Results 11 to 20 of about 194,442 (307)

Proteolytic maturation of α 2 δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels [PDF]

eLife, 2016
The auxiliary α2δ subunits of voltage-gated calcium channels are extracellular membrane-associated proteins, which are post-translationally cleaved into disulfide-linked polypeptides α2 and δ.
Alexopoulos, O, Bauer, CS, Dolphin, AC, Douglas, LR, Ferron, L, Kadurin, I, Lana, B, Margas, W, Meyer, JO, Nieto-Rostro, M, Pratt, WS, Rothwell, SW   +11 more
core   +5 more sources

Voltage-dependent calcium channel signaling mediates GABAA receptor-induced migratory activation of dendritic cells infected by Toxoplasma gondii. [PDF]

PLoS Pathog, 2017
Kanatani S, Fuks JM, Olafsson EB, Westermark L, Chambers B, Varas-Godoy M, Uhlén P, Barragan A.   +7 more
europepmc   +3 more sources

A novel binding site between the voltage-dependent calcium channel Ca_V1.2 subunit and Ca_Vβ2 subunit discovered using a new analysis method for protein-protein interactions. [PDF]

Sci Rep, 2023
We developed a new method to analyze protein–protein interactions using a dual-inducible prokaryotic expression system. To evaluate protein–protein binding, a chimeric fusion toxin gene was constructed using a DNase-treated short DNA fragment (epitope ...
Murakami AM, Nagatomo K, Miyoshi I, Itagaki S, Niwa Y, Murakami M.   +5 more
europepmc   +2 more sources

Renzhu Ointment Regulates L-Type Voltage-Dependent Calcium Channel in Mice Model of Senna-Induced Diarrhea by Transdermal Administration. [PDF]

Drug Des Devel Ther, 2023
Lian Zhong,1,* Xiaoyu Cao,2,* Li Li,1 Yuanyuan He,1 Yanxia Liu,1 Weiwei Chen,1 Fuzhen Yang,1 Ni Xiao,1 Jun Zhang,1 Huifen He3 1School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, People’s Republic of ...
Zhong L, Cao X, Li L, He Y, Liu Y, Chen W, Yang F, Xiao N, Zhang J, He H.   +9 more
europepmc   +2 more sources

Bio-inspired voltage-dependent calcium channel blockers. [PDF]

Nat Commun, 2013
Yang T, He LL, Chen M, Fang K, Colecraft HM.   +4 more
europepmc   +3 more sources

Shear-induced ciliary autotomy mediated by a TRP channel and a voltage-dependent calcium channel. [PDF]

iScience
Summary: Cilium, an organelle for sensory transduction and cell motility, dynamically grows and disappears depending on stimulus perception and cell-cycle progression.
Hui S, Kimura M, Kadowaki Y, Tsuji M, Inoue M, Watanabe N, Yoshimura K.   +6 more
europepmc   +2 more sources

Voltage-dependent calcium channel α2δ1 subunit is a specific candidate marker for identifying gastric cancer stem cells. [PDF]

Cancer Manag Res, 2019
Zhang Z, Zhao W, Lin X, Gao J, Zhang Z, Shen L.   +5 more
europepmc   +3 more sources

Acidic amino acids in the first intracellular loop contribute to voltage- and calcium- dependent gating of anoctamin1/TMEM16A. [PDF]

PLoS ONE, 2014
Anoctamin1 (Ano1, or TMEM16A) is a Ca2+-activated chloride channel that is gated by both voltage and Ca2+. We have previously identified that the first intracellular loop that contains a high density of acidic residues mediates voltage- and calcium ...
Qinghuan Xiao, Yuanyuan Cui
doaj   +1 more source

Forskolin Regulates L-Type Calcium Channel through Interaction between Actinin 4 and β3 Subunit in Osteoblasts. [PDF]

PLoS ONE, 2015
Voltage-dependent L-type calcium channels that permit cellular calcium influx are essential in calcium-mediated modulation of cellular signaling. Although the regulation of voltage-dependent L-type calcium channels is linked to many factors including ...
Xuemei Zhang, Fangping Li, Lin Guo, Hongya Hei, Lulu Tian, Wen Peng, Hui Cai   +6 more
doaj   +1 more source

Cholesterol influences voltage-gated calcium channels and BK-type potassium channels in auditory hair cells. [PDF]

PLoS ONE, 2011
The influence of membrane cholesterol content on a variety of ion channel conductances in numerous cell models has been shown, but studies exploring its role in auditory hair cell physiology are scarce.
Erin K Purcell, Liqian Liu, Paul V Thomas, R Keith Duncan   +3 more
doaj   +1 more source