Results 11 to 20 of about 1,936,199 (178)
VKCDB: Voltage-gated potassium channel database [PDF]
BMC Bioinformatics, 2004 Background The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based component of the membrane potential and are thus central to many critical ...
Gallin Warren J, Li Bin
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Direct neurotransmitter activation of voltage-gated potassium channels [PDF]
Nature Communications, 2018 M-current is conveyed by voltage-sensitive KCNQ channels, which are enriched in GABAergic neurons and are activated by anticonvulsants such as retigabine.
Rían W. Manville +2 more
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The structure of a voltage gated potassium channel [PDF]
, 2010 Voltage gated potassium channels (Kv channels) are tetrameric ion channels, responsible for regulating the potassium component of the membrane potential in a large range of cell types ranging from mammalian excitable cells to bacteria. Attempts have been made to elucidate the structure of voltage gated potassium channels using X-ray crystallography ...
Rogers, Nik
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Structural and functional modularity of voltage‐gated potassium channels [PDF]
FEBS Letters, 1999 Sequence similarity among known potassium channels indicates the voltage‐gated potassium channels consist of two modules: the N‐terminal portion of the channel up to and including transmembrane segment S4, called in this paper the ‘sensor’ module, and the C‐terminal portion from transmembrane segment S5 onwards, called the ‘pore’ module.
Patten C. D. +3 more
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Structure and function of potassium and calcium channels [PDF]
, 2005 In this thesis, potassium channels human Kv2.1 and rat Kv2.1, along with calcium channels Ca, 1.2, Ca, 3.1, and chimeras have been studied. These channels were expressed in Xenopuso ocytesf or electrophysiological experiments using two electrode voltage
Stevens, Louisa Rebecca
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Mechanisms of Activation of Voltage-Gated Potassium Channels [PDF]
Acta Naturae, 2014 Voltage-gated potassium ion channels (Kv) play an important role in a variety of cellular processes, including the functioning of excitable cells, regulation of apoptosis, cell growth and differentiation, the release of neurotransmitters and hormones, maintenance of cardiac activity, etc.
GRIZEL A.V., GLUKHOV G.S., SOKOLOVA O.S.
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Functional reconstitution of a voltage-gated potassium channel in giant unilamellar vesicles. [PDF]
PLoS ONE, 2011 Voltage-gated ion channels are key players in cellular excitability. Recent studies suggest that their behavior can depend strongly on the membrane lipid composition and physical state. In vivo studies of membrane/channel and channel/channel interactions
Sophie Aimon +5 more
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Role of Kv1 potassium channels in regulating dopamine release and presynaptic D2 receptor function. [PDF]
PLoS ONE, 2011 Dopamine (DA) release in the CNS is critical for motor control and motivated behaviors. Dysfunction of its regulation is thought to be implicated in drug abuse and in diseases such as schizophrenia and Parkinson's.
Philippe Martel +4 more
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Heliyon, 2023 Osteoarthritis (OA) is one of the leading causes of chronic pain and dysfunction. It is essential to comprehend the nature of pain and cartilage degeneration and its influencing factors on OA treatment. Voltage-gated ion channels (VGICs) are essential in
Xinwei Wang, Xueping Li
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Photocontrol of Voltage-Gated Ion Channel Activity by Azobenzene Trimethylammonium Bromide in Neonatal Rat Cardiomyocytes. [PDF]
PLoS ONE, 2016 The ability of azobenzene trimethylammonium bromide (azoTAB) to sensitize cardiac tissue excitability to light was recently reported. The dark, thermally relaxed trans- isomer of azoTAB suppressed spontaneous activity and excitation propagation speed ...
Sheyda R Frolova +4 more
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