Deletion of the H240R Gene in African Swine Fever Virus Partially Reduces Virus Virulence in Swine [PDF]
Viruses, 2023 African swine fever (ASF) is a highly contagious disease that affects wild and domestic swine. Currently, the disease is present as a pandemic affecting pork production in Eurasia and the Caribbean region.
Elizabeth Ramirez-Medina +7 more
doaj +2 more sources
The phylogenomics of evolving virus virulence. [PDF]
Nat Rev Genet, 2018 How virulence evolves after a virus jumps to a new host species is central to disease emergence. Our current understanding of virulence evolution is based on insights drawn from two perspectives that have developed largely independently: long-standing evolutionary theory based on limited real data examples that often lack a genomic basis, and ...
Geoghegan JL, Holmes EC.
europepmc +6 more sources
Arabidopsis thaliana Genes Associated with Cucumber mosaic virus Virulence and Their Link to Virus Seed Transmission [PDF]
Microorganisms, 2021 Virulence, the effect of pathogen infection on progeny production, is a major determinant of host and pathogen fitness as it affects host fecundity and pathogen transmission.
Nuria Montes +4 more
doaj +2 more sources
Pathogenesis and virulence of herpes simplex virus [PDF]
Virulence, 2021 Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital herpes, herpes stromal keratitis, meningitis and encephalitis. The intrinsic, innate and adaptive immune responses are key to control HSV, and the virus has developed ...
Shuyong Zhu, Abel Viejo-Borbolla
openaire +5 more sources
Pathogenicity and virulence of Marburg virus
Virulence, 2022 Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever, causing organ dysfunction and death. Exposure to fruit bats in caves and mines, and human-to-human transmission had major roles in the amplification of MARV outbreaks in African ...
Mehedy Hasan Abir +13 more
openaire +5 more sources
Marek's Disease Virus Virulence Genes Encode Circular RNAs. [PDF]
J Virol, 2022 Chasseur AS +9 more
europepmc +2 more sources
Altered virulence of Highly Pathogenic Avian Influenza (HPAI) H5N8 reassortant viruses in mammalian models [PDF]
Virulence, 2018 Recently identified highly pathogenic avian influenza (HPAI) H5N8 viruses (clade 2.3.4.4) are relatively low to moderately pathogenic in mammalian hosts compared with HPAI H5N1 viruses.
Su-Jin Park +11 more
doaj +2 more sources
Virulence evolution of a salmonid virus following a host jump. [PDF]
PLoS PathogensEmergent viral diseases remain a critical obstacle to welfare across landscapes and species, encompassing humans, wildlife, and agriculture. Following a jump to a novel host, the severity of disease resulting from infection is a critical determinant of ...
Malina M Loeher +6 more
doaj +2 more sources
Enhanced virulence of mpox virus clade Ib over clade IIb in the CAST/EiJ mouse model. [PDF]
Commun BiolUnanue AR +8 more
europepmc +2 more sources
Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host [PDF]
, 2013 Schmallenberg virus (SBV) is an emerging orthobunyavirus of ruminants associated with outbreaks of congenital malformations in aborted and stillborn animals.
A Bridgen +73 more
core +21 more sources