Results 11 to 20 of about 24,286 (193)

Application of 3D scanning technology in Royal Malaysian Air Force Industrial Revolution 4.0‐based aircraft maintenance

open access: yesIET Networks, EarlyView., 2022
Abstract 3D scanning is rapidly becoming a key maintenance tool. Aerospace was a pioneer in adopting 3D scanning technology because aircraft manufacture and maintenance require precision. Monitoring deterioration, removing components for maintenance, and verifying covert operations are not practical or helpful without technology.
T. Nanthakumaran Thulasy   +4 more
wiley   +1 more source

Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus

open access: yes, 2008
Background The inhibitor telaprevir (VX-950) of the hepatitis C virus (HCV) protease NS3-4A has been tested in a recent phase 1b clinical trial in patients infected with HCV genotype 1. This trial revealed residue mutations that confer varying degrees of
Stefan Zeuzem   +32 more
core   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

Corr-4a diminishes negative effects of VX-770 on VX-809-rescued I507-ATT ΔF508 CFTR.

open access: yes, 2016
A. Mechanism of action of CFTR modulators used in our studies. B. Western blot analysis of I507-ATT and I507-ATC ΔF508 CFTR expressing HEK-293 cell lysates following vehicle control (0.15% DMSO, 16 h, 37°C) or corrector treatment (5μM VX-809, 5μM VX-770 ...
Purushotham Guroji (2805343)   +4 more
core   +1 more source

Interlayer‐Sliding‐Enabled Multiferroicity and Giant Switchable Anomalous Hall Conductivity in RuO2Zn2F2 Bilayer

open access: yesAdvanced Science, EarlyView.
Interlayer sliding in the RuO2Zn2F2 bilayer induces ferroelectricity and enables reversible valley polarization switching. The electric dipole and valley‐resolved band edges are intimately coupled, revealing sliding ferroelectricity as a powerful mechanism for electrical control of valley degrees of freedom in 2D materials.
Djamel Bezzerga   +3 more
wiley   +1 more source

Ion Chemistry of VX Surrogates and Ion Energetics Properties of VX: New Suggestions for VX Chemical Ionization Mass Spectrometry Detection

open access: yes, 2016
Room temperature rate constants and product ion branching ratios have been measured for the reactions of numerous positive and negative ions with VX chemical warfare agent surrogates representing the amine (triethylamine) and organophosphonate (diethyl ...
Satoshi Maeda (1247163)   +5 more
core   +1 more source

Vapor Pressure of VX [PDF]

open access: yes, 1999
Abstract : O-ethyl-S-(diisopropylaminoethly) methyl phosphonothiolate (VX) vapor pressure has been measured using a modified ASTM method in which a carrier gas was slowly passed over the liquid phase, and the saturated effluent was analyzed. Data measured in the current work has extended the low end of the range of measured VX vapor pressures from 30 ...
David E. Tevault   +3 more
openaire   +1 more source

Impedance‐Matched High‐Overtone Thickness‐Shear Bulk Acoustic Resonators With Scalable Mode Volume

open access: yesAdvanced Science, EarlyView.
A bottom‐electrode‐free high‐overtone bulk acoustic resonator is achieved by lateral excitation of antisymmetric thickness‐shear modes on a lithium‐niobate‐on‐silicon platform. Planar electrode geometry eliminates conventional loading along the resonance path and confines acoustic energy within the electrode gap.
Zi‐Dong Zhang   +7 more
wiley   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

open access: yesAdvanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang   +10 more
wiley   +1 more source

Large Temperature‐invariant Anomalous Nernst Effect in Non‐collinear Antiferromagnet Mn3Pt

open access: yesAdvanced Science, EarlyView.
Based on the noncollinear antiferromagnetic Mn3Pt thin films, the composition‐tunable Mn‐3d orbital states directly govern the Berry curvature. As a result, a giant and temperature‐invariant anomalous Nernst coefficient of 0.71 µV/K is achieved under Mn‐rich conditions.
Pengwei Gong   +16 more
wiley   +1 more source

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