Results 101 to 110 of about 1,661 (174)
Clinical, in vitro, and in vivo evidence of WAPL as a novel cohesinopathy gene and phenotypic driver of 10q22.3q23.2 genomic disorder
Cohesin is a fundamental genome-organizing complex that orchestrates three-dimensional chromosome folding and gene expression via DNA loop extrusion. Alterations to genes encoding cohesin subunits and cohesin loaders cause Mendelian disorders, including ...Rosenberg-Fogler, Hallel, Faour, Kamli N. W., Maitz, Silvia, Le Caignec, Cedric, Boone, Philip M., von Wintzingerode, Lydia, Gusella, James, Munasinghe, Jeeva, Sinnema, Margje, T\uf8rring, Pernille M., Crunk, Amy, Houlier, Marine, Fulton, Anne, Hallstrom, Grey, Chiriatti, Luigi, McKay, Victoria, Higgs, Jenny, Shillington, Amelle, Salani, Monica, Zampino, Giuseppe, Delahaye-Duriez, Andree, Devriendt, Koenraad, Nakamori, Sachiko, Krepischi, Ana C.V., Monteil, Danielle, Wojcik, Monica H., Kerkhof, Jennifer, Ballal, Sonia, Harripaul, Ricardo, Baxter, Megan F., Rzasa, Jessica, Andersen, Erica F., Mohajeri, Kiana, Radio, Francesca Clementina, Taylor, Jenny C., Auwerx, Chiara, Vitobello, Antonio, Collins, Ryan, Safraou, Hana, Ladda, Roger, Maier, Olivier, Jamra, Rami Abou, Bhavsar, Riya, Srivastava, Siddharth, Robert, Leema, Kenna, Margaret, Carvalho, Laura M.L., Kaiser, Frank J., Westphal, Dominik S., Oliveira, Mariana Moys\ue9s, Tsoulaki, Olga, Siebold, Dorothea, Buchanan, Catherine, McCune, Madison J., Lemanski, John, Moldovan, Oana, Umair, Muhammad, Lewis, Zoe K., Sherr, Elliott, Larson, Matthew, Delanne, Julian, Grafstein, Julia, de Esch, Celine E.F., Beauchamp, Roberta L, Wilson, William, Watt, Amy, Agrawal, Pankaj, Bruel, Ange-Line, Kleefstra, Tjitske, Orec, Laura, Eliot Shearer, A., Riedhammer, Korbinian M., Pfundt, Rolph, Vincent, Marie, Smith, Laura, Denhoff, Erica, Schliesske, Sophia, Seaby, Eleanor G., Duncan, Laura, Neuser, Sonja, Springer, Danielle, Male, Alison, Wayhelova, Marketa, Stegmann, Alexander P.A., Tai, Derek J. C., Domingo, Aloysius, Stevens, Servi, Peterlin, Borut, Nuttle, Xander, Macek, Milan, Erdin, Serkan, Wright, Zsabre, Currall, Benjamin, Tartaglia, Marco, Sell, Susan, Vanhoutte, Els, Nizon, Mathilde, Argilli, Emanuela, Immken, LaDonna, Kimmig, Lara Kristina, Harel, Tamar, Iascone, Maria, Pouncey, Jill, Famularo, Laura, Joyce, Eric, Lima, Gloria, O\u2019Keefe, Kathryn, Yadav, Rachita, Rosenfeld, Jill A., Lanoue, Louise, Havlovicova, Marketa, Levy, Michael A, Bortola, Debora R., Araiza, Renee, Jana, Bimal, Kao, Emeline, Lucente, Diane, Stevens, Cathy, Agrawal, Neena, Bertsche, Astrid, Haghshenas, Sadegheh, Parenti, Ilaria, Braun, Dominique, Cogne, Benjamin, Thompson, Michelle L., Mau Them, Frederic Tran, Holmes, Lauren, Isidor, Bertrand, Khan, Amjad, Pfeifer, Karl E., Burt, Nicholas D., Yuan, Bo, Bothe, Viktoria, Brasch-Andersen, Charlotte, Wentzensen, Ingrid M., Fu, Jack, Denomm\ue9-Pichon, Anne-Sophie, Sadikovic, Bekim, Rodan, Lance, McConkey, Haley, Talkowski, Michael E., Mohamed, Abucar, Malikova, Marcela, Bergant, Gaber, Faivre, Laurence, Krey, Ilona, Lynch, Sally Ann, Kraus, Eva-Maria, Genetti, Casie, Karbone, Kaycee, Surette, Eric +150 morecore +1 more sourceCTCF, WAPL and PDS5 proteins control the formation of TADs and loops by cohesin
, 2017 Mammalian genomes are organized into compartments, topologically-associating domains (TADs) and loops to facilitate gene regulation and other chromosomal functions. Compartments are formed by nucleosomal interactions, but how TADs and loops are generated Roman Stocsits, Gordana Wutz, Peter Fraser, Matthias Muhar, Nike Walther, M Julius Hossain, Birgit Koch, Jan-Michael Peters, Kota Nagasaka, Jan Ellenberg, Csilla Várnai, Stefan Schoenfelder, Moritz Kueblbeck, David A Cisneros, Wen Tang, Gregor Jessberger, Johannes Zuber +16 morecore +1 more sourceTopologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins
, 2017 Mammalian genomes are spatially organized into compartments, topologically associating domains (TADs), and loops to facilitate gene regulation and other chromosomal functions. How compartments, TADs, and loops are generated is unknown.Gordana Wutz, Peter Fraser, Nike Walther, Peters, Jan-Michael, Ellenberg, Jan, Muhar, Matthias, M Julius Hossain, Walther, Nike, Roman R Stocsits, Birgit Koch, Várnai, Csilla, Schoenfelder, Stefan, Fraser, Peter, Hossain, M Julius, Csilla Várnai, Várnai, Csilla; id_orcid, Wutz, Gordana, Stefan Schoenfelder, Stocsits, Roman R, David A Cisneros, Wen Tang, Gregor Jessberger, Kueblbeck, Moritz, Jan‐Michael Peters, Koch, Birgit, Zuber, Johannes, Matthias Muhar, Nagasaka, Kota, Peters, Jan‐Michael, Cisneros, David A, Jessberger, Gregor, Tang, Wen, Kota Nagasaka, Jan Ellenberg, Cisneros, David A.,, Moritz Kueblbeck, Johannes Zuber +36 morecore +1 more sourceGenome folding and nuclear speckles converge to orchestrate fibroblast activation. [PDF]
Sci AdvGardner Z, Linares-Saldana R, Haridhasapavalan KK, Méndez Fernández PO, Barka V, Yang R, Koch-Bojalad B, Padmanabhan A, Wang Q, Shah PP, Nguyen SC, Joyce EF, Jain R. +12 moreeuropepmc +1 more source
