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Diseases caused by voltage-gated ion channels
Molecular Aspects of Medicine, 1997Ion channels regulate the transfer of ions between the outer and the inner surface of the cell membrane. The opening of ion channels may be triggered by the binding of a ligand or variations in the membrane potential. Voltage-gated ion channels are an important class of such channels, that are involved in the generation and propagation of action ...
B, Fontaine +2 more
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Structure and Function of Voltage-Gated Ion Channels
Naturwissenschaften, 1998Voltage-gated ion channels are key molecules for the generation of electrical signals in cells. They are integral membrane proteins which are activated by a depolarized membrane potential resulting in a conformational change, allowing ions to permeate.
H, Terlau, W, Stühmer
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2011
Both voltage-gated and ligand-gated ion channels are large protein molecules, as is the sodium pump Na,K-ATPase. In recent years the primary structure of a number of them has been determined, and by combining this information with the biophysical evidence, major advances have been made in our understanding of how they work at the molecular and ...
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Both voltage-gated and ligand-gated ion channels are large protein molecules, as is the sodium pump Na,K-ATPase. In recent years the primary structure of a number of them has been determined, and by combining this information with the biophysical evidence, major advances have been made in our understanding of how they work at the molecular and ...
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International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels
Pharmacological Reviews, 2003W. Catterall +7 more
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Voltage-Gated Ion Channels in the PNS: Novel Therapies for Neuropathic Pain?
TIPS - Trends in Pharmacological Sciences, 2016G. Tibbs, D. J. Posson, P. A. Goldstein
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The distribution and targeting of neuronal voltage-gated ion channels
Nature Reviews Neuroscience, 2006H. Lai, L. Jan
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