Results 11 to 20 of about 45,419 (204)

A Subunit Vaccine Based on the VP2 Protein of Porcine Parvovirus 1 Induces a Strong Protective Effect in Pregnant Gilts [PDF]

Vaccines, 2023
Porcine parvovirus 1 (PPV1) is one of the most prevalent pathogens that can cause reproductive disorder in sows. The VP2 protein of PPV1 is the most important immunogenic protein that induces neutralizing antibodies and protective immunity.
Zhanye Ling, Huawei Zhang, Yingjin Chen, Leqiang Sun, Junlong Zhao   +4 more
doaj   +5 more sources

Identification of the NLS and NES motifs of VP2 from chicken anemia virus and the interaction of VP2 with mini-chromosome maintenance protein 3 [PDF]

BMC Veterinary Research, 2012
Background VP2 of chicken anemia virus (CAV) is a dual-specificity phosphatase required for virus infection, assembly and replication. The functions of the nuclear localization signal (NLS) and nuclear export signal (NES) of VP2 in the cell, however, are
Cheng Jai-Hong, Sheu Shyang-Chwen, Lien Yi-Yang, Lee Meng-Shiunn, Chen His-Jien, Su Wen-Hong, Lee Meng-Shiou   +6 more
doaj   +5 more sources

Construction and Evaluation of the Immunogenicity and Protective Efficacy of Recombinant Replication-Deficient Human Adenovirus-5 Expressing Genotype VII Newcastle Disease Virus F Protein and Infectious Bursal Disease Virus VP2 Protein [PDF]

Vaccines, 2023
Newcastle disease (ND) and infectious bursal disease (IBD) are two key infectious diseases that significantly threaten the health of the poultry industry.
Ting Xu, Ting Xiong, Wenting Xie, Jing Wu, Xiao Liu, Guimin Li, Yadi Lv, Linyu Li, Zekun Yang, Han Wang, Dingxiang Liu, Ruiai Chen   +11 more
doaj   +4 more sources

Identification of Host–Protein Interaction Network of Canine Parvovirus Capsid Protein VP2 in F81 Cells

Microorganisms
Canine Parvovirus (CPV) is a highly contagious virus that causes severe hemorrhagic enteritis and myocarditis, posing a major threat to the life and health of dogs. The molecular mechanism by which VP2, the major capsid protein of CPV, infects host cells
Hongzhuan Zhou, Huanhuan Zhang, Xia Su, Fuzhou Xu, Bing Xiao, Jin Zhang, Qi Qi, Lulu Lin, Kaidi Cui, Qinqin Li, Songping Li, Bing Yang   +11 more
doaj   +4 more sources

Rotavirus Nonstructural Protein NSP5 Interacts with Major Core Protein VP2 [PDF]

Journal of Virology, 2003
ABSTRACTRotavirus is a nonenveloped virus with a three-layered capsid. The inner layer, made of VP2, encloses the genomic RNA and two minor proteins, VP1 and VP3, with which it forms the viral core. Core assembly is coupled with RNA viral replication and takes place in definite cellular structures termed viroplasms.
Berois, Mabel, Sapin, Catherine, Erk, Inge, Poncet, Didier, Cohen, Jean   +4 more
openaire   +5 more sources

Study of the immunogenicity of the VP2 protein of canine parvovirus produced using an improved Baculovirus expression system [PDF]

BMC Veterinary Research, 2020
Background Canine parvovirus (CPV) is now recognized as a serious threat to the dog breeding industry worldwide. Currently used CPV vaccines all have their specific drawbacks, prompting a search for alternative safe and effective vaccination strategies ...
Dao Chang, Yangkun Liu, Yangyang Chen, Xiaomin Hu, Andrey Burov, Alexey Puzyr, Vladimir Bondar, Lunguang Yao   +7 more
doaj   +2 more sources

Interaction between the VP2 protein of deformed wing virus and host snapin protein and its effect on viral replication [PDF]

Frontiers in Microbiology, 2023
IntroductionDeformed wing virus (DWV) is one of the causative agents of colony collapse disorder. The structural protein of DWV plays a vital role in the process of viral invasion and host infection; however, there is limited research on DWV.Methods and ...
Li Sun, Ming Li, Yueyu Ma, Sichao Huang, Mingxiao Ma, Dongliang Fei   +5 more
doaj   +2 more sources

Identification and characterization of DNA aptamers specific to VP2 protein of canine parvovirus. [PDF]

Appl Microbiol Biotechnol, 2021
Canine parvovirus-2 (CPV-2) is ubiquitously distributed in dog population worldwide causing a severe and often fatal gastroenteritis. Owing to its highly contagious nature, rapid detection of CPV is crucial in effective control of the disease. Aptamers have emerged as potential alternative to antibodies as affinity reagents in diagnostic field. Present
Singh M, Tripathi P, Singh S, Sachan M, Chander V, Sharma GK, De UK, Kota S, Putty K, Singh RK, Nara S.   +10 more
europepmc   +4 more sources

Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry [PDF]

EMBO Journal, 1998
A complex of the polyomavirus internal protein VP2/VP3 with the pentameric major capsid protein VP1 has been prepared by co-expression in Escherichia coli. A C-terminal segment of VP2/VP3 is required for tight association, and a crystal structure of this segment, complexed with a VP1 pentamer, has been determined at 2.2 A resolution.
Xiaojiang S Chen, Thilo Stehle, Stephen C Harrison   +2 more
exaly   +3 more sources

Expression of recombinant 35 kDa fragment of VP2 protein of canine parvovirus using Escherichia coli expression system [PDF]

Veterinary World, 2021
Background and Aim: Canine parvovirus (CPV) is one of the most common viral infections in dogs, causing acute hemorrhagic gastroenteritis and high mortality. Vaccination effectively prevents CPV infection.
Natnaree Inthong, Sarawan Kaewmongkol, Nattakan Meekhanon, Eukote Suwan, Wanat Sricharern, Khomson Satchasataporn, Rungthiwa Sinsiri, Kaitkanoke Sirinarumitr, Theerapol Sirinarumitr   +8 more
doaj   +2 more sources