which is currently causing a pandemic deteriorating pig production across Eurasia.
Elizabeth Ramirez-Medina +10 more
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African Swine Fever Virus Interaction with Host Innate Immune Factors
Viruses, 2023 African swine fever virus (ASFV) adversely affects pig farming owing to its 100% mortality rate. The condition is marked by elevated body temperature, bleeding, and ataxia in domestic pigs, whereas warthogs and ticks remain asymptomatic despite being ...
Ayoola Ebenezer Afe +4 more
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Pathogenesis and virulence of herpes simplex virus [PDF]
Virulence, 2021 Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital herpes, herpes stromal keratitis, meningitis and encephalitis. The intrinsic, innate and adaptive immune responses are key to control HSV, and the virus has developed ...
Shuyong Zhu, Abel Viejo-Borbolla
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Viruses, 2023 The classical swine fever virus (CSFV) particle consists of three glycoproteins, all of which have been shown to be important proteins involved in many virus functions, including interaction with several host proteins. One of these proteins, E2, has been
Elizabeth Vuono +7 more
doaj +1 more source
Pathogenicity and virulence of Hepatitis B virus [PDF]
Virulence, 2022 Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are an estimated 296 million people in the world that are chronically infected by this virus, and many of them will develop severe liver diseases including hepatitis, cirrhosis and hepatocellular carcinoma (HCC).
Yu-Chen Chuang +2 more
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Pathogenicity and virulence of Marburg virus
Virulence, 2022 Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever, causing organ dysfunction and death. Exposure to fruit bats in caves and mines, and human-to-human transmission had major roles in the amplification of MARV outbreaks in African ...
Mehedy Hasan Abir +13 more
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The Infectious Disease Ontology in the Age of COVID-19 [PDF]
, 2021 The Infectious Disease Ontology (IDO) is a suite of interoperable ontology modules that aims to provide coverage of all aspects of the infectious disease domain, including biomedical research, clinical care, and public health.
Babcock, Shane +3 more
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Defective interfering virus particles modulate virulence [PDF]
Journal of Virology, 1985 To determine whether defective interfering (DI) particles modulate virulence by initiating a cyclic pattern of virus growth in vivo, adult mice were infected with vesicular stomatitis virus (VSV), both with and without DI particles. A total of 184 mice divided into groups were inoculated intranasally.
D R, Cave, F M, Hendrickson, A S, Huang
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