Recombinant yeast VDAC2: a comparison of electrophysiological features with the native form
FEBS Open Bio, 2019 Voltage‐dependent anion channel isoform 2 of the yeast Saccharomyces cerevisiae (yVDAC2) was believed for many years to be devoid of channel activity. Recently, we isolated yVDAC2 and showed that it exhibits channel‐forming activity in the planar lipid ...
Andrea Magrì +7 more
doaj +1 more source
Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1 [PDF]
, 2017 Voltage-dependent anion channel-1 (VDAC1) is a highly regulated β-barrel membrane protein that mediates transport of ions and metabolites between the mitochondria and cytosol of the cell.
Abramson, Jeff +10 more
core +3 more sources
Isolation of a novel human voltage-dependent anion channel gene [PDF]
European Journal of Human Genetics, 1998 The voltage-dependent anion channel of the mitochondrial outer membrane (VDAC) is a small, abundant pore-forming protein found in the outer membranes of all eukaryotic mitochondria. The VDAC protein is believed to control the movement of adenine nucleotides through the outer membrane and to be the mitochondrial binding site for hexokinase and glycerol ...
Z, Rahmani, C, Maunoury, A, Siddiqui
openaire +2 more sources
Amphiphilic blockers punch through a mutant CLC-0 pore. [PDF]
, 2009 Intracellularly applied amphiphilic molecules, such as p-chlorophenoxy acetate (CPA) and octanoate, block various pore-open mutants of CLC-0. The voltage-dependent block of a particular pore-open mutant, E166G, was found to be multiphasic. In symmetrical
Chen, Tsung-Yu, Zhang, Xiao-Dong
core +2 more sources
SWELL1 is a glucose sensor regulating β-cell excitability and systemic glycaemia
Nature Communications, 2018 Insulin secretion by β-cells is stimulated by glucose and is dependent on the induction of β-cell membrane depolarization, mainly driven by the closure of KATP channels, which in turn promotes voltage-gated Ca2+ channel opening. Here Kang et al.
Chen Kang +10 more
doaj +1 more source
Multiple neurosteroid and cholesterol binding sites in voltage-dependent anion channel-1 determined by photo-affinity labeling. [PDF]
Biochim Biophys Acta Mol Cell Biol Lipids, 2019 Cheng WWL +12 more
europepmc +2 more sources
Nanoscale-targeted patch-clamp recordings of functional presynaptic ion channels [PDF]
, 2013 Important modulatory roles have been attributed to presynaptic NMDA receptors (NMDARs) located on cerebellar interneuron terminals. Evidence supporting a presynaptic location includes an increase in the frequency of mini events following the application ...
Benton, DCH +4 more
core +1 more source
BAK regulates catalase release from peroxisomes
Molecular & Cellular Oncology, 2017 Loss of voltage-dependent anion channel 2 (VDAC2) leads to impaired peroxisome biogenesis in mammalian cells. Knockdown of BAK restores peroxisomal biogenesis in VDAC2-deficient cells, where BAK localization shifts from mitochondria to peroxisomes ...
Yukio Fujiki +4 more
doaj +1 more source
A personal historic perspective on the role of chloride in skeletal and cardiac muscle [PDF]
, 2017 During the early decades of the last century, skeletal muscle was held to be impermeable to chloride ions. This theory, based on shaky grounds, was famously falsified by Boyle and Conway in 1941.
Hutter, Otto F.
core +1 more source
Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]
, 2007 Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Aljamal J.A. +8 more
core +1 more source