Results 11 to 20 of about 33,802 (280)

Structure, gating and interactions of the voltage-dependent anion channel [PDF]

European Biophysics Journal, 2021
The voltage-dependent anion channel (VDAC) is one of the most highly abundant proteins found in the outer mitochondrial membrane, and was one of the earliest discovered. Here we review progress in understanding VDAC function with a focus on its structure,
Eszter E Najbauer, Stefan Becker, Karin Giller   +2 more
exaly   +11 more sources

Structure of the human voltage-dependent anion channel. [PDF]

Proceedings of the National Academy of Sciences, 2008
The voltage-dependent anion channel (VDAC), also known as mitochondrial porin, is the most abundant protein in the mitochondrial outer membrane (MOM).
Vonrhein, C., Giller, K., Habeck, M. ; https://orcid.org/, Zeth, K., Villinger, S., Bayrhuber, M., Becker , S., Becker, Stefan, Zweckstetter, Markus, Villinger , S., Giller, Karin, Zweckstetter, M., Villinger, Saskia, Becker, S., Bayrhuber, Monika, Habeck, Michael, Meins, Thomas, Griesinger, C., Vonrhein, Clemens, Zeth, Kornelius, Meins, T., Griesinger, Christian, Habeck, M.   +22 more
core   +9 more sources

VDAC1 (voltage-dependent anion channel 1) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012
Review on VDAC1 (voltage-dependent anion channel 1), with data on DNA, on the protein encoded, and where the gene is ...
Shoshan-Barmatz, V, Mizrachi, D
core   +3 more sources

Functional dynamics in the voltage-dependent anion channel [PDF]

Proceedings of the National Academy of Sciences, 2010
The voltage-dependent anion channel (VDAC), located in the outer mitochondrial membrane, acts as a gatekeeper for the entry and exit of mitochondrial metabolites.
Villinger, S., Zachariae, U., Zweckstetter, Markus, Zachariä, U., Adam Lange, Markus Zweckstetter, Villinger, Saskia, Zachariae, Ulrich; id_orcid, Becker, S., Zachariae, Ulrich, Briones, R., Saskia Villinger, Griesinger, Christian, Bert L. de Groot, Giller, K., Groot, Bert L. de, Rodolfo Briones, Stefan Becker, De Groot, B.L., de Groot, B., Karin Giller, Lange, A., Becker, Stefan, Giller, Karin, Zweckstetter, M., Griesinger, C., Christian Griesinger, Griesinger, C. ; https://orcid.org/, Ulrich Zachariae, de Groot, B. L., Lange, Adam, Briones, Rodolfo   +31 more
core   +7 more sources

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels. [PDF]

PLoS ONE, 2008
Type II hexokinase is overexpressed in most neoplastic cells, and it mainly localizes on the outer mitochondrial membrane. Hexokinase II dissociation from mitochondria triggers apoptosis.
Federica Chiara, Diego Castellaro, Oriano Marin, Valeria Petronilli, William S Brusilow, Magdalena Juhaszova, Steven J Sollott, Michael Forte, Paolo Bernardi, Andrea Rasola   +9 more
doaj   +3 more sources

A role for voltage-dependent anion channel Vdac1 in polyglutamine-mediated neuronal cell death. [PDF]

PLoS ONE, 2007
Expansion of trinucleotide repeats in coding and non-coding regions of genes is associated with sixteen neurodegenerative disorders. However, the molecular effects that lead to neurodegeneration have remained elusive.
Tanay Ghosh, Neeraj Pandey, Arindam Maitra, Samir K Brahmachari, Beena Pillai   +4 more
doaj   +3 more sources

Voltage-Dependent Anion Channel 1(VDAC1) Participates the Apoptosis of the Mitochondrial Dysfunction in Desminopathy. [PDF]

PLoS ONE, 2016
Desminopathies caused by the mutation in the gene coding for desmin are genetically protein aggregation myopathies. Mitochondrial dysfunction is one of pathological changes in the desminopathies at the earliest stage.
Huanyin Li, Lan Zheng, Yanqing Mo, Qi Gong, Aihua Jiang, Jing Zhao   +5 more
doaj   +2 more sources

Identification and validation of voltage‐dependent anion channel 1‐related genes and immune cell infiltration in diabetic nephropathy [PDF]

Journal of Diabetes Investigation
Aims/Introduction This study investigated the roles of voltage‐dependent anion channel 1‐related differentially expressed genes (VRDEGs) in diabetic nephropathy (DN).
Jiaqun Lin, Mengjie Weng, Jing Zheng, Kun Nie, Siyi Rao, Yongjie Zhuo, Jianxin Wan   +6 more
doaj   +2 more sources

The Single Residue K12 Governs the Exceptional Voltage Sensitivity of Mitochondrial Voltage-Dependent Anion Channel Gating. [PDF]

J Am Chem Soc, 2022
International audienceThe voltage-dependent anion channel (VDAC) is a βbarrel channel of the mitochondrial outer membrane (MOM) that passively transports ions, metabolites, polypeptides, and single-stranded DNA. VDAC responds to a transmembrane potential
Ngo VA, Queralt-Martín M, Khan F, Bergdoll L, Abramson J, Bezrukov SM, Rostovtseva TK, Hoogerheide DP, Noskov SY.   +8 more
europepmc   +6 more sources

A Chemical Glycoproteomics Platform Reveals O-GlcNAcylation of Mitochondrial Voltage-Dependent Anion Channel 2

Cell Reports, 2013
Protein modification by O-linked β-N-acetylglucosamine (O-GlcNAc) is a critical cell signaling modality, but identifying signal-specific O-GlcNAcylation events remains a significant experimental challenge.
Krishnan K. Palaniappan, Matthew J. Hangauer, Timothy J. Smith, Brian P. Smart, Austin A. Pitcher, Emily H. Cheng, Carolyn R. Bertozzi, Michael Boyce   +7 more
doaj   +2 more sources