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pH Modulation of Voltage-Gated Sodium Channels
2018Changes in blood and tissue pH accompany physiological and pathophysiological conditions including exercise, cardiac ischemia, ischemic stroke, and cocaine ingestion. These conditions are known to trigger the symptoms of electrical diseases in patients carrying sodium channel mutations.
Colin H, Peters +3 more
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Effects of Benzothiazolamines on Voltage-Gated Sodium Channels
2017Benzothiazole is a versatile fused heterocycle that aroused much interest in drug discovery as anticonvulsant, neuroprotective, analgesic, anti-inflammatory, antimicrobial, and anticancer. Two benzothiazolamines, riluzole and lubeluzole, are known blockers of voltage-gated sodium (Nav) channels.
Farinato, Alessandro +2 more
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Voltage gated sodium channels in cancer and their potential mechanisms of action
Channels, 2019Peter Ruben
exaly
Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels
Annual Review of Pharmacology and Toxicology, 2020William Catterall +2 more
exaly