Results 41 to 50 of about 4,682,761 (283)

The response of the tandem pore potassium channel TASK-3 (K2P9.1) to voltage : gating at the cytoplasmic mouth [PDF]

, 2009
Although the tandem pore potassium channel TASK-3 is thought to open and shut at its selectivity filter in response to changes of extracellular pH, it is currently unknown whether the channel also shows gating at its inner, cytoplasmic mouth through ...
Feng, J. F., Puja R. Mehta, Sutcliffe, M. J., M. J. Sutcliffe, Mehta, Puja R., Stanfield, P. R., Stanfield, Peter R., Stansfeld, P. J., Feng, J.F., Sutcliffe, M.J., Vavoulis, Dimitris V., Mehta, Puja, R., Vavoulis, D. V., Ashmole, I., Stansfeld, P.J., Feng, Jianfeng, Stansfeld, Phillip J., I. Ashmole, J. F. Feng, P. J. Stansfeld, Vavoulis, D.V., D. V. Vavoulis, P. R. Stanfield, Stanfield, P.R.   +23 more
core   +1 more source

Voltage-dependent anion channels in the plasma membrane of guard cells [PDF]

Nature, 1989
WHEN plants assimilate CO2 from the atmosphere, water vapour escapes. This exchange of gases can be moderated by the plant through volume changes of guard cells, which in pairs surround each stomatal pore in the epidermis and act as turgor-operated valves.
Keller, B., Hedrich, R., Raschke, K.
openaire   +2 more sources

SWELL1 is a glucose sensor regulating β-cell excitability and systemic glycaemia

Nature Communications, 2018
Insulin secretion by β-cells is stimulated by glucose and is dependent on the induction of β-cell membrane depolarization, mainly driven by the closure of KATP channels, which in turn promotes voltage-gated Ca2+ channel opening. Here Kang et al.
Chen Kang, Litao Xie, Susheel K. Gunasekar, Anil Mishra, Yanhui Zhang, Saachi Pai, Yiwen Gao, Ashutosh Kumar, Andrew W. Norris, Samuel B. Stephens, Rajan Sah   +10 more
doaj   +1 more source

Electrophysiological characterization of activation state-dependent Cav2 channel antagonist TROX-1 in spinal nerve injured rats. [PDF]

, 2015
Prialt, a synthetic version of Cav2.2 antagonist ω-conotoxin MVIIA derived from Conus magus, is the first clinically approved voltage-gated calcium channel blocker for refractory chronic pain.
Schiene, K., Damann, N., Damann, N, Rutten, K., Wigge, S., Schiene, K, Christoph, T., Schunk, S., Valdor, M, Valdor, M., Rutten, K, Schunk, S, Patel, R, Dickenson, A.H., Christoph, T, Wigge, S, Patel, R., Dickenson, AH   +17 more
core   +1 more source

Involvement of voltage-dependent anion channel (VDAC) in dengue infection [PDF]

Scientific Reports, 2016
AbstractDuring infection, dengue virus (DENV) proteins interact with host cellular constituents promoting the remodeling of the cell to facilitate virus production. While a number of interacting proteins have been identified for DENV non-structural proteins, far fewer interacting partners have been identified for the DENV structural proteins.
Kunlakanya Jitobaom, Natthida Tongluan, Duncan R. Smith   +2 more
openaire   +2 more sources

BAK regulates catalase release from peroxisomes

Molecular & Cellular Oncology, 2017
Loss of voltage-dependent anion channel 2 (VDAC2) leads to impaired peroxisome biogenesis in mammalian cells. Knockdown of BAK restores peroxisomal biogenesis in VDAC2-deficient cells, where BAK localization shifts from mitochondria to peroxisomes ...
Yukio Fujiki, Non Miyata, Satoru Mukai, Kanji Okumoto, Emily H. Cheng   +4 more
doaj   +1 more source

Research progress in targeting voltage-dependent anion channel-1 for cancer therapy [PDF]

Jichu yixue yu linchuang
Voltage-dependent anion channel-1 (VDAC1), a key regulator of mitochondrial function, is highly expressed in various cancers and is associated with poor prognosis.
XU Jiaai, GUO Ying, ZHANG Chao, LI He, YANG Chunhua
doaj   +1 more source

Isolation of a novel human voltage-dependent anion channel gene [PDF]

European Journal of Human Genetics, 1998
The voltage-dependent anion channel of the mitochondrial outer membrane (VDAC) is a small, abundant pore-forming protein found in the outer membranes of all eukaryotic mitochondria. The VDAC protein is believed to control the movement of adenine nucleotides through the outer membrane and to be the mitochondrial binding site for hexokinase and glycerol ...
Z, Rahmani, C, Maunoury, A, Siddiqui
openaire   +2 more sources

A voltage-dependent chloride channel fine-tunes photosynthesis in plants

Nature Communications, 2016
Plants have evolved to maximize energy capture while protecting their photosynthetic machinery in response to rapid variation in light conditions.
Andrei Herdean, Enrico Teardo, Anders K. Nilsson, Bernard E. Pfeil, Oskar N. Johansson, Renáta Ünnep, Gergely Nagy, Ottó Zsiros, Somnath Dana, Katalin Solymosi, Győző Garab, Ildikó Szabó, Cornelia Spetea, Björn Lundin   +13 more
doaj   +1 more source

Molecular mechanisms of the coupling of gating to voltage sensing in transmembrane proteins [PDF]

, 2014
Voltage gated potassium ion (Kv) channels regulate action potentials of the nervous system by responding to changes in transmembrane voltage, enabling K+ transport across the membrane to restore cells to their resting potential.
Starek, Greg
core   +1 more source