Results 121 to 130 of about 62,302 (192)

Pharmacological targeting and characterization of Voltage-Gated Sodium Channels (VGSCs) expressed in the high-grade glioma microenvironment. [PDF]

BMC Cancer
Fletcher EV, Shard C, Boyle Y, Milligan CJ, Cross RSN, Jones AC, Francis A, Dewdney B, Barker M, Rezaeiravesh S, Ng ZY, Yeow Y, Kuznetsova I, Jones ME, Ormsby RJ, Poonnoose SI, Patil A, Valvi S, Jenkins MR, Forrest ARR, Petrou S, Gomez GA, Johns TG.   +22 more
europepmc   +1 more source

LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons.

Cell, 2023
Libé-Philippot B, Lejeune A, Wierda K, Louros N, Erkol E, Vlaeminck I, Beckers S, Gaspariunaite V, Bilheu A, Konstantoulea K, Nyitrai H, De Vleeschouwer M, Vennekens KM, Vidal N, Bird TW, Soto DC, Jaspers T, Dewilde M, Dennis MY, Rousseau F, Comoletti D, Schymkowitz J, Theys T, de Wit J, Vanderhaeghen P.   +24 more
europepmc   +1 more source

Voltage-Gated Sodium Channels: A Therapeutic Target in Ischemic Heart Disease. [PDF]

Rev Cardiovasc Med
Zhang XL, Wei TP, Yang F, Liu HH, Qian LL, Wang RX.   +5 more
europepmc   +1 more source

Non-psychotropic phytocannabinoid interactions with voltage-gated sodium channels: An update on cannabidiol and cannabigerol. [PDF]

Front Physiol, 2022
Ghovanloo MR, Dib-Hajj SD, Goodchild SJ, Ruben PC, Waxman SG.   +4 more
europepmc   +1 more source

Voltage-gated sodium channels in diabetic sensory neuropathy: Function, modulation, and therapeutic potential. [PDF]

Front Cell Neurosci, 2022
Bigsby S, Neapetung J, Campanucci VA.
europepmc   +1 more source

Electrophysiological Characterization of the Venom and Toxins from the Scorpion <i>Tityus championi</i> Targeting Voltage-Gated Sodium Channels and Molecular Modeling of Tch3, a Toxin with Therapeutic Potential for Pain Relief. [PDF]

Biomolecules
Akerman-Sánchez G, Peigneur S, Carleer K, Ortiz N, Navia F, Fierro L, Castaño S, Díaz C, Tytgat J, Brenes O.   +9 more
europepmc   +1 more source

Cardiac involvement in patient-specific induced pluripotent stem cells of myotonic dystrophy type 1: unveiling the impact of voltage-gated sodium channels. [PDF]

Front Physiol, 2023
Pierre M, Djemai M, Chapotte-Baldacci CA, Pouliot V, Puymirat J, Boutjdir M, Chahine M.   +6 more
europepmc   +1 more source

Review of Physiology, Pathology, and Pharmacology of Voltage-Gated Sodium Channels in Regards to the Potential Role of NaV 1.8 Selective Inhibitor, Suzetrigine, for Chronic Pain Management. [PDF]

J Pain Res
Lam CM, Robinson CL, Aiyer R, Mata R, Xie K, Slitzky M, Latif H, Braun EB, Schatman ME, Gilligan C, Soin A, Latif U.   +11 more
europepmc   +1 more source

Venom Peptides Across Asian and American Tarantulas Utilize Dual Pharmacology to Target Activation and Fast Inactivation of Voltage-Gated Sodium Channels. [PDF]

Toxins (Basel)
Nashikwala AS, Kotapati C, Eagles DA, Lewis RJ, Cardoso FC.   +4 more
europepmc   +1 more source

Voltage-gated sodium channels in excitable cells as drug targets. [PDF]

Nat Rev Drug Discov
Alsaloum M, Dib-Hajj SD, Page DA, Ruben PC, Krainer AR, Waxman SG.   +5 more
europepmc   +1 more source