Results 141 to 150 of about 108,453 (351)

PKM2 promotes reductive glutamine metabolism

Cancer Biology & Medicine, 2018
Objective: Pyruvate kinases M (PKM), including the PKM1 and PKM2 isoforms, are critical factors in glucose metabolism. PKM2 promotes aerobic glycolysis, a phenomenon known as “the Warburg effect”.
Miao Liu, Yuanyuan Wang, Yuxia Ruan, Changsen Bai, Li Qiu, Yanfen Cui, Guoguang Ying, Binghui Li   +7 more
doaj   +1 more source

Energy Boost: The Warburg Effect Returns in a New Theory of Cancer [PDF]

, 2004
K. Garber
openalex   +1 more source

‘Reverse Warburg effect’ of cancer‑associated fibroblasts (Review)

, 2022
Lin Liang, Wentao Li, Xin Li, Xi Jin, Qianjin Liao, Yanling Li, Yanhong Zhou   +6 more
openalex   +2 more sources

Determination of the Exchange Current Density at Lithium │ Polymer Electrolyte Interfaces

Advanced Science, EarlyView.
This work presents a comprehensively validated method to determine the exchange current density (j0) at the interface of lithium metal and polymer electrolytes by combining electrochemical impedance spectroscopy with Bayesian inference and distribution of relaxation times analyses to successfully deconvolute solid electrolyte interphase and charge ...
Katrin Geng, Bryce A. Tappan, Stefano Passerini, Yang Shao‐Horn, Dominic Bresser   +4 more
wiley   +1 more source

The role of cellular oxidative stress in regulating glycolysis energy metabolism in hepatoma cells

Molecular Cancer, 2009
Background The Warburg effect has been found in a wide spectrum of human cancers, however the underlying mechanisms are still unclear. This study aims to explore the role of cellular oxidative stress in relation to glycolysis and the Warburg effect in ...
Shi Dong-yun, Xie Fei-zhou, Zhai Chao, Stern Jeremy S, Liu Yang, Liu Shan-lin   +5 more
doaj   +1 more source

LINC01224 promotes the Warburg effect in gastric cancer by activating the PI3K/AKT/mTOR/HIF-1α axis [PDF]

, 2023
Yuling Bin, Minji Liu, Rong He, Pingfei Tang, Weiming Qu, Dajun Wu, Lin Tan, Qiongjia Ai, Qian Wang, Peng Jiang, Defeng Li, Hongsai Hu   +11 more
openalex   +1 more source

Targeting the CMKLR1‐Mediated Signaling Rebalances Immunometabolism State in Middle‐Age Testicular Macrophages

Advanced Science, EarlyView.
In middle age, testicular CMKLR1⁺ macrophages exhibited a pro‐inflammatory immunometabolic profile, mediated by adipose signals associated with high BMI. However, inhibition of CMKLR1 signaling, either through Cmklr1 genetic ablation or treatment with a CMKLR1 antagonist peptide, can reverse this phenotype.
Zhendong Zhu, Feifei Du, Yang Liu, Jinchunzi Yang, Lei Ge, Tianxia Xiao, Mengxia Li, Jie Chen, Jia Tang, Yali Yang, Jian V. Zhang   +10 more
wiley   +1 more source

Warburg Effect and Its Role in Tumor Cell Metabolism

, 2022
Aastha Sharma, J Luo, N Solimini, S Elledge, R Gatenby, K Smallbone, P Maini, O Warburg, F Wind, E Negelein, M Vander Heiden, L Cantley, C Thompson, O Warburg, R Cairns, I Papandreou, N Denko, R Gatenby, R Gillies, J Chen, J Lucas, T Schroeder, S Mori, J Wu, J Nevins, M Dewhirst, M West, J Chi, J Xie, H Wu, C Dai, Q Pan, Z Ding, D Hu, B Ji, Y Luo, X Hu, C Dang, S North, M Moenner, A Bikfalvi, D Hanahan, J Folkman, G Semenza, G Wang, C Schofield, P Ratcliffe, R Wenger, J Gordan, C Thompson, M Simon, K Kondo, J Klco, E Nakamura, M Lechpammer, W Kaelin, Jr, G Wang, B Jiang, E Rue, G Semenza, M Ivan, K Kondo, H Yang, W Kim, J Valiando, M Ohh, A Salic, J Asara, W Lane, W Kaelin, Jr, Z Bhujwalla, D Artemov, P Ballesteros, S Cerdan, R Gillies, M Solaiyappan, P Vaupel, E Boedtkjer, J Moreira, M Mele, P Vahl, V Wielenga, P Christiansen, V Jensen, S Pedersen, C Aalkjaer, H Izumi, M Takahashi, H Uramoto, Y Nakayama, T Oyama, K Wang, Y Sasaguri, S Nishizawa, K Kohno, C Justus, L Dong, L Yang   +99 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Cathode Electrolyte Interphase Engineering by Quaternized Chitosan for Stabilized Li–SPAN Batteries

Advanced Science, EarlyView.
In this work, quaternized chitosan (QCS) is reported as an additive optimizing the sulfurized polyacrylonitrile (SPAN) cathode/electrolyte interphase (CEI). Its high positive charge density adsorbs PF6− anions, enriching the Helmholtz layer with aggregates. This promotes rapid anion desolvation, forming an anion‐derived CEI enriched in LiF.
Runhe He, Hao Liu, Qing Gao, Dong Cai, Kuikui Xiao, Yinhang Zhang, Xinmin Zhang, Xianyang Cheng, Yuhui Wang, Lixing Kang, Huagui Nie, Yatao Liu, Zhi Yang   +12 more
wiley   +1 more source