Results 81 to 90 of about 2,241,154 (143)

Voltage gated sodium channels as therapeutic targets for chronic pain

Journal of Pain Research, 2019
Renee Siu Yu Ma,1 Kayani Kayani,1 Danniella Whyte-Oshodi,1 Aiyesha Whyte-Oshodi,2 Nitish Nachiappan,3 Shaene Gnanarajah,1 Raihan Mohammed1 1Department of Medicine, University of Cambridge, Cambridge, UK; 2Faculty of Medicine,
Ma RSY, Kayani K, Whyte-Oshodi D, Whyte-Oshodi A, Nachiappan N, Gnanarajah S, Mohammed R   +6 more
doaj  

Trifunctional Saxitoxin Conjugates for Covalent Labeling of Voltage-Gated Sodium Channels. [PDF]

Chembiochem, 2023
Finkelstein DS, Du Bois J.
europepmc   +1 more source

Structural characterization of δβγ epithelial sodium channels provide insight into channel assembly

When thinking of sodium channels in the nervous system the most notable are voltage gated sodium channels, but a multitude of non-voltage gated channels also contribute to sodium homeostasis in the brain.
Houser, Alexandra
core   +1 more source

Phenytoin Derivatives as Antagonists of AMPA Receptors and Voltage-Gated Sodium Channels: A Structure-Function Study. [PDF]

Int J Mol Sci
Zhigulin AS, Nikolaev MV, Dron MY, Vasilenko DA, Barygin OI, Tikhonov DB.   +5 more
europepmc   +1 more source

Nanoscale organization in the cell membrane dynamically modulates the biophysics of voltage-gated sodium channels. [PDF]

Nat Commun
Tarasov M, Ammon M, Wirth JO, Hampton C, Selimi Z, Veeraraghavan R, Radwański PB.   +6 more
europepmc   +1 more source

Development of specific modulators of voltage-gated sodium channels

This project will identify novel modulators of voltage-gated sodium (NaV) channels, a type of sodium-conducting integral membrane proteins, which play a central role in neuronal, muscular, and cardiac function.

core  

Evolution of voltage-gated sodium channels

, 2013
Voltage-gated sodium channels play important roles in the nervous system by enabling propagation of action potentials along axons. It has been suggested that sodium channels evolved from calcium channels before the split of animals and choanoflagellates,
Widmark, Jenny,, Larhammar, Dan,
core  

Effects of voltage-gated sodium channels on the median effective dose of ropivacaine in diabetic rats. [PDF]

Sci Rep
Song X, Lv K, Yu P, Liu X, Yu Y, Cao G, Tai Y, Zhao B, Wang Q.   +8 more
europepmc   +1 more source

Alternative splicing in voltage-gated sodium channels: mechanisms, regulatory networks and therapeutic implications. [PDF]

Ann Med
Qiu J, Wu P, Zhang Y, Li Y, Xia C, Peng S, Sun J.   +6 more
europepmc   +1 more source

Molecular Dynamics Simulations of Ion Permeation in Human Voltage-Gated Sodium Channels. [PDF]

J Chem Theory Comput, 2023
Alberini G, Alexis Paz S, Corradi B, Abrams CF, Benfenati F, Maragliano L.   +5 more
europepmc   +1 more source