Results 111 to 120 of about 1,291 (151)

Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage. [PDF]

Nat Cell Biol
Szmyd R, Casolin S, French L, Manjón AG, Walter M, Cavalli L, Nelson CB, Page SG, Dhawan A, Hau E, Pickett HA, Gee HE, Cesare AJ.   +12 more
europepmc   +1 more source

In through the out door: A loop-binding-first model for topological cohesin loading. [PDF]

Bioessays
Rhind N.
europepmc   +1 more source

Highly Sensitive Labeling, Clickable Functionalization, and Glycoengineering of the MUC1 Neighboring System. [PDF]

JACS Au
Wang G, Chen Y, Wei Y, Zheng L, Jiao J, Guo Y.   +5 more
europepmc   +1 more source

Lactylation in cancer: Unveiling new layers of complexity. [PDF]

Innovation (Camb)
Zhang S, Xie B, Zhu X, Dong S, Li M.
europepmc   +1 more source

Loop Extrusion Machinery Impairments in Models and Disease. [PDF]

Cells
Ryzhkova A, Maltseva E, Battulin N, Kabirova E.   +3 more
europepmc   +1 more source

Linear RAG scanning mediates editing of Igκ variable region repertoires. [PDF]

Nature
Li X, Hu H, Zhang Y, Zhu T, Guan Y, Xu K, Lin X, Hebert C, Batra H, Zhou J, Ba Z, Wesemann DR, Ye AY, Alt FW.   +13 more
europepmc   +1 more source

Cell enlargement causes mitotic errors and aneuploidy in cells that evade senescence after CDK4/6 inhibition

Pareri AU, Losito M, Foijer F, Saurin AT.   +3 more
europepmc   +1 more source

The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension [PDF]

Cell, 2017
The spatial organization of chromosomes influences many nuclear processes including gene expression. The cohesin complex shapes the 3D genome by looping together CTCF sites along chromosomes. We show here that chromatin loop size can be increased and that the duration with which cohesin embraces DNA determines the degree to which loops are enlarged ...
Bas Van Steensel, Benjamin Rowland, Mario Amendola   +2 more
exaly   +7 more sources

Wapl Controls the Dynamic Association of Cohesin with Chromatin [PDF]

Cell, 2006
Cohesin establishes sister-chromatid cohesion from S phase until mitosis or meiosis. To allow chromosome segregation, cohesion has to be dissolved. In vertebrate cells, this process is mediated in part by the protease separase, which destroys a small amount of cohesin, but most cohesin is removed from chromosomes without proteolysis.
Alexander Schleiffer, Karl Mechtler, Jan-Michaél Peters   +2 more
exaly   +3 more sources

Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl [PDF]

Nature, 2017
Mammalian genomes are spatially organized by CCCTC-binding factor (CTCF) and cohesin into chromatin loops and topologically associated domains, which have important roles in gene regulation and recombination. By binding to specific sequences, CTCF defines contact points for cohesin-mediated long-range chromosomal cis-interactions.
Antonio Tedeschi, Georg Busslinger, Roman R Stocsits   +2 more
exaly   +4 more sources