A role for voltage-dependent anion channel Vdac1 in polyglutamine-mediated neuronal cell death. [PDF]
PLoS ONE, 2007 Expansion of trinucleotide repeats in coding and non-coding regions of genes is associated with sixteen neurodegenerative disorders. However, the molecular effects that lead to neurodegeneration have remained elusive.
Tanay Ghosh +4 more
doaj +1 more source
Porin 1 Modulates Autophagy in Yeast
Cells, 2021 Autophagy is a cellular recycling program which efficiently reduces the cellular burden of ageing. Autophagy is characterised by nucleation of isolation membranes, which grow in size and further expand to form autophagosomes, engulfing cellular material ...
Filomena Broeskamp +9 more
doaj +1 more source
Single-channel analysis of the anion channel-forming protein from the plant pathogenic bacterium Clavibacter michiganense ssp. nebraskense [PDF]
, 1993 Schürholz T, Dloczik L, Neumann E. Single-channel analysis of the anion channel-forming protein from the plant pathogenic bacterium Clavibacter michiganense ssp. nebraskense. Biophysical Journal.
Schürholz, Theo +2 more
core +1 more source
Can the Thermodynamic Hodgkin-Huxley Model of Voltage-Dependent Conductance Extrapolate for Temperature? [PDF]
, 2014 Hodgkin and Huxley (H-H) fitted their model of voltage-dependent conductances to experimental data using empirical functions of voltage. The thermodynamic H-H model of voltage dependent conductances is more physically plausible, as it constrains and ...
Michael D. Forrest +2 more
core +1 more source
VDAC: Voltage Dependant Anion Channel
The FASEB Journal, 2011 VDAC (Voltage Dependent Anion Channel) is a channel protein located on the outer mitochondrial membrane. It regulates mitochondria functions and cell respiration through the exchange of molecules between the cytoplasm and the organelle, such as ADP, ATP, anions, cations, and other small, hydrophilic molecules.
Patrick Jordan +18 more
openaire +1 more source
Protocol: optimised electrophyiological analysis of intact guard cells from arabidopsis [PDF]
, 2012 Genetic resources available for Arabidopsis thaliana make this species particularly attractive as a model for molecular genetic studies of guard cell homeostasis, transport and signalling, but this facility is not matched by accessible tools for ...
Adrian Hills +19 more
core +1 more source
β-Barrel Mobility Underlies Closure of the Voltage-Dependent Anion Channel [PDF]
Structure, 2012 The voltage-dependent anion channel (VDAC) is the major protein in the outer mitochondrial membrane, where it mediates transport of ATP and ADP. Changes in its permeability, induced by voltage or apoptosis-related proteins, have been implicated in apoptotic pathways.
Zachariae, Ulrich +12 more
openaire +5 more sources
Recombinant yeast VDAC2: a comparison of electrophysiological features with the native form
FEBS Open Bio, 2019 Voltage‐dependent anion channel isoform 2 of the yeast Saccharomyces cerevisiae (yVDAC2) was believed for many years to be devoid of channel activity. Recently, we isolated yVDAC2 and showed that it exhibits channel‐forming activity in the planar lipid ...
Andrea Magrì +7 more
doaj +1 more source
Concentration dependent ion selectivity in VDAC: a molecular dynamics simulation study. [PDF]
PLoS ONE, 2011 The voltage-dependent anion channel (VDAC) forms the major pore in the outer mitochondrial membrane. Its high conducting open state features a moderate anion selectivity.
Eva-Maria Krammer +2 more
doaj +1 more source
Microglial K(+) channel expression in young adult and aged mice. [PDF]
, 2015 The K(+) channel expression pattern of microglia strongly depends on the cells' microenvironment and has been recognized as a sensitive marker of the cells' functional state. While numerous studies have been performed on microglia in vitro, our knowledge
Tom Schilling +3 more
core +1 more source