Results 51 to 60 of about 104,334 (371)

Finite VEVs from a Large Distance Vacuum Wave Functional [PDF]

, 1998
We show how to compute vacuum expectation values from derivative expansions of the vacuum wave functional. Such expansions appear to be valid only for slowly varying fields, but by exploiting analyticity in a complex scale parameter we can reconstruct ...
ALFONSO JARAMILLO, Basista B., Cornwall J., McAvity D. M., PAUL MANSFIELD, Symanzik K.   +5 more
core   +2 more sources

Preclinical Development of a vWF Aptamer to Limit Thrombosis and Engender Arterial Recanalization of Occluded Vessels.

Molecular Therapy, 2019
Endothelial surface and circulating glycoprotein von Willebrand factor (vWF) regulates platelet adhesion and is associated with thrombotic diseases, including ischemic stroke, myocardial infarction, and peripheral vascular disease.
S. M. Nimjee, D. Dornbos, G. Pitoc, D. Wheeler, J. Layzer, Nicholas M Venetos, Allyson L Huttinger, Spencer Talentino, N. Musgrave, Holly Moody, R. Rempel, Cheyenne Jones, Kendyl M Carlisle, Jenna Wilson, Camille Bratton, Matthew Joseph, Shoeb I. Khan, M. Hoffman, Laura J Sommerville, R. Becker, J. Zweier, B. Sullenger   +21 more
semanticscholar   +1 more source

Complex changes in von Willebrand factor-associated parameters are acquired during uncomplicated pregnancy. [PDF]

PLoS ONE, 2014
BACKGROUND:The coagulation protein von Willebrand Factor (VWF) is known to be elevated in pregnancy. However, the timing and nature of changes in VWF and associated parameters throughout pregnancy are not well understood.
Danielle N Drury-Stewart, Kerry W Lannert, Dominic W Chung, Gayle T Teramura, James C Zimring, Barbara A Konkle, Hilary S Gammill, Jill M Johnsen   +7 more
doaj   +1 more source

Comparative analysis of TRPM8 gene and COPD markers expression in rat lungs following exposure to cigarette smoke and tobacco aerosol

Acta Biomedica Scientifica
Background. Chronic Obstructive Pulmonary Disease (COPD) remains a global medical and social problem. The ion channel TRPM8, a cold receptor, is known to be involved in the pathogenesis of the disease.
P. D. Timkin, M. A. Kiselev, D. A. Shapovalova, D. E. Naumov, P. M. Linskaya, E. A. Borodin   +5 more
doaj   +1 more source

Evaluation of coagulation activation after Rhinovirus infection in patients with asthma and healthy control subjects: an observational study [PDF]

, 2014
Background Asthma exacerbations are frequently triggered by rhinovirus infections. Both asthma and respiratory tract infection can activate haemostasis. Therefore we hypothesized that experimental rhinovirus-16 infection and asthmatic airway inflammation
Bel, EHD, De Pol, MAV, Johnston, SL, Kamphuisen, PW, Lutter, R, Majoor, CJ, Meijers, JCM, Molenkamp, R, Nieuwland, R, Sterk, PJ, Van der Poll, T, Van der Sluijs, KF, Wolthers, KC   +12 more
core   +4 more sources

Enhanced VWF biosynthesis and elevated plasma VWF due to a natural variant in the murine Vwf gene

Blood, 2006
Abstract Both genetic and environmental influences contribute to the wide variation in plasma von Willebrand factor (VWF) levels observed in humans. Inbred mouse strains also have highly variable plasma VWF levels, providing a convenient model in which to study genetic modifiers of VWF.
Heidi L, Lemmerhirt, Jordan A, Shavit, Gallia G, Levy, Suzanne M, Cole, Jeffrey C, Long, David, Ginsburg   +5 more
openaire   +3 more sources

Two novel monoclonal antibodies to VWFA3 inhibit VWF‐collagen and VWF‐platelet interactions [PDF]

Journal of Thrombosis and Haemostasis, 2007
The interaction of collagen-von Willebrand factor (VWF)-GPIb is essential for platelet adhesion, especially under high shear conditions. VWF, which acts as a bridge between platelets and exposed subendothelium, interacts with collagen through its A3 domain, which is a new target for the antithrombotic agent.To develop functional blockers that ...
Y, Zhao, N, Dong, F, Shen, L, Xie, Y, He, F, Liu, C, Ruan   +6 more
openaire   +2 more sources

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice

TH Open, 2017
Background Inflammatory bowel disease (IBD) affects 1.6 million people in the United States. IBD is associated with an increased risk of thrombosis, which rises with disease activity.
Naamah L. Zitomersky, Melanie Demers, Kimberly Martinod, Maureen Gallant, Stephen M. Cifuni, Amlan Biswas, Scott Snapper, Denisa D. Wagner   +7 more
doaj   +1 more source

A conformation-sensitive monoclonal antibody against the A2 domain of von Willebrand factor reduces its proteolysis by ADAMTS13. [PDF]

PLoS ONE, 2011
The size of von Willebrand factor (VWF), controlled by ADAMTS13-dependent proteolysis, is associated with its hemostatic activity. Many factors regulate ADAMTS13-dependent VWF proteolysis through their interaction with VWF.
Jingyu Zhang, Zhenni Ma, Ningzheng Dong, Fang Liu, Jian Su, Yiming Zhao, Fei Shen, Anyou Wang, Changgeng Ruan   +8 more
doaj   +1 more source

Uterine spiral artery remodeling involves endothelial apoptosis induced by extravillous trophoblasts through Fas/FasL interactions. [PDF]

, 2005
Objective— Invasion of uterine spiral arteries by extravillous trophoblasts in the first trimester of pregnancy results in loss of endothelial and musculoelastic layers.
Ashton, SV, Baker, PN, Cartwright, JE, Crocker, IP, Dash, PR, Wareing, M, Whitley, GS   +6 more
core   +1 more source